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Passage Bio, Inc. - PASG STOCK NEWS

Welcome to our dedicated page for Passage Bio news (Ticker: PASG), a resource for investors and traders seeking the latest updates and insights on Passage Bio stock.

Passage Bio, Inc. (NASDAQ: PASG) is a pioneering genetic medicines company dedicated to the development of transformative therapies for rare monogenic central nervous system (CNS) diseases. Leveraging cutting-edge gene therapy techniques, Passage Bio is advancing a robust pipeline aimed at addressing unmet medical needs in both pediatric and adult CNS disorders.

The company's key initiatives include the development of PBGM01 for infantile GM1 gangliosidosis, PBFT02 for frontotemporal dementia (FTD) caused by progranulin deficiency, and PBKR03 for infantile Krabbe disease. These therapies utilize proprietary adeno-associated virus (AAV) capsids to deliver functional genes directly to the brain and peripheral tissues, promising significant therapeutic benefits.

Passage Bio collaborates with leading institutions to bolster its research and development efforts. This includes a strategic research partnership with the University of Pennsylvania's Gene Therapy Program and a collaboration agreement with Catalent Maryland, Inc. Such alliances enhance Passage Bio's capacity to innovate and expedite the clinical development of its promising therapies.

Financially, Passage Bio is in a strong position, with a cash runway extending into the fourth quarter of 2025, allowing the company to diligently progress its clinical programs. Recent achievements include positive interim data from the Imagine-1 study, a Phase 1/2 clinical trial of PBGM01, demonstrating a favorable safety profile and initial evidence of efficacy in early and late infantile GM1 gangliosidosis.

Additionally, the company is making strides with PBFT02. Initial data from the upliFT-D clinical trial indicate promising safety and biomarker outcomes, showing elevated cerebrospinal fluid (CSF) progranulin levels. Such results underscore the potential of PBFT02 to address the underlying pathology of FTD and other neurodegenerative conditions.

Passage Bio is also committed to fostering the next generation of scientists through initiatives like the Tachi Yamada Scholarship program, which supports students in life sciences disciplines.

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Passage Bio, Inc. (Nasdaq: PASG) grants 10,400 shares of common stock as an inducement award to a new employee, in accordance with Nasdaq Listing Rule 5635(c)(4). The options have an exercise price of $0.628 per share, equal to the closing price on November 15, 2023. The shares will vest over four years, with 25% vesting after one year, and the remainder in 36 equal monthly installments, subject to continued employment.
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Passage Bio, Inc. (PASG) reports progress in clinical trials for FTD and GM1 treatment, with a strong financial position and extended cash runway. The company expects to present initial safety and biomarker data from three Cohort 1 patients in the upliFT-D trial for FTD in Q4 2023 and from Dose 3 patients in the Imagine-1 trial for GM1 in mid-2024. With a robust balance sheet, Passage Bio is well-positioned to achieve meaningful clinical milestones.
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Passage Bio, Inc. (NASDAQ: PASG) announced that its CEO, William Chou, will participate in a fireside chat at Guggenheim’s 5th Annual Inflammation, Neurology & Immunology Conference on November 6, 2023 at 2:30 p.m. ET. The event will be webcasted live on Passage Bio's website.
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Passage Bio grants inducement awards to new employees
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Passage Bio's CEO to participate in fireside chat at Chardan's Genetic Medicines Conference
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Passage Bio announces new interim safety, biomarker, and survival data from the Imagine-1 clinical study. Dose 2 of PBGM01 shows substantial improvements in CSF biomarkers and achieves normal levels of CSF β-Gal activity and GM1 gangliosides. Initial evidence of improved survival relative to natural history data. Dose 3 data expected by mid-2024.
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Passage Bio, Inc. (Nasdaq: PASG) announces the appointment of Dr. Dolan Sondhi to the Board of Directors and her role in the Nominating and Corporate Governance Committee. Dr. Sondhi brings extensive experience in AAV gene therapy research and neurodegenerative diseases, aligning with Passage Bio's mission to develop transformative therapies for CNS disorders.
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FAQ

What is the current stock price of Passage Bio (PASG)?

The current stock price of Passage Bio (PASG) is $0.66 as of December 20, 2024.

What is the market cap of Passage Bio (PASG)?

The market cap of Passage Bio (PASG) is approximately 39.5M.

What does Passage Bio, Inc. specialize in?

Passage Bio, Inc. specializes in developing transformative gene therapies for rare monogenic central nervous system (CNS) diseases.

What are some of the key products in Passage Bio’s pipeline?

Key products include PBGM01 for GM1 gangliosidosis, PBFT02 for frontotemporal dementia, and PBKR03 for infantile Krabbe disease.

Who are Passage Bio’s key collaborators?

Passage Bio collaborates with the University of Pennsylvania's Gene Therapy Program and Catalent Maryland, Inc.

What is the focus of the Imagine-1 clinical study?

Imagine-1 is a Phase 1/2 study evaluating the safety and efficacy of PBGM01 for treating early and late infantile GM1 gangliosidosis.

What recent advancements has Passage Bio made?

Recent advancements include positive interim data from the Imagine-1 study and promising initial results from the upliFT-D trial for PBFT02.

What is PBGM01?

PBGM01 is a gene therapy designed to treat infantile GM1 gangliosidosis by delivering a functional GLB1 gene using an AAVhu68 capsid.

What is the purpose of the Tachi Yamada Scholarship program?

The Tachi Yamada Scholarship program supports life sciences students in Pennsylvania, fostering the next generation of scientists.

When does Passage Bio expect to release additional data from their clinical trials?

Passage Bio plans to release additional data from ongoing clinical trials throughout 2024, including further safety and efficacy updates.

What are the financial highlights of Passage Bio?

Passage Bio has extended its cash runway into Q4 2025, reflecting strong financial health to support ongoing clinical programs.

What is PBFT02 and what conditions does it target?

PBFT02 is a gene therapy aimed at treating frontotemporal dementia (FTD) by elevating progranulin levels to restore lysosomal function.

Passage Bio, Inc.

Nasdaq:PASG

PASG Rankings

PASG Stock Data

39.52M
51.80M
0.49%
59.68%
2.66%
Biotechnology
Biological Products, (no Disgnostic Substances)
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United States of America
PHILADELPHIA