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Twist Bioscience Corporation, symbol TWST, stands at the forefront of synthetic biology with an innovative approach to DNA synthesis. The company's core expertise lies in developing a proprietary semiconductor-based synthetic DNA manufacturing process. This process utilizes a unique 10,000-well silicon platform, markedly different from the traditional 96-well plastic plates. This advanced platform enables the production of synthetic biology tools, such as oligonucleotides, genes, pathways, chassis, and genomes, in a more efficient, cost-effective, and high-throughput manner.
The implications of Twist Bioscience's technology are profound, offering the potential to revolutionize various fields. By synthesizing DNA on silicon, the company overcomes existing production inefficiencies, ensuring rapid and high-quality DNA synthesis. This capability is crucial for accelerating developments in personalized medicine, sustainable chemical production, agricultural improvements, in vivo diagnostics, biodetection, and even data storage.
Based primarily in the United States, Twist Bioscience derives the majority of its revenue from its home market. The company's strategic partnerships and ongoing projects reflect its commitment to pioneering advancements in synthetic biology. Having positioned itself as a leader in the field, Twist Bioscience continues to support researchers and industries by providing high-quality synthetic DNA rapidly, enabling them to seize emerging opportunities.
For more information, please visit Twist Bioscience.
Twist Bioscience (NASDAQ: TWST) announced it will release its fiscal 2024 third quarter financial results on Friday, August 2, 2024, before market opening. The company will host a conference call and live audio webcast at 8:00 a.m. ET to discuss the results and provide business updates. The press release with financial results will be accessible on Twist Bioscience's website under the Investor Relations section. Interested participants can register on the company's website to receive the necessary dial-in information for the call. A webcast replay will be available for two weeks.
Twist Bioscience (NASDAQ: TWST) has expanded its high-throughput antibody portfolio with the launch of the CHO Express Antibodies, complementing their existing HEK293 antibodies. This expansion aims to support biopharma companies by providing customizable, cost-effective, and scalable antibody production solutions. CHO cell lines are pivotal in biotherapeutic drug manufacturing, and Twist's new service can deliver sequence-perfect IgG antibodies in as few as 13 business days. The antibodies range from 15 μg to 3,000 μg and include detailed yield data for screening. This development improves the efficiency and reduces the costs associated with antibody discovery and production.
Twist Bioscience (NASDAQ: TWST) has introduced a synthetic RNA control for H5N1 Influenza A, a key contributor to Highly Pathogenic Avian Influenza (HPAI). The new control covers 99.9% of the hemagglutinin (HA) and neuraminidase (NA) genome regions, facilitating enhanced research without the need for live viruses.
CEO Emily M. Leproust highlighted the importance of providing innovative tools for global monitoring and vaccine development. The synthetic control allows work to be undertaken in BSL-1 labs, speeding up research while maintaining high biosecurity standards.
This launch is part of Twist's broader portfolio of synthetic viral controls and research tools, aimed at supporting next-generation sequencing (NGS) and polymerase chain reaction (PCR) assays. The company also offers products for other viral and respiratory diseases, including a comprehensive viral research panel for detecting H5N1 in wastewater.
Twist Bioscience (NASDAQ: TWST) has announced the discovery of TB206-001, a first-in-class antibody targeting the adenosine A2A receptor (A2AR), which could enhance cancer immunotherapy. The preclinical study, published in PLOS ONE, shows that TB206-001 has high affinity and tumor-suppressing activity, especially in colon tumor-bearing HuCD34-NCG mice, outperforming PD-1 inhibitors. The antibody targets GPCRs, common in immune cells and certain cancers, and works by blocking A2AR, thereby activating immune cells. Twist Bioscience is offering TB206-001 for out-licensing, indicating its potential for further clinical development.
Twist Bioscience (NASDAQ: TWST) announced its participation in the U.S. AI Safety Institute Consortium (AISIC), a group formed by the Department of Commerce’s National Institute of Standards and Technology (NIST). As part of the consortium, Twist Bioscience aims to advance the development and deployment of safe and trustworthy AI. The company emphasizes its commitment to biosecurity, leveraging its high-quality synthetic DNA and silicon platform to support the creation of interoperable safety standards. The consortium comprises over 200 member companies, including industry leaders, academia, government entities, and civil society organizations, all dedicated to ensuring the responsible growth of AI technologies.
Twist Bioscience (NASDAQ: TWST), a biotechnology company specializing in synthetic DNA, has announced its executives' participation in several upcoming investor conferences. Patrick Finn, Ph.D., president and COO, will join a fireside chat at the Leerink Partners Healthcare Crossroads Conference on May 29 in Austin, TX. Emily Leproust, Ph.D., CEO and co-founder, will present at the William Blair Growth Stock Conference on June 4 in Chicago, IL, at the Jefferies Global Healthcare Conference on June 6 in New York, NY, and will participate in a fireside chat at the Goldman Sachs 45th Annual Global Healthcare Conference on June 11 in Miami, FL. The sessions will be webcast live and available on the company's website, with replays accessible for 30 days after the events.
Twist Bioscience (TWST) has launched Twist Multiplexed Gene Fragments (MGFs), pools of directly synthesized double-stranded DNA up to 500 base pairs in length, with no limit on sequence number, enabling high-throughput screening applications. This offering allows for rapid screening of diverse targets for CRISPR and genome engineering, antibody discovery, protein engineering, and more. The customizable fragments have a quick turnaround time, starting at 8 business days, making them versatile for various applications.
Twist Bioscience announced the granting of 87,200 restricted stock units to 26 new employees as inducement for joining the company. The RSUs vest over a 48-month period for each employee, with 25% vesting on the one year anniversary of employment and 1/16 vesting quarterly thereafter.
Twist Bioscience (NASDAQ: TWST) reported a record revenue of $75.3M in the second quarter of fiscal 2024, showing a 25% increase over the same period in fiscal 2023. Orders also grew by 45% to $93.2M. The company increased its revenue guidance for fiscal 2024 to a range of $300M to $304M and its gross margin guidance to 41.5% to 42.0%. Twist Bioscience continues to focus on profitability and aims to improve gross margin to over 50% by the end of fiscal 2025.
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