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SELLAS Life Sciences Group, Inc. - SLS STOCK NEWS

Welcome to our dedicated page for SELLAS Life Sciences Group news (Ticker: SLS), a resource for investors and traders seeking the latest updates and insights on SELLAS Life Sciences Group stock.

SELLAS Life Sciences Group, Inc. (NASDAQ: SLS) is a late-stage clinical biopharmaceutical company dedicated to the development of novel therapeutics aimed at addressing a broad range of cancer indications. The company's core mission is to practice the medicine of tomorrow, today, by integrating innovative approaches that significantly impact the global healthcare landscape.

SELLAS' leading product candidate is galinpepimut-S (GPS), a peptide immunotherapy targeting the Wilms Tumor 1 (WT1) antigen. Licensed from Memorial Sloan Kettering Cancer Center, GPS is designed to treat various hematologic malignancies and solid tumors. Notably, GPS is currently undergoing a Phase 3 REGAL clinical trial for acute myeloid leukemia (AML), with promising safety and efficacy data observed so far.

Another pivotal asset in SELLAS' pipeline is SLS009 (formerly GFH009), a highly selective cyclin-dependent kinase 9 (CDK9) inhibitor. Licensed from GenFleet Therapeutics (Shanghai), Inc., SLS009 is being explored for its potential to treat relapsed/refractory acute myeloid leukemia (r/r AML) and other cancer types. Recent Phase 2a trial results show that SLS009 exhibits strong anti-leukemic activity, with favorable safety profiles and significant response rates, particularly in patients with identified biomarkers such as the ASXL1 mutation.

SELLAS is committed to advancing these therapeutics through rigorous clinical trials and strategic partnerships. The company collaborates with renowned scientists, healthcare professionals, and pharmaceutical executives to bring cutting-edge treatments to market. Recent collaborations include a clinical trial agreement with BeiGene Switzerland GmbH to study the combination of GFH009 and BRUKINSA® (zanubrutinib) in treating diffuse large B cell lymphoma (DLBCL).

Financially, SELLAS has shown resilience and growth, as evidenced by a successful $20 million registered direct offering in March 2024, bolstering their cash reserves for ongoing R&D activities. The company continues to report sound financial health, marked by a focused approach on strategic developments and clinical milestones.

For more information on SELLAS Life Sciences Group, Inc. and its innovative therapies, visit their official website at www.sellaslifesciences.com.

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SELLAS Life Sciences Group (NASDAQ: SLS) announced the final approval on November 19, 2021, by the United States District Court for the District of New Jersey regarding the settlement of claims related to its predecessor, Galena Biopharma, Inc.. This settlement resolves derivative actions Keller v. Ashton and Johnson v. Schwartz and mandates the adoption of new policies for future commercialization of clinical candidates. The company's insurer will cover attorney's fees up to $270,000. SELLAS focuses on developing cancer immunotherapies, with its lead product candidate, galinpepimut-S (GPS).

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SELLAS Life Sciences Group (NASDAQ: SLS) reported Q3 2021 financial results, including a net loss of $7.1 million and no licensing revenue for the quarter. R&D expenses rose to $4.5 million, significantly up from $2.4 million in Q3 2020, driven by clinical trial activities for the Phase 3 REGAL study of galinpepimut-S (GPS) in AML. The company is also planning a Phase 2/3 study for GPS in post-BMT AML patients. As of September 30, 2021, cash equivalents stood at approximately $26.3 million, indicating ongoing financial support for its clinical initiatives.

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SELLAS Life Sciences Group (NASDAQ: SLS), a biopharmaceutical company focused on cancer immunotherapies, announced that CEO Angelos Stergiou will participate in two key conferences. The first is the Laguna Biotech CEO Forum from October 10-12, 2021, in Laguna Beach, CA. The second is the A.G.P./Alliance Global Partners Biotech & Specialty Pharma Conference on October 13, 2021, which will be held virtually. SELLAS aims to advance its immunotherapeutic candidates, galinpepimut-S and nelipepimut-S, targeting various cancer indications.

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SELLAS Life Sciences Group, Inc. (NASDAQ: SLS) announced preliminary court approval for a settlement related to derivative claims against former executives of its predecessor, Galena Biopharma. The settlement includes a stipulation that mandates the company to implement specific policies concerning future commercialization of its clinical candidates. Furthermore, the company's insurer will cover up to $270,000 in legal fees. A final settlement approval hearing is scheduled for November 19, 2021.

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SELLAS Life Sciences Group, Inc. (NASDAQ: SLS) announced that CEO Angelos Stergiou will present at the 2021 Cantor Global Healthcare Conference on September 28, 2021, at 4:00 p.m. ET. The company specializes in developing innovative cancer immunotherapies, notably its lead candidate galinpepimut-S (GPS), which targets the WT1 protein in various tumors, and nelipepimut-S (NPS), aimed at early-stage breast cancer patients. For further details about the conference or to arrange meetings, interested parties can contact Cantor representatives or KCSA Strategic Communications.

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SELLAS Life Sciences Group (SLS) reported significant clinical updates on Galinpepimut-S (GPS), showcasing its potential in treating malignant pleural mesothelioma and WT1+ advanced ovarian cancer. The company highlighted results from a study showing an overall survival (OS) of 48.5 months for AML patients treated with GPS. Financially, SLS recorded licensing revenue of $1.9 million for Q2 2021, with a cash position of $29.9 million as of June 30, 2021. A virtual investor symposium is scheduled for August 17, 2021, to discuss further insights on GPS and its promising clinical data.

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SELLAS Life Sciences Group, a late-stage clinical biopharmaceutical company, will host a virtual investor symposium on August 17, 2021, focusing on its lead asset, galinpepimut-S (GPS). The event will detail GPS's clinical program and recent data regarding acute myeloid leukemia (AML) treatment. Notably, Dr. Yair Levy, a leading cancer researcher, will join the management team. GPS targets the WT1 protein in various tumors and has potential for treating hematologic malignancies and solid tumors.

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SELLAS Life Sciences Group (NASDAQ: SLS) reported encouraging results from its Phase 1/2 clinical trial of its lead immunotherapy, galinpepimut-S (GPS), combined with pembrolizumab for advanced ovarian cancer. Notably, 100% of patients are alive, and 45.5% continue with the treatment. CD8+ T-cell responses increased by an average of +242%, indicating robust immune activation. The disease control rate was 63.6%, with a median progression-free survival of 11.8 weeks in a challenging patient cohort. These findings suggest potential for GPS as a viable therapy in difficult-to-treat cases.

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SELLAS Life Sciences Group, Inc. (NASDAQ: SLS) announced promising results from a Phase 1 trial combining its lead candidate, galinpepimut-S (GPS), with nivolumab for treating malignant pleural mesothelioma (MPM). Patients showed a median overall survival of 35.4 weeks, compared to approximately 28 weeks with standard care. The combination therapy appears to provide significant clinical benefits, especially for patients who have failed traditional treatments. SELLAS plans to provide further clinical data by the end of Q4 2021.

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SELLAS Life Sciences Group (Nasdaq: SLS) announced its inclusion in the Russell Microcap Index, effective June 28, 2021. This inclusion is a significant milestone expected to enhance the company's visibility within the investment community. SELLAS, known for developing cancer immunotherapies, notably its lead candidate GPS, aims to provide treatment options for various cancer types. The Russell Microcap Index inclusion lasts for a year and is determined by market capitalization and style attributes, impacting approximately $10.6 trillion in assets.

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FAQ

What is the current stock price of SELLAS Life Sciences Group (SLS)?

The current stock price of SELLAS Life Sciences Group (SLS) is $0.9295 as of December 24, 2024.

What is the market cap of SELLAS Life Sciences Group (SLS)?

The market cap of SELLAS Life Sciences Group (SLS) is approximately 65.4M.

What does SELLAS Life Sciences Group, Inc. specialize in?

SELLAS Life Sciences Group, Inc. focuses on the development of novel therapeutics for a broad range of cancer indications.

What is GPS in SELLAS' product pipeline?

GPS, or galinpepimut-S, is a peptide immunotherapy targeting the WT1 antigen, designed to treat various cancers and currently in a Phase 3 clinical trial for AML.

What is SLS009?

SLS009 is a highly selective CDK9 inhibitor licensed from GenFleet Therapeutics, being tested for effectiveness in treating relapsed/refractory AML and other cancers.

How is SELLAS contributing to cancer research?

SELLAS advances cancer research through clinical trials of innovative therapies like GPS and SLS009, aiming to address unmet medical needs in oncology.

Who are SELLAS' key partners?

SELLAS collaborates with Memorial Sloan Kettering Cancer Center, GenFleet Therapeutics, and BeiGene Switzerland GmbH for its clinical trials and therapeutic developments.

What financial milestone did SELLAS achieve in 2024?

In March 2024, SELLAS completed a $20 million registered direct offering, enhancing their financial position for ongoing research and development activities.

What recent clinical trial advancements has SELLAS made?

SELLAS recently completed enrollment in the Phase 3 REGAL trial for GPS in AML and reported positive Phase 2a results for SLS009 in r/r AML.

What is the significance of the ASXL1 mutation in SELLAS' research?

The ASXL1 mutation is linked to poor prognosis in myeloid diseases, and SELLAS' SLS009 has shown promising response rates in patients with this mutation, indicating potential for targeted therapy.

Where can I get more information about SELLAS Life Sciences Group, Inc.?

For more details, visit SELLAS Life Sciences Group, Inc.'s official website at www.sellaslifesciences.com.

What is the focus of the collaboration between SELLAS and BeiGene Switzerland GmbH?

The collaboration focuses on a clinical trial combining GFH009 (CDK9 inhibitor) and BRUKINSA® (zanubrutinib, BTK inhibitor) to treat diffuse large B cell lymphoma.

SELLAS Life Sciences Group, Inc.

Nasdaq:SLS

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65.42M
70.26M
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13.39%
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