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Personalis and Tempus Announce Expanded Collaboration

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Personalis (PSNL) and Tempus (TEM) have expanded their commercial collaboration, with Tempus investing $36 million in Personalis. This investment includes exercising warrants to purchase 9.2 million shares at an average price of $2.00 and buying an additional 3.5 million shares at $5.07 each. The expansion follows strong demand for their ultra-sensitive MRD testing in breast and lung cancers, as well as immunotherapy monitoring across solid tumors.

Key points of the expanded collaboration include:

  • Tempus accelerating commercialization efforts over the first two years
  • Personalis increasing the quantity of patient samples it will accept
  • Tempus becoming the exclusive commercial partner for Personalis' MRD product
  • Tempus owning approximately 19.3% of Personalis' outstanding common stock after the transaction

Personalis (PSNL) e Tempus (TEM) hanno ampliato la loro collaborazione commerciale, con Tempus che investe 36 milioni di dollari in Personalis. Questo investimento include l'esercizio di warrant per l'acquisto di 9,2 milioni di azioni a un prezzo medio di 2,00 dollari e l'acquisto di ulteriori 3,5 milioni di azioni a 5,07 dollari ciascuna. L'espansione segue una forte domanda per i loro test MRD ultra-sensibili nei tumori al seno e ai polmoni, così come per il monitoraggio dell'immunoterapia nei tumori solidi.

Punti chiave della collaborazione ampliata includono:

  • Tempus che accelera gli sforzi di commercializzazione nei primi due anni
  • Personalis che aumenta la quantità di campioni di pazienti che accetterà
  • Tempus diventa il partner commerciale esclusivo per il prodotto MRD di Personalis
  • Tempus possiede circa il 19,3% delle azioni ordinarie in circolazione di Personalis dopo la transazione

Personalis (PSNL) y Tempus (TEM) han ampliado su colaboración comercial, con Tempus invirtiendo 36 millones de dólares en Personalis. Esta inversión incluye el ejercicio de warrants para comprar 9,2 millones de acciones a un precio promedio de 2,00 dólares y la compra de 3,5 millones de acciones adicionales a 5,07 dólares cada una. La expansión sigue una fuerte demanda por sus pruebas MRD ultra-sensibles en cánceres de mama y pulmón, así como en el monitoreo de inmunoterapia en tumores sólidos.

Puntos clave de la colaboración ampliada incluyen:

  • Tempus acelerando los esfuerzos de comercialización en los primeros dos años
  • Personalis aumentando la cantidad de muestras de pacientes que aceptará
  • Tempus convirtiéndose en el socio comercial exclusivo para el producto MRD de Personalis
  • Tempus poseyendo aproximadamente el 19,3% de las acciones ordinarias en circulación de Personalis después de la transacción

Personalis (PSNL)와 Tempus (TEM)는 상업적 협력을 확장하여 Tempus가 Personalis에 3천6백만 달러를 투자했습니다. 이 투자는 평균 가격 2.00달러에 920만 주를 구매할 수 있는 워런트를 행사하고, 추가로 3.5백만 주를 각각 5.07달러에 구매하는 것을 포함합니다. 이 확장은 유방암 및 폐암에서 그들의 초감도 MRD 테스트에 대한 강한 수요와 고형 종양 전반의 면역요법 모니터링 요청에 뒤따릅니다.

확대된 협력의 주요 사항은 다음과 같습니다:

  • Tempus가 처음 두 해 동안 상업화 노력을 가속화합니다
  • Personalis가 수용할 환자 샘플 수를 증가시킵니다
  • Tempus가 Personalis의 MRD 제품에 대한 독점 상업 파트너가 됩니다
  • Tempus는 거래 이후 Personalis의 유통되는 보통주 약 19.3%를 소유합니다

Personalis (PSNL) et Tempus (TEM) ont élargi leur collaboration commerciale, avec Tempus investissant 36 millions de dollars dans Personalis. Cet investissement inclut l'exercice de bons de souscription pour acheter 9,2 millions d'actions à un prix moyen de 2,00 dollars et l'achat de 3,5 millions d'actions supplémentaires à 5,07 dollars chacune. L'expansion suit une forte demande pour leurs tests MRD ultra-sensibles dans les cancers du sein et du poumon, ainsi que pour le suivi de l'immunothérapie dans les tumeurs solides.

Les points clés de la collaboration élargie incluent :

  • Tempus accélérant les efforts de commercialisation au cours des deux premières années
  • Personalis augmentant le nombre d'échantillons de patients qu'elle acceptera
  • Tempus devenant le partenaire commercial exclusif pour le produit MRD de Personalis
  • Tempus détenant environ 19,3 % des actions ordinaires en circulation de Personalis après la transaction

Personalis (PSNL) und Tempus (TEM) haben ihre kommerzielle Zusammenarbeit erweitert, wobei Tempus 36 Millionen Dollar in Personalis investiert. Diese Investition umfasst die Ausübung von Warrants zum Kauf von 9,2 Millionen Aktien zu einem durchschnittlichen Preis von 2,00 Dollar sowie den Kauf von weiteren 3,5 Millionen Aktien zu je 5,07 Dollar. Die Expansion folgt einer starken Nachfrage nach ihren ultrasensitiven MRD-Tests bei Brust- und Lungenkrebs sowie bei der Überwachung der Immuntherapie bei soliden Tumoren.

Wichtige Punkte der erweiterten Zusammenarbeit sind:

  • Tempus beschleunigt die Vermarktungsanstrengungen in den ersten zwei Jahren
  • Personalis erhöht die Anzahl der Patient*innenproben, die sie akzeptieren wird
  • Tempus wird der exklusive Vertriebspartner für das MRD-Produkt von Personalis
  • Tempus besitzt nach der Transaktion etwa 19,3% der ausstehenden Aktien von Personalis
Positive
  • Tempus investing $36 million in Personalis, strengthening their financial position
  • Expanded collaboration due to strong demand for their MRD testing product
  • Accelerated commercialization efforts by Tempus over the next two years
  • Increased capacity for patient sample processing by Personalis
  • Exclusive commercial partnership for Personalis' MRD product in key cancer areas
Negative
  • Potential dilution of existing shareholders due to the issuance of new shares to Tempus

The expanded collaboration between Personalis and Tempus marks a significant financial development. Tempus' $36 million investment through warrant exercises and share purchases is a strong vote of confidence in Personalis' technology and market potential. This infusion of capital could substantially improve Personalis' financial position and fuel its growth initiatives.

The deal structure, combining warrant exercises at $2.00 and new share purchases at $5.07, suggests a positive valuation trajectory for Personalis. Post-transaction, Tempus will own 19.3% of Personalis, indicating a deepening strategic alignment between the companies. This could lead to enhanced synergies and potentially more favorable terms for Personalis in future collaborations.

The accelerated collaboration between Personalis and Tempus in the field of ultra-sensitive MRD (Minimal Residual Disease) testing represents a significant advancement in cancer diagnostics. Their focus on breast and lung cancers, along with immunotherapy monitoring across solid tumors, addresses critical areas of oncology with high clinical demand.

The reported strong demand following their ASCO meeting presentation indicates a positive reception from the medical community. This expanded partnership could lead to faster market penetration and potentially earlier detection of cancer recurrence, improving patient outcomes. The increased capacity for patient sample processing suggests confidence in scaling up operations, which could accelerate clinical adoption and data collection for further research.

The expanded collaboration between Personalis and Tempus signals a growing market opportunity in precision oncology. The accelerated commercialization efforts and increased sample processing capacity indicate strong market demand for ultra-sensitive MRD testing, particularly in breast and lung cancers.

Tempus' exclusive commercial partnership for Personalis' MRD product could lead to rapid market penetration, leveraging Tempus' existing networks and resources. The positive reaction from the ASCO meeting suggests high interest from healthcare providers, potentially leading to faster adoption rates. This collaboration could significantly reshape the competitive landscape in the cancer diagnostics market, potentially challenging established players and accelerating the shift towards personalized medicine in oncology.

Tempus invests $36 million by exercising warrants and purchasing additional shares

FREMONT, Calif.--(BUSINESS WIRE)-- Personalis, Inc. (Nasdaq: PSNL) and Tempus AI, Inc. (Nasdaq: TEM) announced today that the companies have expanded their commercial relationship. The companies agreed in November 2023 to collaborate and bring ultra-sensitive MRD testing to market and launched their efforts at the recent ASCO meeting. Tempus is serving as exclusive commercial partner for Personalis’ ultra-sensitive tumor-informed MRD product for broad patient adoption in breast and lung cancers, and for immunotherapy monitoring across all solid tumors.

Following positive reaction and exceptionally strong demand, the companies have agreed to accelerate their efforts, expanding under the following key terms:

  • Tempus to accelerate its commercialization efforts over the first two years
  • Personalis to increase the quantity of patient samples it will accept over the corresponding period
  • Tempus to invest approximately $36 million into Personalis

“We are pleased that our early access program is proceeding well and demand is strong,” said Chris Hall, CEO of Personalis. “We believe the expansion of the relationship with Tempus will allow us to better capitalize on the opportunity.”

Under the agreement, Tempus agreed to exercise its existing warrants to purchase 9.2 million shares of common stock in accordance with their terms at an average purchase price of $2.00 and to purchase an additional 3.5 million shares of common stock at a price per share of $5.07, which was the last reported closing price of Personalis’ common stock as reported on The Nasdaq Global Market on August 15, 2024, for a total investment of approximately $36 million in Personalis. As a result, Tempus will own approximately 19.3 percent of Personalis’ outstanding common stock following the closing of the transactions.

About Personalis, Inc.

At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient. Our highly sensitive assays combine tumor-and-normal profiling with proprietary algorithms to deliver advanced insights even as cancer evolves over time. Our products are designed to detect minimal residual disease (MRD) and recurrence at the earliest time points, enable the selection of targeted therapies based on ultra-comprehensive genomic profiling, and enhance biomarker strategy for drug development. Personalis is based in Fremont, California. To learn more, visit www.personalis.com and connect with us on LinkedIn and X (Twitter).

Forward-Looking Statements

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements in this press release that are not historical are “forward-looking statements” within the meaning of U.S. securities laws, including statements relating to the advantages of an expanded relationship with Tempus. Such forward-looking statements involve known and unknown risks and uncertainties and other factors that may cause actual results to differ materially from any anticipated results or expectations expressed or implied by such statements, including the risks, uncertainties and other factors that relate to Personalis’ achievement of milestones set forth in the collaboration and co-commercialization agreement with Tempus, including processing of the increased quantity of patient samples, and the success of Tempus’ sales and marketing efforts, including acceleration of Tempus’ commercialization efforts. These and other potential risks and uncertainties that could cause actual results to differ materially from the results predicted in these forward-looking statements are described under the captions “Risk Factors” and “Management’s Discussion and Analysis of Financial Condition and Results of Operations” in Personalis’ Annual Report on Form 10-K for the year ended December 31, 2023, filed with the Securities and Exchange Commission (SEC) on February 28, 2024, and its Quarterly Report on Form 10-Q for the quarter ended June 30, 2024, filed with the SEC on August 7, 2024. All information provided in this release is as of the date of this press release, and any forward-looking statements contained herein are based on assumptions that we believe to be reasonable as of this date. Undue reliance should not be placed on the forward-looking statements in this press release, which are based on information available to us on the date hereof. Personalis undertakes no duty to update this information unless required by law.

Investors:

Caroline Corner

investors@personalis.com

415-202-5678

Media:

pr@personalis.com

Source: Personalis, Inc.

FAQ

What is the value of Tempus' investment in Personalis (PSNL)?

Tempus is investing approximately $36 million in Personalis (PSNL) by exercising warrants and purchasing additional shares.

How many shares of Personalis (PSNL) will Tempus own after the investment?

Following the investment, Tempus will own approximately 19.3% of Personalis' (PSNL) outstanding common stock.

What is the focus of the collaboration between Personalis (PSNL) and Tempus?

The collaboration focuses on bringing ultra-sensitive MRD testing to market for breast and lung cancers, as well as immunotherapy monitoring across all solid tumors.

What are the key terms of the expanded collaboration between Personalis (PSNL) and Tempus?

Key terms include Tempus accelerating commercialization efforts, Personalis increasing patient sample processing capacity, and Tempus becoming the exclusive commercial partner for Personalis' MRD product.

Personalis, Inc.

NASDAQ:PSNL

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Diagnostics & Research
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FREMONT