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Twist Bioscience Corporation (TWST) is a pioneering company in the field of synthetic biology, specializing in the industrial-scale production of synthetic DNA. At the heart of its operations is a proprietary semiconductor-based DNA synthesis platform, which represents a significant advancement over traditional methods. By synthesizing DNA on a 10,000-well silicon platform instead of conventional 96-well plastic plates, Twist Bioscience achieves unprecedented levels of efficiency, scalability, and cost-effectiveness. This innovation enables the production of high-quality synthetic DNA at a faster pace and lower cost, addressing key inefficiencies in the industry.
The company's product offerings include a wide range of synthetic biology tools such as oligonucleotides, genes, pathways, chassis, and genomes. These tools are critical for applications across multiple industries, including pharmaceutical research, personalized medicine, agriculture, sustainable chemical production, and emerging fields like DNA data storage and in vivo diagnostics. Twist Bioscience's platform not only accelerates research and development but also empowers organizations to innovate in areas such as biodetection and bioengineering.
Operating primarily in the United States, Twist Bioscience serves a diverse customer base that includes biotech firms, pharmaceutical companies, academic institutions, and industrial research organizations. Its business model revolves around direct sales of synthetic DNA products and services, catering to the growing demand for advanced biological engineering solutions. By leveraging its cutting-edge technology, the company has established itself as a critical enabler in the synthetic biology ecosystem.
The broader synthetic biology industry is characterized by rapid innovation and significant growth potential, driven by advancements in genomics, bioinformatics, and sustainable technologies. Twist Bioscience's focus on high-throughput, cost-effective DNA synthesis positions it as a key player in this dynamic market. However, the company faces competition from other DNA synthesis providers, necessitating continuous investment in research and development to maintain its technological edge.
What sets Twist Bioscience apart is its commitment to overcoming traditional limitations in DNA synthesis. By utilizing silicon-based manufacturing, the company not only enhances production efficiency but also expands the possibilities for synthetic biology applications. This unique approach underscores its role as a transformative force in the industry, enabling researchers and organizations to unlock new opportunities in science and technology.
In summary, Twist Bioscience combines technological innovation with a deep understanding of synthetic biology to deliver high-quality DNA synthesis solutions. Its proprietary platform and diverse product offerings make it a vital partner for industries seeking to harness the power of engineered biology. As the demand for synthetic DNA continues to grow, Twist Bioscience remains at the forefront of enabling groundbreaking advancements across multiple sectors.
Twist Bioscience (NASDAQ: TWST) has entered into an antibody discovery agreement with Kriya Therapeutics, focusing on delivering antibodies via adeno-associated viral gene therapy for oncology applications. This partnership aims to leverage Twist's advanced antibody libraries and Kriya's vector engineering platform. The collaboration seeks to enhance the precision of antibody delivery for cancer treatment and potentially expedite the development of novel gene therapies, thereby providing therapeutic benefits where they are most needed.
Twist Bioscience (NASDAQ: TWST) has joined the Digital Preservation Coalition’s Supporter Program, facilitating collaboration between members on digital content preservation. This program emphasizes the importance of long-term digital data storage solutions. CEO Emily M. Leproust expressed enthusiasm for engaging with members to refine their Century Archive DNA data storage solution. The DPC aims to address challenges faced by organizations storing valuable digital assets. This partnership may enhance Twist's position in the emerging DNA data storage market.
SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Twist Bioscience (NASDAQ: TWST) announced that CEO Emily M. Leproust, Ph.D., will present at several upcoming virtual investor conferences. These include the Truist Securities AI Symposium on March 1 at 9:00 a.m. ET and the Cowen 42nd Annual Health Care Conference on March 7, featuring a fireside chat at 2:10 p.m. ET and a Synthetic Biology Enabling Technologies Panel at 10:30 a.m. ET. The Cowen presentations will be webcast live, with replays available for 30 days post-event. Twist specializes in high-quality synthetic DNA products and applications across various industries.
Twist Bioscience Corporation (NASDAQ: TWST) has completed its upsized public offering of 5,227,272 shares at $55.00 each, raising approximately $269.4 million after costs. This move follows the full exercise of the underwriters' option to purchase an additional 681,818 shares. The proceeds will be allocated towards expanding R&D in pharmaceutical biologics, DNA data storage, and Next-Generation Sequencing (NGS) operations, as well as general corporate purposes and strategic investments.
Twist Bioscience Corporation (NASDAQ: TWST) has priced an upsized public offering of 4,545,454 shares at $55.00 each, aiming for gross proceeds of approximately $250 million. The offering is set to close around February 15, 2022, subject to customary conditions. Proceeds will fund R&D investments, including pharmaceutical biologics drug discovery and DNA data storage, as well as scaling operations and supporting global expansion. The underwriters are granted a 30-day option to buy an additional 681,818 shares.
Twist Bioscience Corporation (NASDAQ: TWST) announced that CEO Emily M. Leproust and CFO Jim Thorburn will participate in a fireside chat at the 11th Annual SVB Leerink Global Healthcare Conference on February 17 at 8:00 a.m. Eastern Time. The event will be webcast live, accessible through the Investor Calendar on the company’s website, with a replay available for 30 days. Twist Bioscience is a leader in synthetic biology, using a unique silicon-based DNA synthesis platform to produce synthetic DNA products across various industries, including healthcare and agriculture.
Twist Bioscience Corporation (NASDAQ: TWST) announced a public offering of up to $200 million in common stock, with an option for underwriters to purchase an additional $30 million. The offering's completion and terms are subject to market conditions. Proceeds will fund R&D for pharmaceutical biologics and DNA data storage, expand the commercial organization, and support NGS operations. The offering is registered with the SEC under Form S-3. J.P. Morgan, Goldman Sachs, Cowen, and William Blair are acting as joint managers.
Twist Bioscience (NASDAQ: TWST) and C2i Genomics have partnered to develop whole-genome cancer reference materials. This collaboration aims to enhance cancer diagnostics by creating standardized reference samples for labs, enabling better validation of whole-genome assays. C2i will utilize AI to identify cancer-associated genomic variants, which Twist will synthesize to form comprehensive reference kits. The initiative seeks to address the urgent need for validated materials in cancer detection and aims to improve accessibility and precision in oncology care worldwide.
Twist Bioscience (NASDAQ: TWST) and Eleven Therapeutics have developed a replicon tool to enhance the study of viral genome replication and advance antiviral drug screening, as well as vaccine and therapeutic development. The SARS-CoV-2 replicon retains 97% of the viral genome but eliminates its infectivity. This system can facilitate rapid therapeutic development and testing of drug efficacy against various variants. Twist has also established a biosafety committee to oversee related research, underscoring its commitment to safety in biotech innovation.
Twist Bioscience (NASDAQ: TWST) reported a strong first quarter of fiscal 2022, achieving record revenues of $42 million, a 49% increase from $28.2 million in fiscal 2021. Orders rose 48% to $49.6 million. R&D expenses increased to $22.6 million, while net loss widened to $45.6 million or $0.91 per share. The company's cash position stood at $408.7 million. Key developments included collaborations in biopharma and the introduction of new products for liquid biopsy and DNA data storage solutions.
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