PainReform Ltd. Ordinary Shares - PRFX STOCK NEWS

PainReform Ltd. (Nasdaq: PRFX), a clinical stage specialty pharmaceutical company, announced participation in the H.C. Wainwright BioConnect 2021 Conference, occurring virtually from January 11-14, 2021. A webcast of the presentation will be available on-demand starting January 11, 2021, at 6:00 a.m. ET, accessible for 90 days. PainReform's lead product, PRF-110, aims to enhance post-operative pain relief using a proprietary extended-release drug-delivery system, targeting the local anesthetic market with reduced opiate needs.

PainReform Ltd. (Nasdaq: PRFX) has appointed Rita Keynan as Vice President of Pharmaceutical Operations. With over 25 years in the pharmaceutical sector, Keynan has a solid background in drug development, overseeing all facets from early trials to NDA filings. Her prior role was with VYNE Therapeutics, managing a team focused on drug development. CEO Ilan Hadar expressed confidence in her capabilities as the company prepares for Phase 3 trials of their lead product, PRF-110, aimed at post-operative pain relief through an innovative drug-delivery system.

PainReform Ltd. (NasdaqCM:PRFX) announced the appointment of Lotus Clinical Research as its CRO for the upcoming Phase 3 trial of PRF-110. This trial will focus on patients undergoing bunionectomy and hernia repair operations. LCR is specialized in analgesic studies, with a history of approximately 350 trials resulting in over ten approvals. Previous Phase 2 results showed PRF-110 provided pain relief for up to 72 hours, outperforming ropivacaine's 2-6 hours. The CEO stated confidence in the trial's design, aiming to address the opioid crisis while demonstrating safer pain relief options.

PainReform Ltd. (NASDAQ:PRFX) has appointed Ilan Hadar as its new CEO, effective immediately. With over 20 years in the pharmaceutical sector, Hadar has led operations and developed products in the U.S. and Israel. His previous roles include serving as Country Manager and CFO at Foamix Pharmaceuticals and Finance Director at Pfizer. The appointment comes as PainReform prepares for pivotal Phase 3 trials for its lead product PRF-110, aimed at changing post-operative pain management by reducing reliance on opioids.

PainReform Ltd. (NASDAQ:PRFX) has appointed Dr. Ellen Baron to its Board of Directors, enhancing its leadership after a recent IPO. Dr. Baron brings over 20 years of experience in the healthcare and capital markets sectors, previously holding key positions at Outcome Capital LLC and Healthios Capital Markets. Her expertise in business development and clinical affairs will be pivotal as PainReform advances its PRF-110 drug through Phase 3 trials aimed at the post-operative pain relief market. The company is optimistic about its future growth potential, targeting a significant market opportunity.

PainReform Ltd. (NASDAQ:PRFX) has appointed Augustine Lawlor to its Board of Directors following its recent IPO. Lawlor, with extensive experience in the pharmaceutical sector, previously served as COO of Leap Therapeutics and held key positions at LeukoSite and Alpha-Beta Technologies. His expertise includes finance, business development, and mergers and acquisitions, making him a valuable addition as PainReform advances its lead product, PRF-110, through Phase 3 trials. This product aims to revolutionize post-operative pain management while potentially reducing reliance on opioids.

PainReform Ltd. (NASDAQCM:PRFX) provided updates on its lead drug candidate PRF-110, demonstrating unique surgical benefits beyond pain relief. Studies showed PRF-110 does not affect suture integrity or wound healing, targeting the post-operative pain market. The drug offers up to 72 hours of pain reduction with no serious adverse events reported. As PainReform advances into Phase 3 studies for bunionectomy and hernia repair, the company believes PRF-110 could significantly alter post-surgical practices and address the opioid crisis, potentially capturing a share in the $12 billion market.

PainReform Ltd. (NASDAQ:PRFX) has initiated preparations for pivotal Phase 3 clinical trials of PRF-110, aimed at treating post-operative pain, following a successful initial public offering that raised $20 million. The FDA has granted an IND for PRF-110, supported by positive Phase 2 results. The trials are designed to be brief, with primary endpoints based on a standard pain scale. PRF-110, a clear, viscous solution containing the well-known anesthetic ropivacaine, is intended to provide localized and extended pain relief, potentially reducing opiate use. The post-operative pain market is projected to grow from $12 billion to over $45 billion by 2026.

PainReform Ltd. (NASDAQ:PRFX) closed its initial public offering on September 3, 2020, offering 2,500,000 units at $8.00 each, yielding approximately $20 million before expenses. Each unit comprises one Ordinary Share and one Warrant for an additional share, separable upon issuance. The Ordinary Shares began trading on Nasdaq on September 1, 2020. Underwriters have a 45-day option to purchase up to 375,000 additional shares or warrants to cover over-allotments. PainReform focuses on reformulating established therapeutics, with its lead product PRF-110 targeting post-operative pain relief.