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NKGen Biotech, Inc. (symbol: NKGN) is a progressive biotechnology company dedicated to developing cutting-edge cell therapies aimed at combating neurodegenerative and oncological diseases. The company’s central focus revolves around utilizing activated NK cells, which form a part of the human innate immune response system. These cells have the remarkable ability to selectively identify and eliminate abnormal or diseased cells.
NKGen Biotech’s innovative approach is anchored in a proprietary manufacturing and cryopreservation process that produces SuperNK™ (SNK) cells. These cells exhibit significantly enhanced activity compared to the original population of NK cells. Enhanced parameters include increased cytotoxicity, cytokine production, and activating receptor expression, based on detailed in vitro experiments conducted by NKMAX. One of the notable advantages of SNK cells is their ability to be produced in large quantities and preserved cryogenically without losing their high levels of cytotoxicity.
Recently, NKGen Biotech has achieved significant milestones with its SNK01 trial. Additional Phase 1 data point to clinical activity regarding cognitive function in patients with advanced Alzheimer’s disease, alongside previously disclosed positive effects on amyloid protein and neuroinflammation biomarkers. Dr. Jesse Carr, MD, Medical Director of Behavioral Research Specialists, LLC, has expressed optimism about the trial, highlighting the absence of treatment-related adverse events and noting apparent improvements in patients' cognitive function, daily living activities, and overall quality of life.
For investors and stakeholders, NKGen Biotech represents a beacon of innovation in the biotechnology sector, with its unique approach to developing cell therapies that could potentially redefine the treatment landscape for challenging diseases like Alzheimer’s and various cancers. The company’s robust pipeline, strategic partnerships, and ongoing clinical trials position it as a key player in advancing medical science and therapeutic solutions.
For the latest updates and detailed information, visit the NKGen Biotech website.
NKGen Biotech, a clinical-stage biotech company, will present its autologous NK cell therapy, SNK01, at the 5th International Cell & Gene Therapy China Summit. SNK01, which shows enhanced cytotoxicity and receptor expression, targets neurodegenerative diseases and solid tumors. CEO Paul Y. Song will discuss manufacturing advances and results combining SNK01 with immune checkpoint inhibitors and Erbitux for resistant cancers. The presentation, set for May 23, 2024, will also highlight SNK01's potential against multiple neurodegenerative diseases by improving key protein levels.
NKGen Biotech, Inc. (NKGN) received FDA clearance for its SNK01 NK cell therapy in Parkinson's disease, advancing its neurodegenerative disease program. The Phase 1/2a clinical trial is set to commence in 2H 2024, with SNK01 showing promising potential in addressing Parkinson's disease through enhanced cytotoxicity and activating receptor expression.