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NexImmune, Inc. (Nasdaq: NEXI) is an emerging biopharmaceutical company focused on advancing a new generation of immunotherapies using its proprietary Artificial Immune Modulation (AIM™) technology platform. Originally developed at Johns Hopkins University, AIM™ technology harnesses the body’s immune system to orchestrate a targeted T cell response against diseases.
The cornerstone of NexImmune’s innovation is the development of artificial antigen-presenting cells (aAPCs). These aAPCs present specific antigens to T cells, which in turn stimulate a highly targeted immune response. This approach can be rapidly customized to direct immune attacks toward various foreign substances or diseased cells within the patient's body. The company is currently working on therapies aimed at treating cancer and other serious immune-mediated conditions.
NexImmune has two key product candidates in clinical trials: NEXI-001, for treating acute myeloid leukemia (AML), and NEXI-002, for multiple myeloma (MM). These candidates leverage the curative potential of the body’s own T cells, engineered to target and destroy specific cancer cells.
Recent Highlights:
Clinical and Preclinical Updates: NexImmune announced significant progress in generating pre-clinical data supporting their multi-antigen-specific T cell-directing products. This includes validation from collaborators at leading institutions, underlining the transformative potential of their AIM technology.
Financial Highlights: The company recently reported select second-quarter 2023 financial results, showcasing a focus on core capabilities while managing operational flexibility through workforce adjustments.
Partnerships: NexImmune extended its research collaboration with Yale University and JDRF. This partnership aims to explore the use of NexImmune’s AIM nanoparticles combined with anti-CD3 mAb for potential type 1 diabetes treatments. The extension includes an additional $300,000 grant provided by JDRF.
In October 2023, NexImmune executed a 1-for-25 reverse stock split, reducing its outstanding shares and addressing compliance with Nasdaq’s minimum bid price requirement. The company remains dedicated to advancing its innovative therapeutic candidates and remains a significant player in the field of immuno-oncology and beyond.
For more information, visit www.neximmune.com.
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