STOCK TITAN

Vaxcyte, Inc. - PCVX STOCK NEWS

Welcome to our dedicated page for Vaxcyte news (Ticker: PCVX), a resource for investors and traders seeking the latest updates and insights on Vaxcyte stock.

Vaxcyte, Inc. (Nasdaq: PCVX) is a pioneering biopharmaceutical company based in San Carlos, California, dedicated to developing high-fidelity vaccines to protect against serious bacterial infections. Vaxcyte aims to improve global health through innovative vaccines designed to prevent diseases that conventional options fail to address effectively.

The company's flagship product, VAX-24, is a 24-valent pneumococcal conjugate vaccine (PCV) designed to provide broad-spectrum protection against invasive pneumococcal disease (IPD). VAX-24 is engineered to cover more strains than the current leading vaccines, addressing a significant unmet need in both adult and pediatric populations. Vaxcyte's advanced cell-free protein synthesis platform, XpressCF™, is pivotal in developing these complex conjugate vaccines, allowing for efficient production and enhanced immunogenicity.

Vaxcyte's pipeline includes VAX-31, a next-generation 31-valent PCV, currently in Phase 1/2 clinical trials. VAX-31 aims to achieve the broadest coverage of any PCV to date, targeting 95% of IPD strains circulating in the U.S. adult population. Additionally, the company is developing other promising vaccine candidates such as VAX-A1 for Group A Strep infections, VAX-PG for periodontal disease, and VAX-GI for Shigella prevention.

Recent milestones include the successful completion of enrollment in the VAX-31 Phase 1/2 trial and the VAX-24 infant Phase 2 study. The FDA granted Breakthrough Therapy designation to VAX-24, reflecting its potential to offer substantial improvements over existing treatments. Vaxcyte is on track to advance VAX-24 into Phase 3 trials, with topline data anticipated by 2025.

Financially, Vaxcyte is robust, supported by $1.4 billion in recent follow-on equity financings to advance its vaccine candidates and expand its manufacturing capabilities.

For more information, visit www.vaxcyte.com.

Rhea-AI Summary
Vaxcyte, Inc. (Nasdaq: PCVX) announced the ongoing Phase 2 study of VAX-24 in healthy infants advanced to the second and final stage of the study, dosing the first new participants in July 2023. The company's lead, broad-spectrum 24-valent pneumococcal conjugate vaccine (PCV) candidate, demonstrated robust opsonophagocytic activity (OPA) immune responses across all 24 serotypes in adults aged 65 and older. The six-month safety data from both studies showed safety and tolerability results for VAX-24 similar to PCV20 at all doses studied. Additionally, Vaxcyte completed a successful $575 million follow-on financing and published new VAX-GI preclinical data, receiving NIH grants. The company's cash, cash equivalents, and investments were $1.4 billion as of June 30, 2023, including net proceeds of $545.3 million from April's public offering.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-3.93%
Tags
-
-
Rhea-AI Summary
Vaxcyte, Inc. to participate in a fireside chat at Jefferies Healthcare Conference
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
0.85%
Tags
conferences
Rhea-AI Summary
Vaxcyte announces positive results from Phase 2 study of VAX-24 in adults aged 65 and older, confirms clinical potential of lead vaccine candidate. Full safety data shows similar results to PCV20. Dosed first participants in infant Phase 2 study. $949.9 million in cash as of March 31, 2023.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
4.76%
Tags
-
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-0.22%
Tags
conferences
-
Rhea-AI Summary

Vaxcyte, Inc. (Nasdaq: PCVX) successfully closed its public offering of 13,030,000 shares of common stock at a price of $41.00 each, along with pre-funded warrants for 1,000,000 shares at $40.999 per share. This offering raised approximately $575 million in gross proceeds before expenses. The underwriting team, including BofA Securities and Jefferies, fully exercised an option for an additional 1,830,000 shares. These funds will support Vaxcyte's mission in developing innovative vaccines for bacterial diseases, including its lead candidate, VAX-24, aimed at preventing invasive pneumococcal disease. Vaxcyte utilizes a unique cell-free protein synthesis platform to enhance vaccine production efficiency.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-3.86%
Tags
Rhea-AI Summary

Vaxcyte, Inc. (Nasdaq: PCVX) has announced a public offering of 11,200,000 shares of common stock and pre-funded warrants for approximately $500 million in gross proceeds. The common stock is priced at $41.00 per share, while pre-funded warrants are priced at $40.999 each, with an exercise price of $0.001. The offering is set to close on April 21, 2023, subject to customary conditions. The underwriters have an option to purchase up to an additional 1,830,000 shares. This capital raise aims to support Vaxcyte's ongoing development of innovative vaccines, including its lead candidate, VAX-24, targeting invasive pneumococcal disease. Vaxcyte's technology leverages advanced synthetic techniques to enhance vaccine efficacy.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
3.83%
Tags
-
Rhea-AI Summary

Vaxcyte, Inc. (Nasdaq: PCVX) has initiated an underwritten public offering of its common stock and pre-funded warrants, seeking to raise capital to support its innovative vaccine initiatives. The offering will include an option for underwriters to buy an additional 15% of shares. The financial details of the offering are not yet disclosed, and the completion will depend on market conditions. BofA Securities, Jefferies, SVB Securities, Evercore ISI, and Guggenheim Securities are the joint book-running managers for this offering. The company has a robust pipeline focusing on vaccines to combat bacterial diseases, including its lead candidate VAX-24, a 24-valent pneumococcal conjugate vaccine. This offering is designed to further strengthen Vaxcyte’s position in the vaccine market.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
4.16%
Tags
-
Rhea-AI Summary

Vaxcyte, Inc. (PCVX) announced positive results from the VAX-24 Phase 2 study in adults aged 65 and older, confirming robust opsonophagocytic activity (OPA) immune responses across all 24 serotypes. The VAX-24 2.2mcg dose met non-inferiority criteria for 18 of 20 serotypes common with Prevnar 20 and demonstrated superior responses for four additional serotypes. Six-month safety data indicated similar safety and tolerability results compared to Prevnar 20. Vaxcyte plans to advance VAX-24 to a Phase 3 study, with topline data expected in 2025. The data supports VAX-24's potential as a best-in-class pneumococcal conjugate vaccine (PCV), aiming to reduce the incidence of invasive pneumococcal disease (IPD) among adults.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
16%
Tags
Rhea-AI Summary

Vaxcyte, Inc. (Nasdaq: PCVX) will host a webcast and conference call on April 17, 2023, at 7:30 a.m. ET to discuss results from its Phase 2 study of VAX-24, a 24-valent pneumococcal conjugate vaccine candidate, targeting adults aged 65 and older. The discussion will include detailed six-month safety data from adult Phase 2 studies. VAX-24 aims to provide broad-spectrum protection against invasive pneumococcal diseases. Vaxcyte is utilizing modern synthetic techniques like the XpressCF™ cell-free protein synthesis platform to create high-fidelity vaccines efficiently. The company's pipeline also features candidates such as VAX-31, VAX-A1, VAX-PG, and VAX-GI, addressing various bacterial infections.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
16%
Tags
conferences clinical trial

FAQ

What is the current stock price of Vaxcyte (PCVX)?

The current stock price of Vaxcyte (PCVX) is $88.54 as of November 22, 2024.

What is the market cap of Vaxcyte (PCVX)?

The market cap of Vaxcyte (PCVX) is approximately 11.2B.

What is Vaxcyte, Inc.'s primary focus?

Vaxcyte is focused on developing broad-spectrum conjugate and novel protein vaccines to prevent or treat bacterial infectious diseases.

What are the key products in Vaxcyte's pipeline?

Vaxcyte's key products include VAX-24, a 24-valent pneumococcal conjugate vaccine, and VAX-31, a 31-valent PCV, along with other candidates like VAX-A1, VAX-PG, and VAX-GI.

What makes VAX-24 different from existing vaccines?

VAX-24 is designed to provide broader protection against more pneumococcal strains compared to current vaccines, addressing significant unmet needs in both adults and children.

What is the XpressCF™ platform?

XpressCF™ is Vaxcyte's cell-free protein synthesis platform that allows efficient production of complex vaccines with enhanced immunogenic benefits.

What recent milestones has Vaxcyte achieved?

Recent milestones include the completion of enrollment in the VAX-31 Phase 1/2 trial and the VAX-24 infant Phase 2 study, along with FDA Breakthrough Therapy designation for VAX-24.

When is Vaxcyte expected to release data from its VAX-24 Phase 3 trials?

Vaxcyte plans to release topline data from the VAX-24 Phase 3 trials by 2025.

What financial support does Vaxcyte have for its projects?

Vaxcyte is financially supported by recent equity financings totaling approximately $1.4 billion.

Where can I find more information about Vaxcyte?

For more information, you can visit Vaxcyte's official website at www.vaxcyte.com.

What is VAX-31 and its significance?

VAX-31 is a 31-valent pneumococcal conjugate vaccine aiming to cover 95% of invasive pneumococcal disease strains in the U.S. adult population, representing the broadest coverage in PCV candidates.

What other vaccine candidates is Vaxcyte developing?

Besides VAX-24 and VAX-31, Vaxcyte is developing VAX-A1 for Group A Strep, VAX-PG for periodontal disease, and VAX-GI for Shigella.

Vaxcyte, Inc.

Nasdaq:PCVX

PCVX Rankings

PCVX Stock Data

11.22B
120.71M
0.51%
111.91%
7.17%
Biotechnology
Biological Products, (no Disgnostic Substances)
Link
United States of America
SAN CARLOS