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Protagenic Therapeutics Inc. (NASDAQ: PTIX) is a biopharmaceutical company based in New York, focusing on the discovery and development of innovative treatments for stress-related neuropsychiatric and mood disorders. Utilizing peptide-based and brain-active therapeutics, the company aims to address critical health challenges such as anxiety, depression, PTSD, and neurodegenerative disorders.
Key to their portfolio is the lead compound, PT00114, a synthetic version of Teneurin Carboxy-terminal Associated Peptide (TCAP), a natural brain signaling peptide known for its potential to modulate stress responses. PT00114 operates with a novel mechanism, reducing cortisol levels and offering promising results in preclinical studies for anxiety, depression, PTSD, and addiction. The company has successfully completed the first dose escalation step in their Phase I clinical trial with PT00114, demonstrating excellent tolerability without adverse safety findings.
In recent developments, Protagenic Therapeutics regained compliance with Nasdaq's listing requirements by maintaining a closing bid price above $1.00 per share for ten consecutive trading days. They have also announced the completion of enrollment in the single dose portion of their Phase 1 trial for PT00114, marking a significant milestone with 30 subjects enrolled across five cohorts.
The company is actively progressing towards transformative therapies, with upcoming plans to discuss their latest financial results and future outlook in an investor earnings call. They are also fostering strategic collaborations, such as partnering with Axiom Real-Time Metrics to manage clinical trials, and participating in prominent industry events like the Peptide Based Therapeutic Summit.
For detailed information about the company's projects and corporate updates, please visit www.protagenic.com.
Protagenic Therapeutics (Nasdaq:PTIX) announced a 1-for-4 reverse stock split effective March 23, 2023, to comply with Nasdaq's minimum bid price requirement. This decision follows shareholder approval on November 23, 2022. The reverse split will convert every four shares into one, reducing the outstanding shares from approximately 17.3 million to about 4.3 million. All stockholders will be uniformly affected, and no fractional shares will be issued. The aim is to increase the stock price above $1.00 for continued listing. Comprehensive details are available on the company’s website and SEC filings.
Protagenic Therapeutics (NASDAQ:PTIX) announced its participation in the B. Riley Securities Neuro and Ophthalmology Virtual Investor Conference set for April 27, 2022, at 10:30 AM ET. The biopharmaceutical company, focused on treating stress-related neurologic disorders, will present on its pre-clinical drug candidates. Investors interested in the conference can access the presentation via this link. For further inquiries or to schedule one-on-one meetings, attendees are encouraged to contact their conference representative.
Protagenic Therapeutics, Inc. (Nasdaq: PTIX) reported its Q3 2021 results, highlighting significant advancements in developing PT00114 for stress-related neurological disorders. The company hosted a virtual science review and KOL webinar, discussing PT00114's potential for treating depression, anxiety, PTSD, and addiction. Financially, net loss decreased to approximately $0.9 million from $1.0 million year-over-year, with R&D expenses also down at $0.3 million. The company holds $10.8 million in cash and plans to refile its IND application in Q4 2021, with a Phase I/IIa study set for Q1 2022.
Protagenic Therapeutics (Nasdaq: PTIX) announces a scientific webinar on September 8, 2021, focused on its neuro-active peptide PT00114, intended for treating Depression, Anxiety, PTSD, and Addiction. The session will feature presentations by key figures including David Lovejoy and Andrew Slee, discussing PT00114's discovery, evidence from disease models, and its role in addiction therapy. The event, lasting from 10:00 AM to 11:00 AM ET, will conclude with a Q&A. Registration is available on Protagenic's website.
Protagenic Therapeutics (PTIX) reported a net loss of approximately $1.5 million for Q2 2021, up from $0.6 million in Q2 2020. Operating and administrative expenses rose significantly, with general and administrative costs reaching about $1.2 million, compared to $0.4 million the prior year. The company closed a $13.2 million public offering and plans to refile its IND application for PT00114 in Q4 2021, with a Phase I/IIa study set to initiate in Q1 2022. As of June 30, 2021, PTIX had $11.9 million in cash and approximately 16.6 million shares outstanding.
Protagenic Therapeutics (Nasdaq: PTIX) announced that the FDA has requested the company to provide clinical sites with ready-to-inject vials instead of drug substances for local formulation. This change allows Protagenic to maintain control over the final drug product formulation. The company plans to comply with this directive and refile its Investigational New Drug (IND) application to initiate patient enrollment in Q4 2021. The company focuses on developing therapies for stress-related neurologic disorders.
Protagenic Therapeutics (Nasdaq: PTIX) will host a webinar on July 13, 2021, at 10:00 AM ET, to discuss PT00114, a potential treatment for stress-related disorders such as Depression, PTSD, Anxiety, and Addiction. The webinar features Dr. Maurizio Fava, a leading psychiatrist and principal investigator for the upcoming Phase 1/2a trial. He will provide insights into the clinical development of PT00114, a peptide aimed at regulating stress response in the brain. Interested participants can contact James Carbonara at Hayden IR for registration details.
Protagenic Therapeutics, Inc. (NASDAQ: PTIX) is set to present at the H.C. Wainwright Psychedelics in Psychiatry and Beyond Virtual Conference on June 17, 2021, at 8:30 AM ET. The company focuses on developing drug candidates aimed at treating stress-related neurologic disorders. Interested parties can access the presentation through the provided link. For further inquiries or to schedule one-on-one meetings, contact conference representatives or management.
Protagenic is exploring first-in-class neuro-active peptides for therapeutic applications.
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