Vaccinex Announces Exercise of Warrants for $6.2 Million in Gross Proceeds

Rhea-AI Summary

Vaccinex (Nasdaq: VCNX), a clinical-stage biotech company focusing on neurodegenerative disease treatment, has announced the exercise of outstanding warrants resulting in $6.2 million in gross proceeds. The transaction involves:

1. Immediate exercise of warrants to purchase 1,067,492 shares at $5.636 per share
2. Issuance of 827,483 shares and pre-funding of 240,009 shares
3. New warrants issued for up to 1,601,238 additional shares at $5.636 per share, expiring in 5 years

Notably, entities affiliated with the CEO and Board Chairman accounted for 51% of the securities in the transaction. The closing is expected on September 18, 2024, subject to customary conditions.

Positive

• Raised $6.2 million in gross proceeds through warrant exercise
• New warrants issued at-the-market price, potentially providing future funding
• 51% of securities in the transaction from insiders, showing management confidence

Negative

• Dilution of existing shareholders due to issuance of new shares
• Potential future dilution from new warrants if exercised

Financial Analyst

The $6.2 million in gross proceeds from warrant exercises provides a short-term cash infusion for Vaccinex, bolstering its financial position. However, this comes at the cost of potential dilution for existing shareholders. The reduced exercise price of $5.636 per share, compared to the previous closing price, suggests a discount to incentivize exercise. The involvement of insiders, including the CEO and Chairman, in 51% of the transaction demonstrates insider confidence but also raises questions about the company's ability to attract outside investment. The issuance of new warrants at the same price indicates a continued need for future funding, which may pressure the stock price in the long term.

Biotechnology Expert

Vaccinex's focus on SEMA4D inhibition for neurodegenerative diseases represents an innovative approach in a challenging therapeutic area. The company's ability to secure additional funding through this warrant exercise is crucial for advancing its clinical programs. However, the reliance on warrants and insider participation suggests external investor interest, which could be indicative of skepticism about the company's technology or market potential. The lack of specific clinical milestones or progress updates in this financial announcement leaves questions about the current state of Vaccinex's pipeline and the immediate use of these funds.

Market Research Analyst

The market's reaction to this financing will be telling. While the immediate cash injection is positive, the dilutive effect and the need for ongoing funding could dampen investor enthusiasm. The at-market pricing of the new warrants suggests a neutral outlook on near-term stock performance. The high insider participation rate of 51% could be viewed positively as a sign of confidence, but it also highlights a lack of broader market interest. Vaccinex's ability to translate this funding into tangible clinical progress will be critical for future market perception and potential partnerships in the competitive neurodegenerative disease space.

ROCHESTER, N.Y., Sept. 18, 2024 (GLOBE NEWSWIRE) -- Vaccinex, Inc. (Nasdaq: VCNX) (“Vaccinex” or the “Company”), a clinical-stage biotechnology company pioneering a differentiated approach to treating neurodegenerative disease by blocking astrogliosis and neuroinflammation through the inhibition of SEMA4D, announced today the entry into definitive agreements for the immediate exercise of outstanding warrants to purchase an aggregate of 1,067,492 shares of common stock (the “Existing Warrants”) at the reduced exercise price of $5.636 per share, resulting in the issuance of 827,483 shares and the pre-funding of 240,009 shares.

In consideration for the immediate exercise of the warrants for cash and the payment of an additional $0.125 per new warrant, the exercising holders will also receive new warrants to purchase shares of common stock in a private placement pursuant to Section 4(a)(2) of the Securities Act of 1933, as amended (the “Securities Act”). The new warrants will be exercisable into an aggregate of up to 1,601,238 shares of common stock, at an exercise price of $5.636 per share (priced at-the-market under the rules of the Nasdaq Stock Market) and will expire five years after issuance.

The gross proceeds to the Company from the exercise of the Existing Warrants together with the sale of the new warrants is expected to be approximately $6.2 million. The closing of the transaction is expected to occur on or about September 18, 2024, subject to satisfaction of customary closing conditions.

Participants in the transaction include entities affiliated with by Maurice Zauderer, President and CEO of the Company, and Albert D. Friedberg, Chairman of the Company’s board of directors. These entities accounted for approximately 51% of the securities in the transaction.

Roth Capital Partners is acting as the Company’s financial advisor for this transaction.

An aggregate of 768,268 of the shares of common stock issuable upon exercise of the Existing Warrants are registered for sale or resale pursuant to effective registration statements. The warrants offered in the private placement have not been registered under the Securities Act or applicable state securities laws. The Company has agreed to file a resale registration statement with the SEC to register the resale of the shares of common stock issuable upon exercise of the new warrants.

This press release shall not constitute an offer to sell or the solicitation of an offer to buy these securities, nor shall there be any sale of these securities in any state or other jurisdiction in which such offer, solicitation or sale would be unlawful prior to the registration or qualification under the securities laws of any such state or other jurisdiction.

About Vaccinex, Inc.

Vaccinex, Inc. is pioneering a differentiated approach to treating slowly progressive neurodegenerative diseases and cancer through the inhibition of semaphorin 4D (SEMA4D). The Company’s lead drug candidate, pepinemab, blocks SEMA4D, a potent biological effector that it believes triggers damaging inflammation in chronic diseases of the brain and prevents infiltration and activation of immune cells in tumors. Pepinemab was studied as a monotherapy in the Phase 1b/2 SIGNAL-AD study in Alzheimer’s Disease, and the Company has previously published promising Phase 2 data in Huntington’s disease. Vaccinex believes pepinemab could also be an important contributor to combination therapy in AD. In oncology, pepinemab is being evaluated in combination with KEYTRUDA^® in the Phase 1b/2 KEYNOTE-B84 study in recurrent or metastatic head and neck cancer (HNSCC) and in combination with BAVENCIO^® in a Phase 1b/2 study in patients with metastatic pancreatic adenocarcinoma (PDAC). The oncology clinical program also includes several investigator-sponsored studies in solid tumors including breast cancer and melanoma.

Vaccinex has global commercial and development rights to pepinemab and is the sponsor of the KEYNOTE-B84 study which is being performed in collaboration with Merck Sharp & Dohme Corp, a subsidiary of Merck and Co, Inc. Kenilworth, NJ, USA.

KEYTRUDA is a registered trademark of Merck Sharp & Dohme Corp., a subsidiary of Merck & Co. Inc., Kenilworth, NJ, USA. BAVENCIO^®/avelumab is provided by Merck KGaA, Darmstadt, Germany, previously as part of an alliance between the healthcare business of Merck KGaA, Darmstadt, Germany and Pfizer.

About Pepinemab

Pepinemab is a humanized IgG4 monoclonal antibody designed to block SEMA4D, which can bind to plexin-B1 receptors to trigger collapse of the actin cytoskeleton in cells and lead to loss of homeostatic functions of astrocytes and other glial cells in the brain and of dendritic cells in immune tissue. Pepinemab appears to have been well-tolerated with a favorable safety profile in multiple clinical trials in different neurological and cancer indications.

Forward Looking Statements

To the extent that statements contained in this press release are not descriptions of historical facts regarding Vaccinex, Inc. (“Vaccinex,” “we,” “us,” or “our”), they may be forward-looking statements reflecting management’s current beliefs and expectations. Such statements include, but are not limited to, statements about our plans, expectations and objectives with respect to our clinical trials of pepinemab in various indications and the use and potential benefits of pepinemab treatment in AD and HD, the potential and prospects for continuing late stage development of pepinemab, including as part of a prospective partnership, Vaccinex’s ability to finance its current development plans with pre-existing cash balance and funds from the transaction, and other statements identified by words such as “may,” “will,” “appears,” “expect,” “planned,” “anticipate,” “estimate,” “intend,” “hypothesis,” “potential,” “suggest”, “advance,” “subject to” and similar expressions or their negatives (as well as other words and expressions referencing future events, conditions, or circumstances). Forward-looking statements involve substantial risks and uncertainties that could cause the outcome of our research and pre-clinical and clinical development programs, future results, performance, or achievements to differ significantly from those expressed or implied by the forward-looking statements. Such risks and uncertainties include, among others, our ability to continue as a going concern, the possible delisting of our common stock from Nasdaq if the Company is unable to regain and sustain compliance with the Nasdaq listing standards, the risk the transaction does not close, the impact of inflation on our expenses and business, uncertainties inherent in the execution, cost, enrollment and completion of clinical trials, uncertainties related to regulatory approval, risks related to our dependence on our lead product candidate pepinemab, and other matters that could affect our development plans or the commercial potential of our product candidates. Except as required by law, we assume no obligation to update these forward-looking statements. For a further discussion of these and other factors that could cause future results to differ materially from any forward-looking statement, see the section titled “Risk Factors” in our periodic reports filed with the Securities and Exchange Commission (the “SEC”) and the other risks and uncertainties described in Vaccinex’s most recent year-end Annual Report on Form 10-K and subsequent SEC filings.

Investor Contact
Elizabeth Evans, PhD
Chief Operating Officer, Vaccinex, Inc.
(585) 271-2700
eevans@vaccinex.com

FAQ

How much did Vaccinex (VCNX) raise through the warrant exercise?

Vaccinex (VCNX) raised approximately $6.2 million in gross proceeds through the exercise of outstanding warrants and the sale of new warrants.

What was the exercise price for the Vaccinex (VCNX) warrants?

The exercise price for the Vaccinex (VCNX) warrants was reduced to $5.636 per share.

How many new warrants did Vaccinex (VCNX) issue in the transaction?

Vaccinex (VCNX) issued new warrants exercisable for up to 1,601,238 shares of common stock at $5.636 per share, expiring five years after issuance.

When is the expected closing date for Vaccinex's (VCNX) warrant exercise transaction?

The expected closing date for Vaccinex's (VCNX) warrant exercise transaction is on or about September 18, 2024, subject to customary closing conditions.