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Volta Labs joins PacBio Compatible program to help PacBio customers scale sequencing through automated library prep

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Volta Labs has joined the PacBio Compatible program, strengthening their partnership to provide automated library preparation solutions for PacBio sequencing customers. The collaboration centers on the Callisto Sample Prep System, which enables automated preparation of PacBio HiFi libraries with minimal hands-on time (less than 30 minutes) and 5.5 hours of walk-away time. The system supports batch sizes from 4-24 reactions and offers high yield at half-scale reactions. Recent data presented at a Genomeweb webinar demonstrated the system's impact on scaling PacBio sequencing operations, particularly benefiting organizations from core labs to biotech companies.

Volta Labs si è unita al programma compatibile con PacBio, rafforzando la loro partnership per fornire soluzioni automatizzate di preparazione delle librerie per i clienti di sequenziamento PacBio. La collaborazione si concentra sul Callisto Sample Prep System, che consente una preparazione automatizzata delle librerie PacBio HiFi con un tempo di intervento minimo (meno di 30 minuti) e 5,5 ore di tempo libero. Il sistema supporta dimensioni dei lotti da 4 a 24 reazioni e offre un'alta resa a reazioni di scala ridotta. Dati recenti presentati in un webinar di Genomeweb hanno dimostrato l'impatto del sistema sulla scalabilità delle operazioni di sequenziamento PacBio, beneficiando in particolare organizzazioni che vanno dai laboratori centralizzati alle aziende biotecnologiche.

Volta Labs se ha unido al programa compatible con PacBio, fortaleciendo su colaboración para proporcionar soluciones automatizadas de preparación de bibliotecas para los clientes de secuenciación de PacBio. La colaboración se centra en el Callisto Sample Prep System, que permite la preparación automatizada de bibliotecas PacBio HiFi con un tiempo de intervención mínimo (menos de 30 minutos) y 5,5 horas de tiempo sin supervisión. El sistema admite tamaños de lotes de 4 a 24 reacciones y ofrece un alto rendimiento en reacciones de escala reducida. Datos recientes presentados en un seminario web de Genomeweb demostraron el impacto del sistema en la escalabilidad de las operaciones de secuenciación de PacBio, beneficiando especialmente a organizaciones que van desde laboratorios centrales hasta empresas biotecnológicas.

볼타랩스PacBio 호환 프로그램에 합류하여 PacBio 염기서열 분석 고객을 위한 자동화된 라이브러리 준비 솔루션을 제공하는 파트너십을 강화했습니다. 이번 협력은 칼리스토 샘플 준비 시스템에 초점을 맞추고 있으며, 이는 최소한의 수작업 시간(30분 미만)과 5.5시간의 자율 시간을 갖고 PacBio HiFi 라이브러리를 자동으로 준비할 수 있게 해줍니다. 이 시스템은 4-24 반응의 배치 크기를 지원하며, 반응의 절반 크기에서 높은 수율을 제공합니다. Genomeweb 웨비나에서 발표된 최근 데이터는 PacBio 염기서열 분석 작업의 확장에 대한 시스템의 영향을 보여주었으며, 특히 핵심 실험실에서 생명공학 회사까지 다양한 조직에 혜택을 줍니다.

Volta Labs a rejoint le programme compatible avec PacBio, renforçant ainsi leur partenariat pour fournir des solutions automatisées de préparation de bibliothèques pour les clients de séquençage PacBio. La collaboration se concentre sur le Système de préparation d'échantillons Callisto, qui permet la préparation automatisée de bibliothèques PacBio HiFi avec un temps d'intervention minimal (moins de 30 minutes) et 5,5 heures de temps libre. Le système prend en charge des tailles de lot de 4 à 24 réactions et offre un rendement élevé lors de réactions à moitié échelle. Des données récentes présentées lors d'un webinaire de Genomeweb ont démontré l'impact du système sur l'évolutivité des opérations de séquençage PacBio, bénéficiant particulièrement aux organisations allant des laboratoires centraux aux entreprises biopharmaceutiques.

Volta Labs hat sich dem PacBio-kompatiblen Programm angeschlossen und stärkt damit die Partnerschaft, um automatisierte Bibliotheksvorbereitungs-Lösungen für PacBio-Sequenzierungskunden anzubieten. Die Zusammenarbeit konzentriert sich auf das Callisto Sample Prep System, das eine automatisierte Vorbereitung von PacBio HiFi-Bibliotheken mit minimalem manuellem Aufwand (weniger als 30 Minuten) und 5,5 Stunden ununterbrochener Zeit ermöglicht. Das System unterstützt Batch-Größen von 4-24 Reaktionen und bietet hohe Ausbeuten bei halbseitigen Reaktionen. Jüngste Daten, die in einem Webinar von Genomeweb präsentiert wurden, zeigten die Auswirkungen des Systems auf die Skalierung von PacBio-Sequenzierungsoperationen, was besonders Organisationen von Kernlaboren bis hin zu Biotechnologieunternehmen zugutekommt.

Positive
  • Automation reduces hands-on library prep time to less than 30 minutes
  • System supports flexible batch processing of 4-24 reactions
  • High yield achieved at half-scale reactions, potentially reducing operational costs
  • Platform enables inexperienced users to generate high-quality libraries with minimal training
Negative
  • None.

Insights

The partnership between Volta Labs and PacBio represents an incremental operational improvement rather than a transformative business development. While the Callisto Sample Prep System offers efficiency gains by reducing library prep time from manual processes to 30 minutes hands-on time and 5.5 hours walk-away time, this automation solution primarily addresses workflow optimization rather than expanding market reach or revenue potential.

The technology streamlines existing processes for current customers but doesn't fundamentally alter PacBio's competitive position or market dynamics. The compatibility program addition enhances customer experience through automation but likely won't significantly impact PacBio's financial performance or market share in the sequencing industry. The focus on operational efficiency aligns with industry trends but represents an expected evolution rather than a market-moving development.

BOSTON, Oct. 30, 2024 /PRNewswire/ -- Volta Labs™, a genomics applications company, announced today that it has joined the PacBio Compatible program, further expanding the partnership between Volta Labs and PacBio.

Volta Labs is partnering with PacBio to offer walk-away automation for PacBio library prep, enabling labs to scale sample prep for sequencing. Through preloaded apps on the Callisto™ Sample Prep System, a push-button sample prep solution for all NGS sequencing needs, PacBio customers can prepare high-quality PacBio HiFi libraries with less than 30 minutes of hands-on time and 5.5 hours of walk-away time.

"We're thrilled to welcome Volta, and specifically the Callisto platform, into the PacBio compatible program. Thanks to Volta's Callisto automation system, PacBio customers can now benefit from a streamlined library prep process, significantly reducing hands-on and setup time which in turn allows labs to focus more on sequencing and discovery rather than manual prep. This simplification aligns with where we at PacBio have been focusing our library prep innovations and supports our mission to make high-quality sequencing accessible and scalable for all," said David Miller, VP of Global Marketing at PacBio.

The announcement comes shortly after a recent Genomeweb webinar where Greg Young, senior product manager at PacBio, joined Maya Fridrikh, PacBio sequencing manager at the Icahn School of Medicine at Mount Sinai, to unveil new data showing the impact of Volta Labs library prep automation to scale PacBio sequencing. Callisto's walk-away operation supports flexible batch sizes from 4-24 reactions, with high yield at half-scale reactions. The VoltaPrep™ app for PacBio SMRTbell Libraries has proven to positively impact operational costs and efficiency, for organizations ranging from core labs to biotech companies.

"PacBio library prep can be challenging for many labs, especially those suffering from resource constraints. With Callisto, even inexperienced users can be trained in minutes to generate high-quality PacBio libraries with minimal inter-operator variability," said Udayan Umapathi, founder and CEO of Volta Labs. "We have been collaborating with the PacBio team for quite a while, and their recognition of Volta as a compatible partner is a big step forward for sample prep automation."

PacBio Compatible works with a wide range of organizations to ensure customers can find verified products that are complementary to their workflows for PacBio sequencing. Partners like Volta Labs collaborate closely with PacBio scientists to provide seamless integration and support for customers who are just starting out with PacBio or expanding their current capabilities.

About Volta Labs
Volta Labs is a genomics applications company that has developed a cutting-edge digital fluidics platform to maximize performance and scalability of sample preparation in genomics while providing unparalleled consistency. Volta Labs is transforming the way biological research and analyses are performed, allowing scientists to focus on what they do best -- pushing the boundaries of biology.

About PacBio
PacBio (NASDAQ: PACB) is a premier life science technology company that is designing, developing and manufacturing advanced sequencing solutions to help scientists and clinical researchers resolve genetically complex problems. Our products and technologies stem from two highly differentiated core technologies focused on accuracy, quality and completeness which include our HiFi long-read sequencing and our SBB® short-read sequencing technologies. Our products address solutions across a broad set of research applications including human germline sequencing, plant and animal sciences, infectious disease and microbiology, oncology, and other emerging applications. For more information, please visit www.pacb.com and follow @PacBio.

Media Contact:
Kim Miller
Volta Labs
kmiller@voltalabs.co

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SOURCE Volta Labs Inc.

FAQ

What is the hands-on time for PacBio library prep using Volta Labs' Callisto System?

The Callisto Sample Prep System requires less than 30 minutes of hands-on time and 5.5 hours of walk-away time for PacBio library preparation.

How many reactions can the Volta Labs Callisto system process for PACB libraries?

The Callisto system supports flexible batch sizes ranging from 4 to 24 reactions for PacBio library preparation.

What are the benefits of Volta Labs' automation for PACB sequencing?

Benefits include reduced hands-on time, support for flexible batch sizes, high yield at half-scale reactions, minimal inter-operator variability, and easy training for inexperienced users.

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