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Poolbeg Pharma PLC Announces Significant POLB 001 Patent Granted in USA

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Poolbeg Pharma PLC has announced the significant granting of the POLB 001 patent in the USA, reinforcing its intellectual property portfolio. The patent covers drugs for treating hypercytokinaemia and preventing cytokine storms in patients post-immune response. This strengthens the company's IP portfolio and enhances the value of POLB 001 for potential partners. Poolbeg Pharma is actively building a global IP portfolio, with additional patents for severe influenza and cytokine release syndrome after cancer immunotherapy.

Poolbeg Pharma PLC ha annunciato l'importante concessione del brevetto POLB 001 negli USA, che rafforza il suo portafoglio di proprietà intellettuale. Il brevetto riguarda farmaci per il trattamento dell'ipercitochinemia e la prevenzione delle tempeste di citochine nei pazienti dopo la risposta immunitaria. Questo potenzia il portafoglio IP dell'azienda e aumenta il valore del POLB 001 per i potenziali partner. Poolbeg Pharma è attivamente impegnata nella costruzione di un portafoglio IP globale, con ulteriori brevetti per l'influenza grave e la sindrome di rilascio di citochine dopo l'immunoterapia contro il cancro.
Poolbeg Pharma PLC ha anunciado la significativa concesión de la patente POLB 001 en EE. UU., lo que refuerza su cartera de propiedad intelectual. La patente abarca medicamentos para tratar la hipercitokinemia y prevenir tormentas de citocinas en pacientes tras una respuesta inmunitaria. Esto fortalece la cartera de PI de la compañía y aumenta el valor de POLB 001 para socios potenciales. Poolbeg Pharma está construyendo activamente una cartera de PI global, con patentes adicionales para la influenza severa y el síndrome de liberación de citocinas después de la inmunoterapia contra el cáncer.
풀베그 파르마 PLC는 미국에서 POLB 001 특허의 중요한 부여를 발표했습니다. 이는 회사의 지적 재산 포트폴리오를 강화합니다. 해당 특허는 면역 반응 후 환자에서 과도한 사이토카인 생성을 치료하고 사이토카인 폭풍을 예방하는 약물을 다룹니다. 이는 회사의 IP 포트폴리오를 강화하고 POT 001의 잠재적 파트너들에 대한 가치를 높입니다. 풀베그 파르마는 심각한 인플루엔자 및 암 면역 치료 후 사이토카인 방출 증후군에 대한 추가 특허를 포함하여 글로벌 IP 포트폴리오를 적극적으로 구축하고 있습니다.
Poolbeg Pharma PLC a annoncé l'octroi significatif du brevet POLB 001 aux États-Unis, renforçant ainsi son portefeuille de propriété intellectuelle. Le brevet couvre les médicaments pour traiter l'hypercytokinémie et prévenir les tempêtes de cytokines chez les patients après une réponse immunitaire. Cela renforce le portefeuille de PI de l'entreprise et augmente la valeur de POLB 001 pour les partenaires potentiels. Poolbeg Pharma construit activement un portefeuille mondial de PI, avec des brevets supplémentaires pour la grippe sévère et le syndrome de libération de cytokines après une immunothérapie contre le cancer.
Poolbeg Pharma PLC hat die bedeutsame Erteilung des POLB 001 Patents in den USA bekanntgegeben, was das Portfolio an geistigem Eigentum stärkt. Das Patent umfasst Medikamente zur Behandlung von Hyperzytokinämie und zur Verhinderung von Zytokinstürmen bei Patienten nach einer Immunantwort. Dies stärkt das IP-Portfolio des Unternehmens und erhöht den Wert von POLB 001 für potenzielle Partner. Poolbeg Pharma baut aktiv ein globales IP-Portfolio auf, mit weiteren Patenten für schwere Influenza und Zytokinfreisetzungs-Syndrom nach Krebsimmuntherapie.
Positive
  • The fully granted POLB 001 patent in the USA strengthens Poolbeg Pharma's intellectual property portfolio.

  • Enhances the value and attractiveness of POLB 001 for potential partners.

  • Poolbeg Pharma is actively expanding its patent portfolio with additional patents for severe influenza and cytokine release syndrome after cancer immunotherapy.

  • POLB 001 shows promise in addressing unmet medical needs in cancer immunotherapy-induced CRS and severe influenza.

  • Positive impact on patients and healthcare systems with a promising market opportunity of over US$10 billion in cancer immunotherapy-induced CRS alone.

  • Strong confidence in POLB 001's potential to positively impact global health and generate value for shareholders.

Negative
  • None.

Significant POLB 001 Patent Granted in United States

Immunomodulator II patent grant further strengthens robust intellectual property portfolio for partnering

LONDON, UK / ACCESSWIRE / May 1, 2024 / Poolbeg Pharma (AIM:POLB)(OTCQB:POLBF, 'Poolbeg' or the 'Company'), a biopharmaceutical company focussed on the development and commercialisation of innovative medicines targeting diseases with a high unmet medical need, announces that, further to its announcement on20 March 2024,the Company has received the fully granted patent from the US Patent Office for its Immunomodulator II patent application.

The claims cover a class of drugs (including POLB 001) for treating hypercytokinaemia (cytokine storm) and for preventing hypercytokinaemia in a patient after an immune response has been triggered. This encompasses cytokine storm that is induced in any disease indication. This further strengthens the Company's robust intellectual property portfolio for POLB 001, thereby enhancing the value and attractiveness of POLB 001 to potential Pharma partners.

Poolbeg is actively building a comprehensive and worldwide IP portfolio, with patents in place covering p38 MAP kinase inhibitors for the treatment of severe influenza; and covering POLB 001 for the treatment of hypercytokinaemia. Further patent applications have been filed and have complementary coverage as the Company continues to expand its patent portfolio covering POLB 001 and the wider class of p38 MAP kinase inhibitors, particularly in respect of the treatment of cytokine release syndrome following cancer immunotherapy.

Jeremy Skillington, PhD, Chief Executive Officer of Poolbeg Pharma, commented:"The grant received from the US Patent Office highlights the strong progress we continue to make in developing and strengthening our patent portfolio for POLB 001, across multiple disease indications. This further enhances the value and attractiveness of POLB 001 for potential partners.

"We believe POLB 001 holds immense promise in addressing unmet medical needs in cancer immunotherapy-induced cytokine release syndrome (CRS) and severe influenza, positively impacting patients and healthcare systems alike. Its impressive data package and strong patent portfolio, coupled with the promising >US$10 billion market opportunity in cancer immunotherapy-induced CRS alone, strengthens our confidence in its potential to positively impact global health and generate value for our shareholders."

Enquiries

Poolbeg Pharma Plc

Jeremy Skillington, CEO

Ian O'Connell, CFO

+44 (0) 207 183 1499

Cavendish Capital Markets Ltd (Nominated Adviser & Joint Broker)

Geoff Nash, Charlie Beeson, Nigel Birks, Harriet Ward (ECM)

+44 (0) 207 220 0500

Shore Capital Stockbrokers Ltd (Joint Broker)

David Coaten, Harry Davies-Ball (Corporate Advisory), Malachy McEntyre, Isobel Jones (Corporate Broking)

+44 (0) 207 408 4090

J&E Davy (Joint Broker)

Anthony Farrell, Niall Gilchrist

+353 (0) 1 679 6363

Optimum Strategic Communications

Nick Bastin, Vici Rabbetts, Elena Bates

+44 (0) 208 078 4357

poolbeg@optimumcomms.com

About Poolbeg Pharma

Poolbeg Pharma plc is committed to the development and commercialisation of innovative medicines targeting diseases with a high unmet medical need, with a growing emphasis on rare and orphan diseases. Its model focusses upon developing its exciting clinical assets and commercialising approved and marketed drugs to support the growth of the Company and the development of its robust pipeline of innovative products, thereby driving significant value creation.

Poolbeg is led by an experienced leadership team with a history of delivering significant shareholder value. The team has been strengthened by the appointment of three former members of the Amryt Pharma plc leadership team, with the intention of repeating Amryt's success and generating near term revenues.

Poolbeg's clinical programmes target large addressable markets including cancer immunotherapy-induced CRS, infectious disease, and metabolic conditions such as obesity with the development of an oral GLP-1R agonist. It uses a cost-effective development philosophy to generate high quality human data to support partnering and further development. Its AI-led infectious disease programmes analyse unique data from human challenge trials to identify clinically relevant drug targets and treatments, leading to faster development and greater commercial appeal.

For more information, please go to www.poolbegpharma.com or follow us on Twitter and LinkedIn @PoolbegPharma.

Forward-Looking Statements

This announcement may contain forward-looking statements and the words "expect", "anticipate", "intends", "plan", "estimate", "aim", "forecast", "project" and similar expressions (or their negative) identify certain of these forward-looking statements. The forward-looking statements in this announcement are based on numerous assumptions and Poolbeg's present and future business strategies and the environment in which Poolbeg expects to operate in the future. Forward-looking statements involve inherent known and unknown risks, uncertainties and contingencies because they relate to events and depend on circumstances that may or may not occur in the future and may cause the actual results, performance or achievements to be materially different from those expressed or implied by such forward-looking statements. These statements are not guarantees of future performance or the ability to identify and consummate investments. Many of these risks and uncertainties relate to factors that are beyond Poolbeg's ability to control or estimate precisely, such as future market conditions, currency fluctuations, the behaviour of other market participants, the outcome of clinical trials, the actions of regulators and other factors such as Poolbeg's ability to obtain financing, changes in the political, social and regulatory framework in which Poolbeg operates or in economic, technological or consumer trends or conditions. Past performance should not be taken as an indication or guarantee of future results, and no representation or warranty, express or implied, is made regarding future performance. No person is under any obligation to update or keep current the information contained in this announcement or to provide the recipient of it with access to any additional relevant information.

This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact rns@lseg.com or visit www.rns.com.

SOURCE: Poolbeg Pharma PLC



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Medicinal and Botanical Manufacturing
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