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Comprehensive Overview of SciSparc Ltd (SPRC)
SciSparc Ltd is a specialty clinical‐stage pharmaceutical company that leverages cutting‐edge cannabinoid technologies to develop innovative immunotherapy products and address central nervous system disorders. At its core, SciSparc focuses on the development of therapies derived from cannabinoid molecules, incorporating advanced biotechnology, immunotherapy, and clinical research methodologies. This dual‐focused enterprise operates across two distinct segments: one dedicated to clinical drug development and regulatory pathways, and another which drives the online sale of hemp-based consumable products.
Clinical-Stage Drug Development
The company’s primary business revolves around its clinical-stage drug development programs. SciSparc employs a portfolio based on both THC and non-psychoactive CBD compounds to create novel treatments for disorders such as Tourette Syndrome, Alzheimer’s disease with agitation, autism spectrum disorder, and status epilepticus. Utilizing a rigorous, research-driven approach, the company undertakes controlled clinical trials designed to evaluate drug efficacy, safety, and tolerability. With its IND applications and approvals for advanced clinical programs, SciSparc demonstrates its commitment to meeting stringent regulatory standards and addressing unmet medical needs in its target therapeutic areas.
Innovative Technology and Intellectual Property
SciSparc’s market positioning is strengthened by its robust portfolio of patents and proprietary technologies. The company’s innovations in cannabinoid pharmaceuticals are not only geared towards improving treatment outcomes but also distinguishing its offerings from traditional therapies. By investing in advanced research platforms, including computational drug discovery and predictive artificial intelligence models, SciSparc is able to screen and identify promising molecular candidates for further development. This technological prowess, combined with a clear focus on regulatory compliance and scientific excellence, forms the backbone of its strategic differentiation.
Online Sales and Hemp-Based Consumer Products
In addition to its core clinical operations, SciSparc diversifies its business model through a reportable segment that manages the online sale of a wide range of hemp-derived products. These products, which include hemp gummies, oil capsules, topical gels, creams for beauty and hair treatments, and other nutraceutical items, are manufactured domestically in the United States. This segment not only leverages SciSparc’s expertise in cannabinoid science but also capitalizes on the growing consumer demand for hemp-based nutritional and wellness products.
Strategic Positioning in a Competitive Landscape
SciSparc operates in a competitive and dynamic landscape where rigorous clinical research, robust intellectual property protection, and diversified revenue streams are critical. The company’s dual approach—pursuing breakthrough therapies through detailed clinical trials while also serving a broad consumer market with hemp-based products—allows it to mitigate risk and explore multiple avenues for value creation. By maintaining adherence to high standards of scientific inquiry and regulatory diligence, SciSparc reinforces its position as a trusted and innovative entity within the pharmaceutical and nutraceutical industries.
Expertise, Experience, and Trustworthiness
The expertise demonstrated by SciSparc’s team of senior executives and scientists adds a further layer of credibility to its endeavors. The company’s rigorous research protocols, combined with its strategic investments in cutting-edge technology and regulatory expertise, underscore its commitment to scientific excellence and long-term value creation. This methodical, research-intensive approach not only builds trust among stakeholders but also serves as a foundation for advancing next-generation therapies in areas that have long presented clinical challenges.
Conclusion
In summary, SciSparc Ltd exemplifies a forward-thinking pharmaceutical enterprise that effectively blends innovative drug development with consumer-oriented online sales. Its robust portfolio in cannabinoid-based immunotherapies, supported by extensive intellectual property and strategic clinical trials, positions it uniquely within a competitive market landscape. Whether addressing central nervous system disorders or fulfilling the growing consumer demand for hemp products, SciSparc’s dual business model represents a comprehensive and balanced approach to modern pharmaceutical innovation.
SciSparc (Nasdaq: SPRC) and Clearmind Medicine have achieved a significant milestone with the publication of their patent application in South Korea for a novel cocaine addiction treatment. The therapy combines Clearmind's MEAI (5-methoxy-2-aminoindane) with SciSparc's PEA (Palmitoylethanolamide).
The patent application is supported by promising preclinical trial results from Bar-Ilan University's Gonda Multidisciplinary Brain Research Center. The research demonstrated that MEAI significantly reduced cocaine-induced craving in animal subjects without affecting their natural reward responses, such as sucrose seeking behavior. This suggests the treatment specifically targets drug-related compulsions while preserving normal reward mechanisms.
This South Korean patent application adds to the companies' existing intellectual property portfolio, which includes multiple applications filed in the United States and other global territories.
SciSparc (Nasdaq: SPRC) has signed a definitive agreement to sell its entire 52.73% ownership stake in MitoCareX Bio , a cancer therapeutics drug discovery company, to N2OFF Inc. (Nasdaq: NITO). The transaction includes:
- $700,000 cash payment for 4,961 MitoCareX shares
- Exchange of remaining shares for 40% of N2OFF's fully diluted capital stock
- Potential additional N2OFF stock up to 25% based on milestones
- 30% share of N2OFF's financing proceeds over 5 years (max $1.6M)
- N2OFF's commitment to invest $1M in MitoCareX post-closing
The deal requires N2OFF shareholder approval and must close within 30 days. Dr. Alon Silberman will continue as CEO with a 5% restricted stock grant vesting over 3 years. Upon completion, MitoCareX will become a wholly-owned subsidiary of N2OFF.
SciSparc (Nasdaq: SPRC) has provided a new $2 million loan to AutoMax Motors to support its business expansion in direct importing of JAC electric vehicles. The loan carries an 8% annual interest rate, repayable in monthly installments of $50,000 plus interest, with an early repayment option without penalties.
This new funding follows previous bridge loans totaling $4.25 million provided as part of a merger agreement signed in April 2024. The interest will be cancelled upon merger completion, with AutoMax continuing principal payments. The loan is secured by a first-ranking fixed charge on AutoMax's subsidiary shares.
The merger agreement, signed in April 2024, will see SciSparc acquire 100% of AutoMax, marking its expansion into the automotive sector. The deal remains subject to customary closing conditions and shareholder approvals from both companies.
SciSparc (Nasdaq: SPRC) has reached a significant settlement agreement regarding a lawsuit it filed in February 2022 against six former directors. The settlement, approved through court-mediated negotiations, includes a $411,000 cash payment to SciSparc from the defendants.
The lawsuit alleged breaches of fiduciary duties under Israeli Companies Law related to a prior pain clinic network acquisition. A key component of the settlement is the termination of a disputed licensing agreement with Dekel Pharmaceuticals , effective February 5, 2024. This agreement had been established with the company's former chairman and CEO, Dr. Ascher Shmulewitz, in May 2015.
The settlement ensures SciSparc retains exclusive global rights to its IP portfolio, patents, know-how, and technologies, while being released from all commitments, claims, and royalties related to the License Agreement. Dekel will take ownership of patent applications for inflammatory disorder treatments, which are unrelated to SciSparc's current pipeline.
SciSparc (Nasdaq: SPRC) has announced a significant development in its collaboration with Clearmind Medicine Inc. (Nasdaq: CMND), as Clearmind secured a patent publication in Mexico for a novel combination treatment. The patent covers the innovative combination of MDMA with N-Acylethanolamines, targeting various binge behaviors including alcohol, eating, tobacco, shopping, and sexual conduct.
The treatment combines SciSparc's N-Acylethanolamines therapy with Clearmind's MEAI (5-methoxy-2-aminoindane). This collaborative research effort has resulted in 13 patent applications filed with the U.S. Patent and Trademark Office and other global jurisdictions, demonstrating the companies' commitment to developing new therapies for disorders and rare diseases of the central nervous system.
SciSparc (Nasdaq: SPRC), a clinical-stage pharmaceutical company focused on central nervous system disorders, has received a 180-day extension from Nasdaq until July 14, 2025 to regain compliance with the minimum bid price requirement. The company must achieve a closing bid price of at least $1.00 per share for a minimum of 10 consecutive business days to meet compliance.
This extension follows an initial notification from Nasdaq on July 16, 2024, which gave SciSparc 180 days until January 13, 2025, to meet the requirement. The company was granted the additional period after meeting all other Nasdaq Capital Market initial listing requirements except the bid price rule. SciSparc has indicated its intention to cure the deficiency, including the possibility of implementing a reverse share split if necessary.
The notification has no immediate impact on SciSparc's listing status, and its shares continue trading on the Nasdaq Capital Market under the symbol 'SPRC'.
SciSparc (Nasdaq: SPRC) announced that AutoMax Motors, with which it has a pending merger agreement, received its first $13 million shipment of vehicles from JAC Motors, a Chinese automotive manufacturer. This development follows regulatory approvals for direct importation in Israel and marks AutoMax's entry into direct import and distribution operations.
JAC Motors specializes in electric vehicles (EVs), offering both passenger and commercial vehicles supported by advanced R&D and battery technologies. AutoMax aims to leverage JAC's EV lineup to meet Israel's growing demand for sustainable transportation.
SciSparc has provided financial support to AutoMax to facilitate the JAC Motors transaction. The merger agreement between SciSparc and AutoMax, signed in April 2024, is subject to shareholders' approval from both companies and would enable SciSparc's expansion into the automotive sector.
SciSparc (Nasdaq: SPRC) announced that its joint venture MitoCareX Bio is expanding into pancreatic cancer research following positive initial in-vitro results. MitoCareX, which develops cancer therapeutics targeting the mitochondrial SLC25 protein family, has successfully identified potential anti-cancer treatments through its computational drug discovery platform that screened millions of small molecules.
The expansion adds pancreatic cancer to MitoCareX's existing research on non-small cell lung cancer. The company is also developing an AI model to analyze virtual data for discovering novel anti-cancer scaffolds. The announcement highlights that pancreatic cancer, with just a 12% five-year survival rate as of 2023, is the third leading cause of cancer-related deaths in the United States, representing a significant unmet medical need.
SciSparc (Nasdaq: SPRC) and Clearmind Medicine Inc. (Nasdaq: CMND) have announced the publication of a European patent application for a novel combination therapy treatment. The patent, filed by Clearmind, covers the combination of MEAI and N-Acylethanolamines for treating various binge behaviors, including alcohol consumption, eating, tobacco use, shopping, and sexual conduct.
The collaboration between the two companies focuses on developing innovative therapies combining psychedelic molecules with N-acylethanolamines, including Palmitoylethanolamide. To date, thirteen patents related to this collaboration have been filed by Clearmind across multiple global jurisdictions, including the United States.
SciSparc (SPRC) has received renewal approval from the Israeli Medical Cannabis Agency for its clinical trial of SCI-210 in children with autism spectrum disorder (ASD). The 30-day approval will be extended pending final approval from the Israeli police department. The trial is a double-blind, randomized, placebo-controlled study at Soroka University Medical Center, involving 60 children aged 5-18 with ASD.
The study will evaluate SCI-210, a combination of CBD and CannAmide™, against standard CBD monotherapy over a 20-week treatment period. Primary efficacy metrics include the ABC-C parent questionnaire and CGI-I scale. The company plans to initially commercialize SCI-210 in Israel before expanding internationally, subject to regulatory approvals.
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