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Nuvectis Pharma, Inc. - NVCT STOCK NEWS

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Nuvectis Pharma, Inc. (NASDAQ: NVCT) is a clinical-stage biopharmaceutical company dedicated to developing innovative precision medicines for treating serious conditions of unmet medical need in oncology. The company's core focus lies in the development of novel small molecule therapeutics targeting genetically defined patient populations in cancer.

Nuvectis Pharma’s pipeline includes two promising drug candidates, NXP800 and NXP900. NXP800 is an oral small molecule currently in a Phase 1b clinical trial for the treatment of platinum-resistant, ARID1a-mutated ovarian carcinoma. The U.S. Food and Drug Administration (FDA) has granted Fast Track Designation to the NXP800 program for this indication and Orphan Drug Designation for the treatment of cholangiocarcinoma. Recently, Nuvectis announced a collaboration with Mayo Clinic to evaluate NXP800 in an investigator-sponsored clinical trial for cholangiocarcinoma.

NXP900, on the other hand, is a novel small molecule SRC/YES1 kinase inhibitor currently undergoing a Phase 1a dose escalation study. NXP900 has shown potential as a standalone treatment and in combination with other therapies in preclinical studies, particularly in non-small cell lung cancer (NSCLC) resistant to EGFR inhibitors like osimertinib and ALK inhibitors like alectinib.

Financially, Nuvectis remains robust, with cash and cash equivalents of $19.1 million as of December 31, 2023. However, the company recorded a net loss of $22.3 million for the same period, largely due to its focused investment in research and development. Despite this, the company maintains a cash-efficient strategy, ensuring sufficient runway to continue its critical work.

In 2024, Nuvectis anticipates several key clinical milestones, including updates from ongoing trials of NXP800 and NXP900. The company is positioned as a significant player in the biopharmaceutical landscape, driven by its commitment to addressing unmet medical needs in oncology through precision medicine.

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Nuvectis Pharma (NASDAQ: NVCT) will participate in the H.C. Wainwright 2nd BioConnect Investor Conference.

CEO Ron Bentsur will present on May 20, 2024, at 12:00 PM Eastern Time at NASDAQ headquarters in NYC.

As a clinical-stage biopharmaceutical company, Nuvectis focuses on developing precision medicines for serious oncology conditions with unmet medical needs.

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Nuvectis Pharma, Inc. reported encouraging preliminary data from the NXP800 Phase 1b study in platinum resistant, ARID1a-mutated ovarian cancer and robust activity of NXP900 in non-small cell cancer cell lines. Several clinical data updates are expected in the second half of 2024. The company remains cash flow efficient with approximately $19.5 million in cash, providing runway into the second half of 2025. Financially, cash and cash equivalents increased to $19.5 million from $19.1 million, with a net loss of $4.2 million for the first quarter of 2024, including $1.3 million in non-cash stock-based compensation.

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Nuvectis Pharma, Inc. (NVCT) presented promising data at the AACR conference regarding NXP900's synergistic antiproliferative activity in EGFR and ALK-resistant NSCLC cells when combined with osimertinib and alectinib. The study showed a reversal of resistance to these inhibitors, with potent single-agent activity of NXP900. The CEO highlighted the importance of overcoming treatment resistance in NSCLC patients.
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Nuvectis Pharma, Inc. (NVCT) announces presentations for NXP800 and NXP900 at the 2024 AACR Meeting. NXP800 shows promise in treating ovarian cancer, while NXP900 demonstrates antitumor activity in cholangiocarcinoma models.
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Nuvectis Pharma to present at the 36th Annual Roth Conference on March 19, 2024, focusing on precision medicines for oncology.
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Nuvectis Pharma, Inc. (NVCT) announces positive preliminary data from Phase 1b clinical trial of NXP800 in platinum resistant ARID1a-mutated ovarian cancer patients. Results show a 33% response rate and 100% disease control rate. Fast Track Designation granted by FDA. Encouraging efficacy data observed in early patients, with manageable side effects.
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Nuvectis Pharma, Inc. provided an update on its two clinical-stage drug candidates, NXP800 and NXP900, with multiple clinical data readouts expected in 2024. The company reported a decrease in cash and cash equivalents, a net loss increase of $2.2 million, and higher research and development expenses in the fiscal year 2023.
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Nuvectis Pharma, Inc. (NVCT) announced that Ron Bentsur will present at investor conferences, including Oppenheimer Healthcare Life Sciences Conference and NeauxCancer Oncology Conference.
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Nuvectis Pharma, Inc. (NVCT) announces Ron Bentsur, Chairman and CEO, will present at investor conferences. The company focuses on precision medicines for oncology.
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Nuvectis Pharma, Inc. (NASDAQ: NVCT) announced that Ron Bentsur, Chairman and CEO, will present at the 42nd Annual J.P. Morgan Healthcare Conference on January 8, 2024, to discuss the development of precision medicines for serious conditions in oncology.
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FAQ

What is the current stock price of Nuvectis Pharma (NVCT)?

The current stock price of Nuvectis Pharma (NVCT) is $4.52 as of December 20, 2024.

What is the market cap of Nuvectis Pharma (NVCT)?

The market cap of Nuvectis Pharma (NVCT) is approximately 89.3M.

What does Nuvectis Pharma, Inc. specialize in?

Nuvectis Pharma specializes in developing innovative precision medicines for the treatment of serious conditions of unmet medical need in oncology.

What are Nuvectis Pharma's main drug candidates?

The main drug candidates are NXP800, an oral small molecule for platinum-resistant, ARID1a-mutated ovarian carcinoma, and NXP900, a SRC/YES1 kinase inhibitor for various cancer indications.

What recent collaborations has Nuvectis Pharma announced?

Nuvectis recently announced a collaboration with Mayo Clinic to evaluate NXP800 in an investigator-sponsored clinical trial for cholangiocarcinoma.

What designations has the FDA granted to NXP800?

The FDA has granted Fast Track Designation for NXP800 in platinum-resistant, ARID1a-mutated ovarian carcinoma, and Orphan Drug Designation for cholangiocarcinoma.

What is the financial condition of Nuvectis Pharma?

As of December 31, 2023, Nuvectis had $19.1 million in cash and cash equivalents, with a net loss of $22.3 million for the year.

What are the expected milestones for Nuvectis Pharma in 2024?

Nuvectis expects several key clinical milestones, including updates from ongoing trials of NXP800 and NXP900.

Who is the CEO of Nuvectis Pharma?

Ron Bentsur is the Chairman, Chief Executive Officer, and President of Nuvectis Pharma.

Where is Nuvectis Pharma headquartered?

Nuvectis Pharma is headquartered in Fort Lee, New Jersey.

What recent clinical data was released regarding NXP800?

Preliminary data from the Phase 1b clinical trial of NXP800 in platinum-resistant, ARID1a-mutated ovarian carcinoma showed a 33% response rate and a 100% disease control rate.

How is NXP900 being evaluated in preclinical studies?

NXP900 has demonstrated potent activity as a single agent and in combination with other therapies in preclinical studies, especially in NSCLC resistant to EGFR and ALK inhibitors.

Nuvectis Pharma, Inc.

Nasdaq:NVCT

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89.26M
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51.52%
6.97%
7.22%
Biotechnology
Pharmaceutical Preparations
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United States of America
FORT LEE