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TCBP Announces Artificial Intelligence Initiative with Partner Carnegie Mellon University for Donor Screening

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TC BioPharm (NASDAQ: TCBP) has announced a partnership with Carnegie Mellon University to develop an artificial intelligence solution for optimizing donor screening and matching processes in cell therapy. The company will collaborate with Dr. Wei Wu from the Ray and Stephanie Lane Computational Biology Department to leverage AI in addressing the 'big data problem' of donor variability and patient matching.

The initiative aims to enhance manufacturing yields, improve production processes, and potentially boost patient outcomes. Bryan Kobel, CEO of TC BioPharm, emphasized the significance of this partnership in advancing the cell therapy industry and addressing challenges beyond current HLA matching processes. Dr. Wu highlighted the potential of AI to transform precision medicine and personalized cell therapies.

TC BioPharm (NASDAQ: TCBP) ha annunciato una partnership con Carnegie Mellon University per sviluppare una soluzione di intelligenza artificiale per ottimizzare i processi di screening e di abbinamento dei donatori nella terapia cellulare. L'azienda collaborerà con Dr. Wei Wu del Dipartimento di Biologia Computazionale Ray e Stephanie Lane per sfruttare l'IA nell'affrontare il 'problema dei big data' relativo alla variabilità dei donatori e all'abbinamento con i pazienti.

L'iniziativa mira a migliorare i rendimenti produttivi, ottimizzare i processi di produzione e potenzialmente migliorare i risultati per i pazienti. Bryan Kobel, CEO di TC BioPharm, ha sottolineato l'importanza di questa partnership per far progredire l'industria della terapia cellulare e affrontare le sfide oltre i processi di abbinamento HLA attuali. Il Dr. Wu ha evidenziato il potenziale dell'IA di trasformare la medicina di precisione e le terapie cellulari personalizzate.

TC BioPharm (NASDAQ: TCBP) ha anunciado una asociación con Carnegie Mellon University para desarrollar una solución de inteligencia artificial que optimice los procesos de selección y coincidencia de donantes en la terapia celular. La empresa colaborará con Dr. Wei Wu del Departamento de Biología Computacional Ray y Stephanie Lane para aprovechar la IA en la resolución del 'problema de los grandes datos' relacionado con la variabilidad de los donantes y la coincidencia con los pacientes.

La iniciativa tiene como objetivo mejorar los rendimientos de fabricación, optimizar los procesos de producción y potencialmente aumentar los resultados para los pacientes. Bryan Kobel, CEO de TC BioPharm, enfatizó la importancia de esta asociación para avanzar en la industria de la terapia celular y abordar desafíos más allá de los procesos actuales de coincidencia HLA. El Dr. Wu destacó el potencial de la IA para transformar la medicina de precisión y las terapias celulares personalizadas.

TC BioPharm (NASDAQ: TCBP)는 카네기 멜론 대학교와 파트너십을 체결하고 세포 치료에서 기증자 선별 및 매칭 프로세스를 최적화하기 위한 인공지능 솔루션을 개발한다고 발표했습니다. 회사는 Ray와 Stephanie Lane 컴퓨터 생물학 부서의 Dr. Wei Wu와 협력하여 기증자 변동성과 환자 매칭의 '빅데이터 문제'를 해결하기 위해 AI를 활용할 것입니다.

이 이니셔티브는 제조 수율을 향상하고 생산 프로세스를 개선하며 잠재적으로 환자 결과를 향상시키는 것을 목표로 합니다. TC BioPharm의 CEO인 Bryan Kobel은 이 파트너십의 중요성이 세포 치료 산업을 발전시키고 현재의 HLA 매칭 프로세스를 넘어서는 문제들을 해결하는 데 있음을 강조했습니다. Dr. Wu는 AI가 정밀 의학과 개인 맞춤형 세포 치료를 혁신할 수 있는 잠재력을 강조했습니다.

TC BioPharm (NASDAQ: TCBP) a annoncé un partenariat avec Carnegie Mellon University pour développer une solution d'intelligence artificielle visant à optimiser les processus de sélection et de correspondance des donneurs dans la thérapie cellulaire. L'entreprise collaborera avec Dr. Wei Wu du Département de Biologie Computationnelle Ray et Stephanie Lane pour tirer parti de l'IA afin de résoudre le 'problème des big data' lié à la variabilité des donneurs et à la correspondance des patients.

Cette initiative vise à améliorer les rendements de fabrication, à optimiser les processus de production et à potentiellement améliorer les résultats pour les patients. Bryan Kobel, PDG de TC BioPharm, a souligné l'importance de ce partenariat pour faire progresser l'industrie de la thérapie cellulaire et relever des défis au-delà des processus actuels d'appariement HLA. Le Dr. Wu a mis en avant le potentiel de l'IA pour transformer la médecine de précision et les thérapies cellulaires personnalisées.

TC BioPharm (NASDAQ: TCBP) hat eine Partnerschaft mit der Carnegie Mellon University angekündigt, um eine Künstliche Intelligenz Lösung zur Optimierung der Spenderauswahl und -zuordnung in der Zelltherapie zu entwickeln. Das Unternehmen wird mit Dr. Wei Wu aus der Abteilung für Rechnergestützte Biologie Ray und Stephanie Lane zusammenarbeiten, um KI zu nutzen, um das 'Big Data Problem' der Spendervariabilität und der Patientenübereinstimmung zu adressieren.

Die Initiative zielt darauf ab, die Produktionsausbeuten zu verbessern, die Produktionsprozesse zu optimieren und potenziell die Patientenergebnisse zu steigern. Bryan Kobel, CEO von TC BioPharm, betonte die Bedeutung dieser Partnerschaft für den Fortschritt in der Zelltherapiebranche und die Bewältigung von Herausforderungen, die über die aktuellen HLA-Zuordnungen hinausgehen. Dr. Wu hob das Potenzial von KI hervor, die Präzisionsmedizin und personalisierte Zelltherapien zu transformieren.

Positive
  • Partnership with prestigious Carnegie Mellon University for AI development
  • Potential to optimize donor selection and patient matching processes
  • Possible improvements in manufacturing yields and production processes
  • Addressing a significant industry-wide challenge in cell therapy
Negative
  • None.

Insights

This partnership between TC BioPharm and Carnegie Mellon University to develop an AI-driven donor screening and matching solution is a significant step forward in addressing key challenges in cell therapy. The initiative aims to tackle donor variability and optimize patient-donor matching, which could lead to:

  • Improved manufacturing yields and production processes
  • Enhanced patient outcomes
  • Potential cost reductions in cell therapy production
  • Broader applications across the cell therapy industry

While promising, it's important to note that this is an early-stage research project. The actual impact on TCBP's financials and operations may not be immediate. However, if successful, this AI solution could become a valuable asset for TCBP, potentially leading to:

  • Licensing opportunities to other biotech companies
  • Improved efficiency in TCBP's own cell therapy development
  • Enhanced competitive positioning in the allogeneic cell therapy market

Investors should monitor the progress of this initiative, as successful development could significantly enhance TCBP's value proposition in the long term.

The collaboration between TC BioPharm and Carnegie Mellon University represents a strategic move to leverage AI in addressing complex challenges in cell therapy. Key points to consider:

  • The application of AI to donor screening and matching is a novel approach in the cell therapy field
  • This initiative targets a "big data problem," which is where AI typically excels
  • The potential for improved donor selection and patient matching could lead to more personalized and effective cell therapies

However, it's important to understand that AI projects in healthcare often face hurdles:

  • Regulatory challenges in implementing AI solutions in clinical settings
  • The need for extensive validation and clinical trials to prove efficacy
  • Potential issues with data privacy and security

While the long-term potential is significant, investors should be aware that the development and implementation of such AI solutions can be a lengthy process. The success of this initiative could position TCBP as an innovator in the cell therapy space, but it's important to maintain realistic expectations about the timeline for tangible results.

  • TC BioPharm Limited is partnering with Dr. Wei Wu of Carnegie Mellon University to create an artificial intelligence solution to optimize the donor screening and matching process
  • The software could have additional applications across cell therapy for donor/patient matching

EDINBURGH, Scotland, Oct. 3, 2024 /PRNewswire/ -- TC BioPharm (Holdings) PLC ("TC BioPharm" or the "Company") (NASDAQ: TCBP), a clinical-stage biotechnology company developing platform allogeneic gamma-delta T cell therapies for cancer and other indications, today announced it has entered into a sponsored research agreement with Carnegie Mellon University to explore the potential use of artificial intelligence to optimize the patient screening process.

The Company will partner with Dr. Wei Wu, a faculty member in the Ray and Stephanie Lane Computational Biology Department within the School of Computer Science at the renowned university, and her lab to leverage AI to build a solution that enhances the donor selection process and matching process. Dr. Wu's research focuses on understanding complex human diseases through integrative approaches, combining biology, computational and statistical learning, bioinformatics, and genomics. The applications for advanced and accurate donor screening and potential donor/patient matching extend from increased manufacturing yields, better production processes, and enhanced patient outcomes among many other benefits. The amount of variability between donors, similar patients, and the volume of donors and patients across diseases represents a "big data problem" which is ideal for applying Artificial Intelligence for a better understanding and potential solution.

"TC BioPharm is pleased to partner with Carnegie Mellon University as we continue to research cutting-edge solutions for the advancement of the cell therapy industry," stated Bryan Kobel, CEO of TC BioPharm. "Dr. Wu and her laboratory are helping us tackle another 'big problem' with this endeavor, which has the potential to revolutionize both the donor selection and matching processes. An issue the cell therapy industry faces as a whole is donor variability as well as how to more accurately predict outcomes and responses between donors and patients. Finding a solution for how to select the best donors for allogeneic cell therapies to generate the best product, and also how to match the best cell therapy and donor to the best patient beyond the current HLA matching process, represents a massive opportunity from a market perspective and also would have far-reaching applications for CDMOs and other industry players. Bringing in Dr. Wu for this 'big data problem' is the first step. She and Carnegie Mellon University are at the forefront of the AI industry, and it's an honor to work with her and the esteemed university. Artificial intelligence has the potential to deliver significant breakthroughs in the worlds of medicine and science, and we are excited to embrace its possibilities."

Dr. Wei Wu added, "I am excited about this partnership with TC BioPharm. With the integration of cutting-edge AI technology into cell therapy research, this collaboration holds a lot of promise for advancing the field and addressing key challenges such as donor variability. Optimizing donor selection and donor/patient pairing with AI could lead to solutions to some of the most pressing challenges in cell therapy, with the potential to improve patient outcomes. I'm excited that our team will be part of this effort. Given the significant potential of AI to transform industries, this partnership could open new doors for precision medicine and personalized cell therapies."

Forward-Looking Statements

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements contained in this Current Report on Form 8-K that do not relate to matters of historical fact should be considered forward-looking statements, including without limitation statements regarding the Company's intent or ability to affect any budget savings or execute on any M&A or capital raising strategy. These statements are based on management's current assumptions and are neither promises nor guarantees, but involve known and unknown risks, uncertainties and other important factors that may cause the Company's actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements. For other important factors that could cause actual results to differ materially from the forward-looking statements in this Current Report on Form 8-K, please see the risks and uncertainties identified under the heading "Risk Factors" in our Annual Report on Form 10-K for the year ended December 31, 2023, and our other reports filed with the SEC, all of which is available on the Company's Investor Relations website at www.tcbiopharm.com and on the SEC website at www.sec.gov. All forward-looking statements reflect the Company's beliefs and assumptions only as of the date of this Current Report on Form 8-K. The Company undertakes no obligation to update forward-looking statements to reflect future events or circumstances.

About TC BioPharm (Holdings) PLC

TC BioPharm is a clinical-stage biopharmaceutical company focused on the discovery, development, and commercialization of gamma-delta T cell therapies for the treatment of cancer with human efficacy data in acute myeloid leukemia. Gamma-delta T cells are naturally occurring immune cells that embody properties of both the innate and adaptive immune systems and can intrinsically differentiate between healthy and diseased tissue.

TC BioPharm is the leader in developing gamma-delta T cell therapies, and the first company to conduct phase II/pivotal clinical studies in oncology. The Company is conducting two investigator-initiated clinical trials for its unmodified gamma-delta T cell product line - Phase 2b/3 pivotal trial in treatment of acute myeloid leukemia using the Company's proprietary allogeneic CryoTC technology to provide frozen product to clinics worldwide.

Cision View original content:https://www.prnewswire.com/news-releases/tcbp-announces-artificial-intelligence-initiative-with-partner-carnegie-mellon-university-for-donor-screening-302265858.html

SOURCE TC BioPharm

FAQ

What is the purpose of TCBP's partnership with Carnegie Mellon University?

TCBP is partnering with Carnegie Mellon University to develop an artificial intelligence solution for optimizing donor screening and matching processes in cell therapy, aiming to improve manufacturing yields, production processes, and potentially enhance patient outcomes.

Who is the lead researcher from Carnegie Mellon University working with TCBP?

Dr. Wei Wu, a faculty member in the Ray and Stephanie Lane Computational Biology Department within the School of Computer Science at Carnegie Mellon University, is leading the research collaboration with TCBP.

How could AI benefit the cell therapy industry according to TCBP's announcement?

According to TCBP, AI could help address donor variability, improve donor selection for allogeneic cell therapies, enhance donor-patient matching beyond current HLA processes, and potentially revolutionize the cell therapy industry by solving 'big data problems'.

What are the potential applications of the AI solution being developed by TCBP and Carnegie Mellon?

The AI solution being developed could have applications in optimizing donor screening, improving donor-patient matching, enhancing manufacturing yields, refining production processes, and potentially improving patient outcomes in cell therapy treatments.

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