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Twist Bioscience Corporation, symbol TWST, stands at the forefront of synthetic biology with an innovative approach to DNA synthesis. The company's core expertise lies in developing a proprietary semiconductor-based synthetic DNA manufacturing process. This process utilizes a unique 10,000-well silicon platform, markedly different from the traditional 96-well plastic plates. This advanced platform enables the production of synthetic biology tools, such as oligonucleotides, genes, pathways, chassis, and genomes, in a more efficient, cost-effective, and high-throughput manner.
The implications of Twist Bioscience's technology are profound, offering the potential to revolutionize various fields. By synthesizing DNA on silicon, the company overcomes existing production inefficiencies, ensuring rapid and high-quality DNA synthesis. This capability is crucial for accelerating developments in personalized medicine, sustainable chemical production, agricultural improvements, in vivo diagnostics, biodetection, and even data storage.
Based primarily in the United States, Twist Bioscience derives the majority of its revenue from its home market. The company's strategic partnerships and ongoing projects reflect its commitment to pioneering advancements in synthetic biology. Having positioned itself as a leader in the field, Twist Bioscience continues to support researchers and industries by providing high-quality synthetic DNA rapidly, enabling them to seize emerging opportunities.
For more information, please visit Twist Bioscience.
Twist Bioscience has launched Exome 2.0, boasting the most comprehensive coverage of protein-coding and noncoding regions of the genome. This innovative product enhances sequencing efficiency with lower costs and best-in-class performance, offering improved uniformity and a higher on-target rate. The Exome 2.0 is designed for applications addressing rare diseases and inherited disorders. The release underscores the company's commitment to supporting genomics researchers with customizable and efficient solutions.
Twist Bioscience has announced a collaboration with the Broad Institute to distribute the Twist Alliance Clinical Research Exome, a next-generation sequencing panel targeting genes related to cancer and inherited diseases. Designed using validated clinical data, this panel enhances sequencing efficiency and supports the Broad's efforts in processing over 250,000 samples. It will be available mid-October, combining various genomic regions to facilitate deeper insights into genetic variants for therapeutic applications.
Twist Bioscience Corporation (NASDAQ: TWST) has appointed Steffen Hellmold as senior vice president of business development for data storage. This newly created position aims to bolster the company's commercialization efforts in DNA data storage solutions, which are anticipated to be significant in the market. Hellmold, previously of Western Digital, brings extensive experience in storage innovation. CEO Emily M. Leproust emphasized that his appointment will help establish critical relationships and define the commercialization strategy as they advance in this innovative field.
Twist Bioscience Corporation (TWST) and Centogene N.V. (CNTG) have partnered to develop custom assay kits targeting the diagnosis of rare diseases. This collaboration aims to enhance genetic testing accessibility for patients, ultimately improving understanding and treatment of rare conditions. Although no financial details were disclosed, the partnership seeks to utilize Centogene's extensive Bio/Databank and Twist's DNA synthesis technologies. The initiative is part of Centogene's goal to drive insights and potentially cure up to 100 rare diseases within the next decade.
Twist Bioscience Corporation (NASDAQ: TWST) has expanded its product offerings with the launch of the Twist Alliance Pan-Cancer Methylation Panel, designed for extensive cancer research applications. This panel, developed in collaboration with the Regeneron Genetics Center, covers 31 cancer types, optimizing sequencing costs and analysis complexity. Validation of the panel shows its effectiveness in differentiating cancer from non-malignant tissues. Twist's Alliance Panels aim to enhance research capabilities by providing expert-designed, clinically validated tools.
Twist Bioscience Corporation (NASDAQ: TWST) has appointed Dennis Cho as senior vice president, general counsel, and chief ethics and compliance officer. With over 25 years of corporate legal experience in the biotech industry, Cho aims to support Twist’s growth across synthetic biology and genomics. Previously, he held significant roles at CytomX Therapeutics and Seattle Genetics. CEO Emily Leproust expressed confidence in Cho's expertise to guide the company’s strategic initiatives. Twist strives to revolutionize DNA synthesis and applications across various industries, including healthcare and agriculture.
Twist Bioscience Corporation (TWST) announced promising results for its antibody candidate TB202-3, showing potent binding to various SARS-CoV-2 variants, including the E484K, N501Y, and D614G mutations. Conducted by the Coronavirus Immunotherapy Consortium, the analysis demonstrated that TB202-3 completely obstructs the virus's binding to human ACE2, indicating its potential effectiveness against COVID-19. The company is also advancing a new antibody, TB339-031, targeting additional variants. These findings underscore the antibody's broad applicability amidst evolving viral strains.
Twist Bioscience Corporation (NASDAQ: TWST) has announced a collaboration with deepCDR, focused on advanced antibody discovery using deep learning algorithms. This partnership aims to enhance Twist's ability to generate large panels of fully human antibody sequences, utilizing new AI Hypermutated scFv libraries. The collaboration is expected to streamline preclinical development by reducing validation work. Twist's innovative silicon platform enables the manufacturing of high-quality synthetic DNA, which is crucial for various applications, including drug discovery and genomics.
Illumina Ventures has closed its second investment fund, raising
Twist Bioscience Corporation announces the availability of synthetic RNA reference controls for the latest SARS-CoV-2 variants, AY.1 and AY.2, enhancing the accuracy of diagnostic tests. The company now offers a total of 22 synthetic RNA controls targeting SARS-CoV-2 and 15 for respiratory viruses. This initiative demonstrates Twist's commitment to monitoring viral evolution and developing effective testing tools. The synthetic controls are used globally in various assays and are noted for their sequence verification and coverage of the full viral genome.
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