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Prelude Therapeutics Incorporated - PRLD STOCK NEWS

Welcome to our dedicated page for Prelude Therapeutics Incorporated news (Ticker: PRLD), a resource for investors and traders seeking the latest updates and insights on Prelude Therapeutics Incorporated stock.

Prelude Therapeutics Incorporated (Nasdaq: PRLD) is a clinical-stage biopharmaceutical company focused on developing innovative small molecule therapies targeting key mechanisms in cancers with high unmet needs. Founded in 2016 and headquartered in Wilmington, Delaware, the company's mission is to deliver precision oncology treatments that can address the critical pathways in cancer cells.

Prelude's robust pipeline includes several promising drug candidates currently in clinical development:

  • PRT543: This candidate is in Phase 1 clinical trials targeting select solid tumors and myeloid malignancies in patients who are refractory to or intolerant of established therapies.
  • PRT811: Also in Phase 1 trials, PRT811 focuses on solid tumors, including glioblastoma multiforme and primary central nervous system lymphomas.
  • PRT1419: A potent and selective inhibitor of the anti-apoptotic protein MCL1, which is undergoing clinical evaluation for its efficacy and safety in cancer treatment.
  • PRT2527: This highly selective CDK9 inhibitor demonstrates substantial potential in treating solid and hematological malignancies and aims to minimize off-target toxicities.
  • PRT3645: A next-generation CDK4/6 inhibitor that shows promise for better safety, tolerability, and efficacy in various cancers beyond breast cancer.
  • PRT3789: A first-in-class SMARCA2 protein degrader targeting cancers with SMARCA4 mutations.

In recent developments, Prelude has extended its cash runway into 2026 following a successful public offering, raising approximately $113 million in gross proceeds. Their strategic collaboration with AbCellera aims to co-develop innovative antibody drug conjugate therapies, combining AbCellera's antibody discovery platform with Prelude's expertise in medicinal chemistry and drug development.

Prelude's financial strength is evident with cash, cash equivalents, and marketable securities totaling $255 million as of June 30, 2023. Their focused approach on advancing their pipeline and making critical strategic decisions is supported by clinical data showing promising efficacy and safety profiles for their drug candidates, such as PRT2527 and PRT1419. The company's commitment to addressing cancers with high unmet needs positions it as a significant player in precision oncology.

For more detailed information and the latest updates on Prelude Therapeutics' research advancements, financial performance, and strategic initiatives, visit their official website and follow them on LinkedIn and Twitter.

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Prelude Therapeutics Incorporated (Nasdaq: PRLD) will participate in the Citizens JMP Life Sciences Conference in New York City on May 13 and 14. The Company's CEO and Chief Medical Officer will engage in a fireside chat, with a live webcast accessible on their website. The event aims to showcase the company's developments in precision oncology.

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Prelude Therapeutics Incorporated (Nasdaq: PRLD) reported its financial results for the first quarter of 2024, highlighting progress in clinical development of lead drug candidates, PRT3789 and PRT2527. Operational leadership was strengthened by new hires. The company's cash runway extends into 2026 with $201.9 million in cash, cash equivalents, and marketable securities as of March 31, 2024.

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Prelude Therapeutics (Nasdaq: PRLD) presents new preclinical data at AACR Annual Meeting showcasing promising results for its SMARCA2 degrader, CDK9 inhibitor, and CDK4/6 inhibitor. The SMARCA2 degrader, PRT7732, exhibits high potency and selectivity, with plans for Phase 1 trials in 2024. The CDK9 inhibitor, PRT2527, shows efficacy in hematological models and is in Phase 1 trials. The CDK4/6 inhibitor, PRT3645, displays synergies in breast cancer, CRC, and NSCLC models, hinting at improved patient outcomes.
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Prelude Therapeutics Incorporated announces the acceptance of three posters with preclinical data on its highly selective oral SMARCA2 degrader, potentially best-in-class CDK9 inhibitor, and next-generation CDK4/6 inhibitor for presentation at the AACR Annual Meeting 2024. The Company's Chief Scientific Officer, Peggy Scherle, looks forward to sharing data on the preclinical characterization of PRT7732, the lead oral SMARCA2 degrader, which is set to enter Phase 1 clinical development in the second half of the year. Additionally, preclinical data for the highly selective CDK9 inhibitor, PRT2527, and the next-generation CDK4/6 inhibitor, PRT3645, will be presented, highlighting their potential therapeutic value in various cancer types. The Company will also host a live webcast to discuss the role of SMARCA in cancer and its clinical relevance.
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Prelude Therapeutics Incorporated (Nasdaq: PRLD) will participate in the Barclays Global Healthcare Conference. The CEO and Chief Medical Officer will be part of a fireside chat on March 13, 2024. The event will be live webcasted and archived on the company's website.
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Prelude Therapeutics Incorporated (PRLD) reports financial results for 2023 and outlines key objectives for 2024. The company focuses on first-in-class IV SMARCA2 degrader and potentially best-in-class CDK9 inhibitor. A partnership with AbCellera aims to develop precision ADCs. The company has a cash runway into 2026 with $232.9 million in cash. Clinical milestones for 2024 include proof-of-concept data for SMARCA2 degrader and CDK9 inhibitor.
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Prelude Therapeutics Incorporated (Nasdaq: PRLD) announced a private placement to raise approximately $25 million in gross proceeds, which will be used to fund the advancement of its SMARCA2 portfolio, for working capital, and general corporate purposes. The additional funding is expected to sustain the company's operations until 2026.
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Prelude Therapeutics announces the prioritization of its SMARCA2 degrader and CDK9 inhibitor programs for continued clinical development. The company also enters a partnership with AbCellera to develop precision ADCs. Prelude has a cash runway into 2026 with $230.5 million in cash, cash equivalents, and marketable securities.
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Prelude Therapeutics and AbCellera have announced a multi-year, multi-program partnership to discover, develop, and commercialize novel oncology medicines. The collaboration will focus on up to five programs, with the first program targeting a SMARCA degrader. Prelude will lead clinical development and global commercialization, while AbCellera will lead manufacturing activities.
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Prelude Therapeutics to participate in three upcoming healthcare investment conferences
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FAQ

What is the current stock price of Prelude Therapeutics Incorporated (PRLD)?

The current stock price of Prelude Therapeutics Incorporated (PRLD) is $1.3 as of December 20, 2024.

What is the market cap of Prelude Therapeutics Incorporated (PRLD)?

The market cap of Prelude Therapeutics Incorporated (PRLD) is approximately 48.9M.

What does Prelude Therapeutics Incorporated specialize in?

Prelude Therapeutics specializes in the discovery and development of small molecule therapies targeting key mechanisms in cancers with high unmet needs.

Where is Prelude Therapeutics Incorporated based?

Prelude Therapeutics is based in Wilmington, Delaware.

What are some key drug candidates in Prelude Therapeutics' pipeline?

Some key drug candidates include PRT543, PRT811, PRT1419, PRT2527, PRT3645, and PRT3789.

What is PRT2527?

PRT2527 is a highly selective CDK9 inhibitor demonstrating potential in treating solid and hematological malignancies while minimizing off-target toxicities.

What recent financial achievement has Prelude Therapeutics reported?

Prelude Therapeutics recently raised approximately $113 million in gross proceeds from a public offering, extending their cash runway into 2026.

Who has Prelude Therapeutics partnered with for drug development?

Prelude Therapeutics has partnered with AbCellera to co-develop innovative antibody drug conjugates.

What is PRT3645?

PRT3645 is a next-generation CDK4/6 inhibitor focusing on improved safety, tolerability, and efficacy in various cancers beyond breast cancer.

What is the focus of PRT3789?

PRT3789 is a first-in-class SMARCA2 degrader targeting cancers with SMARCA4 mutations.

What are the financial resources available to Prelude Therapeutics?

As of June 30, 2023, Prelude Therapeutics had cash, cash equivalents, and marketable securities totaling $255 million.

Where can I find more information about Prelude Therapeutics?

For more information, visit Prelude Therapeutics' official website at www.preludetx.com and follow them on LinkedIn and Twitter.

Prelude Therapeutics Incorporated

Nasdaq:PRLD

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PRLD Stock Data

48.87M
27.45M
9.06%
85.82%
5.26%
Biotechnology
Pharmaceutical Preparations
Link
United States of America
WILMINGTON