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TradeUP Acquisition Corp. (NASDAQ: UPTD) is a publicly traded special purpose acquisition company (SPAC) incorporated on January 6, 2021, under the laws of the State of Delaware. The company was established with the primary objective of merging with or acquiring one or more businesses. On September 30, 2022, TradeUP entered into a definitive business combination agreement with Estrella Biopharma, Inc., a preclinical-stage biopharmaceutical company specializing in cancer therapeutics.
TradeUP recently announced the successful closing of this business combination, resulting in the formation of Estrella Immunopharma, Inc. The new entity, led by Estrella Founder and CEO Dr. Cheng Liu, focuses on developing T-cell therapies to address treatment challenges for patients with blood cancers and solid tumors. Estrella's lead product candidates, EB103 and EB104, utilize Eureka's ARTEMIS® technology targeting CD19 and CD22 proteins, which are expressed on the surface of B-cell leukemias and lymphomas.
Estrella has also formed a collaboration with Imugene Limited to research the combined use of EB103 with Imugene's oncolytic virus CF33-CD19t, employing a 'mark and kill' strategy for treating solid tumors. The business combination and additional financings have provided the newly formed Estrella Immunopharma, Inc. with approximately $23.11 million in available cash, positioning the company to advance its clinical programs and deliver long-term value to its stockholders.
Before the successful merger, TradeUP had announced interim and special meetings to vote on the proposed business combination and an extension proposal to delay the deadline for completing a business combination from July 19, 2023, to July 14, 2024. This extension was critical to ensure the seamless transition and successful merger with Estrella Biopharma, Inc., which is now trading on NASDAQ under the ticker symbols 'ESLA' and 'ESLAW' effective October 2, 2023.
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