Rigel Pharmaceuticals Inc Stock Price, News & Analysis

Rigel Pharmaceuticals (Nasdaq: RIGL) has announced the enrollment of the first patient in a Phase 1b/2 triplet therapy trial combining REZLIDHIA® (olutasidenib) with decitabine and venetoclax for mutated isocitrate dehydrogenase-1 (mIDH1) acute myeloid leukemia (AML). This trial, conducted in partnership with MD Anderson Cancer Center, marks the beginning of Rigel's strategic development alliance. The study aims to evaluate the safety, tolerability, and efficacy of this combination in both newly diagnosed and relapsed/refractory mIDH1 AML patients. REZLIDHIA is an oral, small-molecule inhibitor of mIDH1, already approved for relapsed or refractory mIDH1 AML. The trial's primary objective is to determine complete remission rates in 60 patients across two cohorts.

Rigel Pharmaceuticals (Nasdaq: RIGL) has expanded its partnership with Kissei Pharmaceutical to include REZLIDHIA® (olutasidenib) in Japan, South Korea, and Taiwan. The deal grants Kissei exclusive rights to develop and commercialize olutasidenib for all current and potential indications in these territories. Rigel will receive a $10 million upfront payment and is eligible for up to $152.5 million in future milestone payments. Additionally, Rigel will receive product transfer price payments in the mid-twenty to lower-thirty percent range based on tiered net sales for exclusive supply of REZLIDHIA.

REZLIDHIA is currently approved in the U.S. for treating relapsed or refractory mutated IDH1 acute myeloid leukemia (AML). Kissei plans to initially seek approval for REZLIDHIA in Japan for R/R mIDH1 AML. This expansion builds on the existing partnership between Rigel and Kissei for TAVALISSE® (fostamatinib) in the same territories.

Rigel Pharmaceuticals (Nasdaq: RIGL), a biotechnology company focused on hematologic disorders and cancer, announced its participation in two upcoming investor conferences in September 2024. Dean Schorno, the company's CFO, will represent Rigel at:

1. The 2024 Wells Fargo Healthcare Conference in Boston, MA on September 5th for one-on-one meetings.

2. The H.C. Wainwright 26th Annual Global Investment Conference in New York, NY on September 10th, where he will participate in one-on-one meetings and present a company overview at 11:30 a.m. ET.

A live webcast of the H.C. Wainwright presentation will be available on Rigel's website. Founded in 1996, Rigel is based in South San Francisco, California, and is dedicated to developing novel therapies for patients with hematologic disorders and cancer.

Rigel Pharmaceuticals reported Q2 2024 total revenue of $36.8 million, including TAVALISSE net sales of $26.4 million (24% YoY growth), REZLIDHIA net sales of $5.2 million (102% YoY growth), and GAVRETO net sales of $1.9 million. The company successfully completed the NDA transfer of GAVRETO for RET fusion-positive cancers. Rigel reported a net loss of $1.0 million, or $0.06 per share, compared to a $6.6 million loss in Q2 2023. For H1 2024, total revenue was $66.4 million with a net loss of $9.3 million. The company had $49.1 million in cash and equivalents as of June 30, 2024. Rigel continues to advance clinical trials, including a Phase 1b study of R2891 for lower-risk MDS and new combination trials for olutasidenib in AML.

Rigel Pharmaceuticals, Inc. (Nasdaq: RIGL) has announced that it will report its second quarter 2024 financial results after market close on Tuesday, August 6, 2024. The company's senior management will host a live conference call and webcast at 4:30 p.m. Eastern Time (1:30 p.m. Pacific Time) to discuss the financial results and provide a business update. Participants can join the call by dialing 877-407-3088 (domestic) or 201-389-0927 (international). The call and accompanying slides will also be webcast live from the Investor Relations section of Rigel's website at www.rigel.com, where it will be archived for 90 days after the call.

On July 12, 2024, Rigel Pharmaceuticals announced the granting of stock options under its Inducement Plan. This plan, approved by Rigel's Compensation Committee, aligns with NASDAQ Listing Rule 5635(c)(4). The company granted 79,890 stock options to eleven non-executive employees, which will vest over four years with a one-year cliff. This move aims to attract and retain talented employees by providing them with a stake in the company's future.

Rigel is a biotechnology firm focused on developing therapies for hematologic disorders and cancer. Based in South San Francisco, it was established in 1996. The company continues to innovate and provide novel treatments in its industry.

Optime Care has announced an enhanced partnership with Rigel Pharmaceuticals, effective July 1, 2024, to support patients using GAVRETO® (pralsetinib), a targeted cancer therapy. This collaboration leverages Optime Care’s comprehensive services, which include pre-commercialization expertise, market access, national medication fulfillment, and high-touch patient support designed to improve outcomes. The partnership aims to streamline patient access to GAVRETO® through personalized clinical guidance, support with insurance coverage, financial assistance programs, and more. Rigel Pharmaceuticals values Optime Care’s extensive experience in managing complex diseases and their commitment to patient care, aiming to improve therapeutic outcomes for patients with cancers caused by abnormal RET genes.

Rigel Pharmaceuticals announced a 1-for-10 reverse stock split, effective June 27, 2024. This decision will reduce the total outstanding shares from approximately 175.6 million to 17.6 million, aiming to increase the per-share trading price. The reverse split was approved by stockholders on May 24, 2024, and finalized by the Board on June 15, 2024. Post-split, Rigel’s stock will trade under the same symbol (RIGL) and a new CUSIP number (766559702). The reverse split intends to enhance the company’s appeal to institutional investors and maintain Nasdaq listing compliance. No action is required from stockholders who hold shares electronically or in street name; those with physical certificates will receive instructions for the exchange. Fractional shares will be compensated with cash.

Rigel Pharmaceuticals completed the transfer of the New Drug Application (NDA) for GAVRETO® (pralsetinib), an oral targeted therapy for patients with RET fusion-positive non-small cell lung cancer (NSCLC) and advanced thyroid cancer. GAVRETO will be available in the U.S. starting June 27, 2024. The NSCLC indication is fully approved by the FDA, while the advanced thyroid indication is approved under accelerated approval. The drug will be available in 100 mg capsules priced at $11,144.58 for 60 capsules and $16,716.85 for 90 capsules. Rigel offers patient assistance programs and comprehensive support through its RIGEL ONECARE® service. The acquisition of GAVRETO’s U.S. rights from Blueprint Medicines was announced in February 2024.