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Peak Bio, Inc. (PKBO) is a clinical-stage biopharmaceutical company dedicated to pioneering the next generation of therapeutics for oncology and inflammatory orphan/rare diseases. With headquarters in Pleasanton, CA, Peak Bio's innovative approach centers around the development of antibody-drug conjugates (ADCs), which combine novel toxins with antibodies to selectively target and eradicate cancer cells.
Oncology Platform: At the core of Peak Bio's oncology platform is the PH-1 toxin, a dual-action payload that not only targets cancer cells directly but also engages the immune system to enhance cancer cell destruction. This dual mechanism aims to leave behind immune memory cells, potentially providing lasting immunity against cancer relapse. The company's lead ADC candidate, Trop2 PH1, has demonstrated significant preclinical efficacy and safety, promising a new frontier in cancer treatment.
Pipeline and Partnerships: Peak Bio's lead product candidate, PHP-303, is a fifth-generation small molecule neutrophil elastase inhibitor. This promising drug is set to enter Phase II clinical trials for Alpha1 anti-trypsin deficiency disorder (AATD). Peak Bio has successfully completed Phase I studies, showing a favorable safety profile. The company has also announced collaborations and partnerships aimed at advancing its ADC and inflammatory disease programs, including an amended stock purchase agreement with White Lion Capital, providing up to $100 million in funding to bolster research and development.
Corporate Achievements: Recent corporate milestones include the company's uplisting from the OTC Pink Market to the OTCQB Venture Market, enhancing visibility and access to capital. Peak Bio has also filed provisional patent applications to protect its Thailanstatin payload platform, further solidifying its intellectual property portfolio.
Financial and Strategic Outlook: With a strong financial position and strategic partnerships, Peak Bio is poised for significant growth. The company’s proprietary ADC technology continues to attract interest from potential collaborators, and its focus on unmet medical needs positions it as a leader in biopharmaceutical innovation. The recent merger agreement with Akari Therapeutics, which prioritizes Peak Bio's ADC platform and Akari's PAS-nomacopan GA program, underscores the company's commitment to advancing groundbreaking therapies.
For the latest updates and more detailed information, visit Peak Bio's official website.
Akari Therapeutics and Peak Bio have announced a portfolio prioritization plan for their combined merger entity, focusing on Peak's ADC cancer therapeutic platform technology and Akari's PAS-nomacopan for Geographic Atrophy. The prioritization aims to secure business development opportunities and funding while advancing these critical programs.
Peark Bio, Inc. (NASDAQ: PKBO) has signed a Common Stock Purchase Agreement with White Lion Capital to access up to
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