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Cellarity, a life sciences company, has announced several key leadership appointments to enhance its innovative drug discovery platform. John Leaman, M.D., M.B.A., joins as Chief Financial Officer, bringing extensive experience from Impel Pharmaceuticals, Selecta Biosciences, and Medgenics. Cameron Trenor, M.D., is appointed as Vice President and Head of Translational Medicine, with a strong background in hematology drug development. Anjali Kumar, Ph.D., takes on the role of Vice President, Head of Business Development, previously leading innovation at Johnson & Johnson. Additionally, Parul Doshi, M.B.A., has been promoted to Chief Data Officer. These changes aim to accelerate Cellarity's progress towards its clinical pipeline, leveraging its proprietary AI platform to create novel drug candidates for complex diseases.
On March 21, 2023, Selecta Biosciences (NASDAQ: SELB) reported positive topline results from its Phase 3 DISSOLVE I and II trials for SEL-212, an investigational treatment for chronic refractory gout. In DISSOLVE I, 56% of patients achieved a response at a high dose, significantly outperforming the placebo rate of 4%. DISSOLVE II showed a 47% response rate at the same dosage compared to 12% for placebo. The treatment demonstrated a 69% reduction in serum urate levels and maintained a favorable safety profile, with only 3.4% of patients experiencing infusion reactions. The company aims to file for U.S. marketing approval in the first half of 2024.