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Tevogen Bio Holdings Inc. (Nasdaq: TVGN) is a clinical-stage specialty immunotherapy company, leveraging the power of CD8+ cytotoxic T lymphocytes (CTLs) to develop off-the-shelf, precision T cell therapies aimed at treating infectious diseases, cancers, and neurological disorders. Founded in 2020, Tevogen Bio has made significant strides in a short period, thanks to its highly cost-efficient business model and rapid technological advancements.
Tevogen Bio's core technology, ExacTcell™, harnesses the natural capabilities of CTLs to target and eliminate disease-causing cells. This platform is genetically unmodified, ensuring an allogeneic approach that is both flexible and scalable. The company's commitment to innovation is further exemplified by its integration of artificial intelligence to optimize the development of these therapies.
One of Tevogen Bio’s leading products, TVGN 489, focuses on treating COVID-19 and Long COVID. The company has reported positive safety data from its proof-of-concept clinical trials and is preparing for subsequent phases. TVGN 489 targets multiple proteins of SARS-CoV-2, maintaining effectiveness across various strains, including the highly mutated FLiRT variants.
Tevogen Bio's oncology pipeline is also noteworthy. Their CTLs are being explored for use in virally driven cancers such as cervical cancer caused by the Human Papilloma Virus (HPV). This strategy could provide a less invasive alternative to current surgical methods and potentially enhance the efficacy of combined treatments.
Financially, Tevogen Bio is backed by notable investors who have shown strong confidence in its commercial potential. Recent agreements have secured up to $50 million in financing, aimed at bolstering research and development, expanding clinical trials, and enhancing manufacturing capabilities. The company has successfully eliminated $94.9 million in balance sheet liabilities through strategic conversions of promissory notes into common stock.
Leadership at Tevogen Bio consists of experienced industry professionals and distinguished scientists dedicated to advancing personalized therapeutic solutions. Their vision is to ensure patient accessibility to advanced treatments through innovative business models and sustainable practices.
Tevogen Bio (Nasdaq: TVGN) has secured a non-dilutive grant agreement with KRHP for up to $10 million in funding. The company received an initial contribution of $2 million, with an additional $8 million potentially available subject to KRHP's review of company activities. This grant follows a previously announced $36 million loan agreement from 2Q24.
The funding will support Tevogen's development of T cell therapeutics for cancer and viral infection treatments, as well as expand its artificial intelligence initiative, Tevogen.AI. The company is collaborating with Microsoft and recently hosted two panels at the JPMorgan Healthcare Conference, focusing on AI applications in biopharma.
Dr. Ryan Saadi, Chairman and CEO of Tevogen Bio (Nasdaq: TVGN), a clinical-stage specialty immunotherapy biotech, has extended congratulations to Lynne Patton on her appointment as Deputy Assistant to the President and Director of Minority Outreach. Ms. Patton will join the Office of Public Liaison, focusing on building support among Blacks, Latinos, and Women.
Patton previously served as Regional Administrator for Federal Region II at HUD and Senior Advisor to Secretary Ben Carson, where she worked on housing reform and accountability. In her new role, she will lead outreach efforts to minority communities.
Dr. Saadi emphasized Tevogen Bio's commitment to supporting presidential initiatives for affordable medical innovation, stating that business success should contribute to societal prosperity.
Tevogen Bio (Nasdaq: TVGN) has expanded its collaboration with Microsoft (Nasdaq: MSFT) to enhance its AI capabilities and develop PredicTcell technology on Azure. This expansion builds upon their previous Microsoft for Startups program participation.
The collaboration focuses on two key objectives: accelerating the ExacTcell™ technology pre-clinical pipeline through machine learning simulations for target identification, and developing proprietary algorithms to decode HLA-T cell interactions. The partnership leverages Microsoft's AI tools, cloud capabilities, and health sciences expertise.
Additionally, Tevogen Bio is utilizing Microsoft Azure and AI tools to investigate potential Human Papillomavirus (HPV) treatments. The company is developing TVGN 920, its first oncology product candidate, by identifying cytotoxic T cell targets from HPV genome proteins using their proprietary ExacTcell™ technology.
Tevogen Bio (Nasdaq: TVGN) shared insights from a fireside chat with Microsoft during the J.P. Morgan Healthcare Conference, focusing on AI-driven drug development. The discussion featured Microsoft's Global Chief Medical Officer Dr. David Rhew and Tevogen's CIO Mittul Mehta, head of Tevogen.AI.
The speakers highlighted how AI and machine learning are revolutionizing drug discovery, with AI-powered tools reducing computational tasks from thousands of years to months. They emphasized the importance of multimodal data AI, which processes diverse data sources including imaging, genomics, and health records.
Tevogen Bio is developing curated datasets for reliable AI models, while emphasizing data governance and privacy-preserving techniques. The company's AI initiatives align with its commitment to patient equity, aiming to achieve cost and time efficiencies that could result in patient savings.
Tevogen Bio (Nasdaq: TVGN) announced it will host two panel discussions at the 43rd Annual J.P. Morgan Healthcare Conference in San Francisco on January 13, 2025. The first panel, 'AI In Biopharma: Next Frontier of Medical Innovation', will explore how AI technologies can revolutionize drug discovery, accelerate development, and reduce costs. The second panel, 'Pioneering the Economics of Health: Balancing Access and Outcomes', will examine healthcare ecosystem interdependencies.
Notable panelists include Microsoft's Global Chief Medical Officer David Rhew, Rubix Health's Sean Tunis, Simon-Kucher's Peter Ehrhardt, and former VA Acting Under Secretary Poonam Alaigh. The event will be held at the Marines' Memorial Club & Hotel, featuring panel discussions from 2:00 PM to 4:00 PM PST, followed by a reception.
Tevogen Bio (Nasdaq: TVGN) announced it will host an AI panel during the 43rd Annual J.P. Morgan Healthcare Conference in San Francisco. The panel, titled 'AI in Biopharma: Next Frontier of Medical Innovation,' will feature speakers from Microsoft and Tevogen.AI discussing how artificial intelligence can transform drug discovery, development timelines, patient accessibility, and reduce operating costs.
The event will take place on January 13, 2025, at the Marines' Memorial Club & Hotel, featuring panelists including Microsoft's Global Chief Medical Officer Dr. David Rhew, Tevogen.AI's CIO Mittul Mehta, and Rubix Health's Dr. Sean Tunis. The session will highlight Tevogen.AI's use of advanced AI capabilities in developing precision T cell therapies for infectious diseases, cancers, and neurological disorders.
Tevogen Bio (Nasdaq: TVGN) has filed a new patent titled 'Systems And Methods For Predicting Immunologically Active Peptides With Machine Learning Models' to strengthen its IP portfolio. The company launched Tevogen.AI in October 2023 to enhance drug discovery, development, and manufacturing processes. Key developments include:
- Appointment of Mittul Mehta to lead Tevogen.AI
- Partnership with Microsoft through the Microsoft for Startups program in May 2024
- Successful application of machine learning for HPV target identification in November 2024
- Filing of International Application PCT/US2024/060419 on December 16, 2024
The company's ExacTcell™ technology aims to create CTL products targeting various viruses. Tevogen plans to provide additional updates at the J.P. Morgan Healthcare Conference in January 2025.
Tevogen Bio (Nasdaq: TVGN) announced it will host a panel discussion titled 'Pioneering the Economics of Health: Balancing Access and Outcomes' during the 43rd Annual J.P. Morgan Healthcare Conference. The event, scheduled for January 13, 2025, will be held at the Marines' Memorial Club & Hotel in San Francisco.
The panel will feature distinguished healthcare leaders discussing critical aspects of the healthcare ecosystem, including:
- U.S. leadership challenges in healthcare innovation
- Impact of cost-containment measures and the Inflation Reduction Act
- Implications of new administration's healthcare approach on global markets
Panelists include executives from Simon-Kucher, Department of Veterans Affairs, Rubix Health, Tufts Center, and Tevogen Bio leadership. The discussion will run from 3:15 PM to 4:00 PM PST, followed by a reception until 6:00 PM.
Tevogen Bio (Nasdaq: TVGN), a clinical-stage specialty immunotherapy biotech company, has announced its participation in the 43rd Annual J.P. Morgan Healthcare Conference. The conference, scheduled for January 13-16, 2025, in San Francisco, will be attended by Tevogen's Founder and CEO Ryan Saadi, MD, MPH.
The company, which specializes in developing off-the-shelf, genetically unmodified T cell therapeutics for infectious diseases and cancers, will be part of what is recognized as the industry's largest and most informative healthcare investment symposium. The event brings together key stakeholders to discuss healthcare innovations and advancements.
Victor Sordillo, Board Member of Tevogen Bio (Nasdaq: TVGN), has been inducted into The New Jersey League of Municipalities Hall of Fame for his 24 years of continuous service as Warren Township Committee Member. During his tenure as Mayor, Warren Township achieved significant developments including the construction of a new library, town hall, youth facilities, and the acquisition of approximately 1,000 acres of open space.
Under his leadership, Warren Township maintained a AAA bond rating while keeping long-term debt at one-tenth of the state-allowable limit. The township received notable recognition, being ranked sixth best place to live in America by Money magazine and second-best place to live in Central NJ by New Jersey Monthly.
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