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Cassava Sciences, Inc. - SAVA STOCK NEWS

Welcome to our dedicated page for Cassava Sciences news (Ticker: SAVA), a resource for investors and traders seeking the latest updates and insights on Cassava Sciences stock.

Cassava Sciences, Inc. (NASDAQ: SAVA) is a clinical-stage biotechnology company dedicated to the development of innovative solutions for the treatment and detection of Alzheimer's disease. The company's primary focus is on two groundbreaking product candidates: simufilam and SavaDx.

Simufilam is an oral therapeutic designed to treat Alzheimer's disease. It is currently undergoing two randomized, placebo-controlled Phase 3 clinical trials to assess its efficacy in patients with Alzheimer's dementia. This novel treatment aims to improve cognitive function and slow down the progression of the disease.

SavaDx, the company's investigational diagnostic product, represents a significant advancement in the early detection of Alzheimer's disease. This innovative diagnostic tool can potentially identify the presence of Alzheimer's years before symptoms become apparent, using a small sample of blood.

In addition to its clinical trials, Cassava Sciences recently announced a major financial achievement. The company secured over $125 million from the exercise of warrants, reflecting strong investor confidence. These funds will support the ongoing development and potential commercialization of their innovative products.

Cassava Sciences' mission is to address the urgent unmet medical needs of Alzheimer's patients and their families through rigorous scientific research and development. With its dedicated team and promising product pipeline, the company is well-positioned to make a significant impact on the landscape of Alzheimer's treatment and diagnosis.

For the latest updates on Cassava Sciences’ projects, partnerships, and financial performance, investors can refer to the company's filings with the Securities and Exchange Commission (SEC). For more detailed information, contact Eric Schoen, Chief Financial Officer, at (512) 501-2450 or ESchoen@CassavaSciences.com.

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Cassava Sciences (Nasdaq: SAVA) has announced an expansion of its open-label extension trials for simufilam in Alzheimer's disease. The trials will be extended by up to 36 months, allowing patients who participated in randomized trials to continue treatment if desired. This extension bridges the gap between trial completion and Phase 3 results reporting.

Key points:

  • 89% of Phase 3 patients have chosen to continue open-label treatment
  • Cognition and plasma biomarker monitoring will be added to gather long-term data
  • Patients who completed the extension trial can now re-enroll
  • Two ongoing Phase 3 studies: RETHINK-ALZ (804 patients) and REFOCUS-ALZ (1,125 patients)
  • Top-line results expected by end of 2024 for RETHINK-ALZ and mid-2025 for REFOCUS-ALZ
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Cassava Sciences (Nasdaq: SAVA) has announced significant changes in its executive leadership and corporate governance. Rick Barry has been appointed as Executive Chairman and principal executive officer, replacing Remi Barbier, who has resigned as President, CEO, and from the Board. The company has initiated a search for a new permanent CEO.

Additionally, Lindsay Burns, Ph.D., SVP of Neuroscience, is leaving the company but will provide consulting services for a year. Cassava is implementing several initiatives to enhance transparency and accountability, including:

  • Separating Chairman and CEO roles
  • Commitment to scientific rigor and honest transparency
  • Ensuring integrity of clinical trial results
  • Improving communication with stakeholders

The company remains focused on developing a potential Alzheimer's treatment while adhering to high ethical standards.

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Cassava Sciences (Nasdaq: SAVA) announced that a federal grand jury indicted Dr. Hoau-Yan Wang, a former science advisor and tenured medical professor, for allegedly defrauding the U.S. National Institutes of Health (NIH). The indictment claims Dr. Wang engaged in illegal activities related to grant applications between 2017 and 2021, resulting in approximately $16 million in grants. These grants were connected to the early development phases of Cassava's drug candidate and diagnostic test. The company emphasized that Dr. Wang and his former university have no involvement in the Phase 3 clinical trials of simufilam, their lead drug candidate for Alzheimer's disease treatment.

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Cassava Sciences reported strong financial results for Q1 2024, with $126.3 million in total gross proceeds from warrants. Over 1,900 Alzheimer's patients are enrolled in Phase 3 trials of Simufilam, with positive clinical updates. Net income was $25.0 million, a significant improvement from a net loss of $24.3 million in 2023. Cash use for operations is expected to be $35 to $45 million for the first half of 2024.

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Cassava Sciences, a biotechnology company focused on Alzheimer's disease, announced over $125 million in gross proceeds from the cash-exercise of warrants, resulting in the issuance of approximately 5.7 million common shares at $22.00 per share. The net proceeds of over $123 million will be used for working capital and the development of their lead drug candidate, simufilam, for Alzheimer's treatment.

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May 2, 2024, is the last day to trade SAVAW warrants on NASDAQ, with May 6, 2024, being the final day to cash-exercise the warrants. Holders can use the Notice of Guaranteed Delivery for warrant exercises. Failure to exercise warrants by May 6 will result in redemption at a nominal price. Detailed information is available on the company's website.

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Cassava Sciences, Inc. announces the redemption date for warrants, with May 6, 2024, being the last day to exercise them. Holders will receive 1.5 shares of common stock per warrant, with a redemption price of $0.001 per warrant if not exercised by the deadline. The company urges holders to act promptly to avoid missing the deadline.
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Cassava Sciences, Inc. announces positive interim safety review of simufilam in Phase 3 trials for Alzheimer's disease treatment. DSMB recommends trials continue as planned. Final clinical safety data expected at program conclusion.
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Cassava Sciences to Present Oral Simufilam Data at AD/PD 2024 Conference
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Cassava Sciences, Inc. reported $121.1 million in cash and cash equivalents at December 31, 2023, with an additional $21.8 million raised in 2024. The company's Phase 3 studies have over 555 participants, with topline data readout expected year-end 2024. An internal investigation found no evidence of research misconduct. Net loss for 2023 was $97.2 million, with increased R&D and G&A expenses. Corporate highlights include dividend distribution, positive safety findings, new Board members, and biological activity confirmation of simufilam.
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FAQ

What is the current stock price of Cassava Sciences (SAVA)?

The current stock price of Cassava Sciences (SAVA) is $26.05 as of November 20, 2024.

What is the market cap of Cassava Sciences (SAVA)?

The market cap of Cassava Sciences (SAVA) is approximately 1.3B.

What is Cassava Sciences, Inc.?

Cassava Sciences is a clinical-stage biotechnology company focused on developing treatments and diagnostics for Alzheimer's disease.

What are the main products of Cassava Sciences?

Their main products are simufilam, a treatment for Alzheimer's, and SavaDx, a diagnostic tool for early detection of the disease.

What is simufilam?

Simufilam is an oral therapeutic for Alzheimer's disease, currently in Phase 3 clinical trials to assess its efficacy in improving cognitive function.

What is SavaDx?

SavaDx is an investigational diagnostic product that can detect Alzheimer's disease from a small blood sample, potentially years before symptoms appear.

What recent financial achievements has Cassava Sciences made?

Cassava Sciences recently secured over $125 million from the exercise of warrants, reflecting strong investor confidence.

How can I get more information about Cassava Sciences?

For more information, you can contact Eric Schoen, Chief Financial Officer, at (512) 501-2450 or via email at ESchoen@CassavaSciences.com.

Where can I find the latest updates about Cassava Sciences?

Latest updates can be found in the company's filings with the Securities and Exchange Commission (SEC) and through official press releases.

What is the current status of simufilam's clinical trials?

Simufilam is currently in Phase 3 clinical trials to determine its effectiveness in treating Alzheimer's disease dementia.

What makes SavaDx an innovative diagnostic tool?

SavaDx can potentially detect Alzheimer's disease from a small blood sample years before clinical symptoms appear.

What is Cassava Sciences' mission?

Cassava Sciences aims to address the unmet medical needs of Alzheimer's patients through rigorous scientific research and development.

Cassava Sciences, Inc.

Nasdaq:SAVA

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SAVA Stock Data

1.29B
41.69M
13.38%
29.95%
38.71%
Biotechnology
Pharmaceutical Preparations
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United States of America
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