Tiziana Life Sciences Announces Presentations on Intranasal Foralumab at the “Preserving the Brain” Scientific Conference and Exhibit at Prada Rong Zhai in Shanghai

Rhea-AI Summary

Tiziana Life Sciences Ltd. (Nasdaq: TLSA) announced poster presentations on its lead asset, intranasal foralumab, at the "Preserving the Brain" scientific conference in Shanghai, running from March 31 to May 21, 2023. The event aims to foster discussions on neurodegenerative diseases among international experts. Gabriele Cerrone, Executive Chairman of Tiziana, expressed enthusiasm for foralumab's presentation, highlighting it as the only fully human anti-CD3 monoclonal antibody. Foralumab modulates T cell function which may aid in treating inflammatory conditions. Phase 2 trials for intranasal foralumab in patients with non-active SPMS are anticipated to begin in Q3 2023.

Positive

• Intranasal foralumab is the only fully human anti-CD3 monoclonal antibody, indicating potential exclusivity in the market.
• The upcoming Phase 2 trials for non-active SPMS patients are set to commence in Q3 2023, which could validate the therapy's effectiveness.
• Participation in a prominent scientific conference enhances foralumab's visibility and credibility among international researchers.

Negative

• None.

• Exhibition will run from March 31^st to May 21^st, 2023, at Prada Rong Zhai
• Scientific Conference will be held on April 20^th, 2023, at Prada Rong Zhai

NEW YORK, April 10, 2023 (GLOBE NEWSWIRE) -- Tiziana Life Sciences Ltd. (Nasdaq: TLSA) (“Tiziana” or the “Company”), a biotechnology company developing breakthrough immunomodulation therapies via novel routes of drug delivery, today announced that poster presentations on intranasal foralumab are being presented at the “Preserving the Brain” scientific conference and exhibit held at the Fondazione Prada in Rong Zhai in Shanghai.

“Preserving the Brain” is a scientific forum and exhibit on neurodegenerative diseases as part of the “Human Brains” neuroscience project held in Fondazione Prada in Shanghai, China. In collaboration with thirteen of the most relevant international neuroscience institutes and universities, the aim of this event is to stimulate an open and critical exchange between international scientists and experts on neurodegenerative diseases.

“I am absolutely thrilled that foralumab has once again been invited to be presented at the Fondazione Prada’s “Preserving the Brain” international forum, this year being held in Shanghai,” commented Gabriele Cerrone, Executive Chairman and interim Chief Executive Officer of Tiziana Life Sciences. “Having our lead asset Foralumab, the only fully human anti-CD3 highlighted again at an esteemed cultural institution such as Fondazione Prada only further validates our passion and focus to advance this novel therapy in neuroinflammatory diseases.”

About Foralumab

Activated T cells play an important role in the inflammatory process. Foralumab, the only fully human anti-CD3 monoclonal antibody (mAb), binds to the T cell receptor and dampens inflammation by modulating T cell function, thereby suppressing effector features in multiple immune cell subsets. This effect has been demonstrated in patients with COVID and with multiple sclerosis, as well as in healthy normal subjects. Intranasal foralumab Phase 2 trials are expected to start in the third quarter of 2023 in patients with non-active SPMS. Immunomodulation by nasal anti-CD3 mAb represents a novel avenue for treatment of inflammatory human diseases.¹

About Tiziana Life Sciences

Tiziana Life Sciences is a clinical-stage biopharmaceutical company developing breakthrough therapies using transformational drug delivery technologies to enable alternative routes of immunotherapy. Tiziana’s innovative nasal, oral and inhalation approaches in development have the potential to provide an improvement in efficacy as well as safety and tolerability compared to intravenous (IV) delivery. Tiziana’s lead candidate, intranasal foralumab, which is the only fully human anti-CD3 mAb, has demonstrated a favorable safety profile and clinical response in patients in studies to date. Tiziana’s technology for alternative routes of immunotherapy has been patented with several applications pending and is expected to allow for broad pipeline applications.

For further inquiries:

Tiziana Life Sciences Ltd

Paul Spencer, Business Development and Investor Relations
+44 (0) 207 495 2379
email: info@tizianalifesciences.com

Investors:
Irina Koffler
LifeSci Advisors, LLC
646.970.4681
ikoffler@lifesciadvisors.com

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¹ https://www.pnas.org/doi/10.1073/pnas.2220272120

 

FAQ

What are the key dates for Tiziana Life Sciences' exhibition and conference events?

The exhibition runs from March 31 to May 21, 2023, and the scientific conference is on April 20, 2023.

What is intranasal foralumab and its relevance?

Intranasal foralumab is a fully human anti-CD3 monoclonal antibody that modulates T cell function, relevant for treating inflammation.

When will the Phase 2 trials for intranasal foralumab start?

Phase 2 trials are expected to begin in the third quarter of 2023.

What is the significance of the 'Preserving the Brain' conference for Tiziana Life Sciences?

The conference allows Tiziana to showcase foralumab, enhancing its reputation and fostering scientific collaboration.