Welcome to our dedicated page for NewAmsterdam Pharma Company N.V news (Ticker: NAMS), a resource for investors and traders seeking the latest updates and insights on NewAmsterdam Pharma Company N.V stock.
NewAmsterdam Pharma Company N.V. (Nasdaq: NAMS) is a leading late-stage biopharmaceutical company headquartered in the Netherlands, dedicated to revolutionizing patient care for metabolic diseases. The company focuses on populations where existing therapies are insufficient or poorly tolerated. Central to NewAmsterdam's innovation is obicetrapib, a next-generation, oral, low-dose CETP inhibitor designed to address limitations of current LDL-C lowering treatments.
As of 2024, NewAmsterdam is at the forefront of clinical development, with multiple pivotal Phase 3 trials underway. The company is optimistic about its potential to transform cardiovascular disease (CVD) treatment. Recent milestones include the enrollment completion of the BROOKLYN and BROADWAY Phase 3 trials, both aimed at evaluating obicetrapib’s efficacy as an adjunct to maximally tolerated statin therapy. Additionally, the company's PREVAIL cardiovascular outcomes trial and the newly initiated TANDEM Phase 3 trial are progressing, assessing obicetrapib's combination with ezetimibe for patients with elevated LDL-C levels.
In 2023, NewAmsterdam reported promising outcomes from its Phase 2 trials, including the ROSE2 trial, which combined obicetrapib with ezetimibe, demonstrating a significant 63% reduction in LDL-C levels. The company's robust clinical pipeline showcases obicetrapib’s strong tolerability profile, having tested the drug in over 800 patients with elevated lipid levels and observing statistically significant results without severe adverse events.
Looking to the future, NewAmsterdam is well-positioned financially, forecasting sufficient cash runway through 2026 to support its ambitious development plans. The company is also actively preparing for the global launch of obicetrapib, pending necessary regulatory approvals. This includes strategic investments in its commercial organization to ensure comprehensive market readiness.
NewAmsterdam’s commitment to innovation is further reinforced by strong intellectual property protection for obicetrapib, with patents extending until July 2043. This robust IP portfolio underscores the company's dedication to maintaining a competitive edge in the biopharmaceutical industry.
For more information, visit NewAmsterdam Pharma Company’s investor relations page or contact their media and investor relations teams for the latest updates.
NewAmsterdam Pharma (NAMS) reported its full year 2024 financial results and corporate updates. The company highlighted positive results from three Phase 3 trials for obicetrapib, their oral non-statin medicine for cardiovascular disease patients with elevated LDL-C. The BROADWAY trial showed 33% LDL-C reduction, TANDEM trial achieved 49% reduction, and BROOKLYN trial demonstrated 36% reduction compared to placebo.
Financial highlights include $834.2 million in cash and marketable securities, revenue of $45.6 million (up from $14.1M in 2023), R&D expenses of $151.4 million, and net loss of $241.6 million. The company secured patent protection for obicetrapib until 2043 and expects EMA submission in 2H25 through partner Menarini.
NewAmsterdam Pharma (Nasdaq: NAMS), a late-stage clinical biopharmaceutical company developing oral, non-statin medicines for patients with elevated LDL-C and cardiovascular disease risk, has announced its participation in multiple investor conferences in March 2025.
The company will attend the TD Cowen 45th Annual Healthcare Conference in Boston on March 4-5, where CEO Michael Davidson and CFO Ian Somaiya will present a corporate overview on March 4 at 1:50 p.m. ET.
Additionally, NAMS will participate in the Leerink Partners Global Healthcare Conference in Miami on March 10, with Dr. Davidson presenting at 8:00 a.m. ET, and the Jefferies Biotech on the Beach Summit in Miami on March 12, where management will be available for one-on-one meetings.
Live webcasts of the presentations will be accessible through the investor relations section of the company's website, with archived replays available afterward.
NewAmsterdam Pharma (Nasdaq: NAMS) announced that its Compensation Committee has approved inducement share options for four non-executive new hires. The grants cover 138,000 ordinary shares under the company's 2024 Inducement Plan, complying with Nasdaq Listing Rule 5635(c)(4).
The share options were granted at an exercise price of $21.36, matching the closing market price of NAMS ordinary shares on February 3, 2025. The vesting schedule spans four years, with 25% vesting after one year and the remaining shares vesting in 36 equal monthly installments, contingent on continued employment.
NewAmsterdam Pharma (Nasdaq: NAMS), a late-stage clinical biopharmaceutical company focused on developing oral, non-statin medicines for cardiovascular disease patients with elevated LDL-C, has announced its participation in the Guggenheim SMID Cap Biotech Conference.
The company's Chief Financial Officer, Ian Somaiya, will engage in a fireside chat on Wednesday, February 5, 2025, at 10:00 a.m. ET. Investors and interested parties can access the live webcast through NewAmsterdam Pharma's investor relations website at ir.newamsterdampharma.com. An archived replay will be available on the company's website following the live presentation.
NewAmsterdam Pharma (NAMS) provided updates on its obicetrapib clinical development program and 2025 strategic priorities. The company reported positive topline results from three Phase 3 trials in 2024: BROADWAY showed 33% LDL-C reduction and 21% MACE reduction; TANDEM achieved 49% LDL-C reduction with fixed-dose combination; and BROOKLYN demonstrated 36% LDL-C reduction.
The company completed enrollment of over 9,500 patients in the PREVAIL cardiovascular outcomes trial. Additional data from these trials will be presented throughout 2025, supporting global regulatory filings including EMA submission in 2H25. The Phase 2 VINCENT trial, exploring obicetrapib's effect on Lp(a), is expected to report data in 2H25.
NewAmsterdam ended 2024 with an unaudited cash balance of $835 million following an oversubscribed public offering. The company secured patent protection for obicetrapib until July 2043 and is focusing on commercial readiness with manufacturing capacity establishment.
NewAmsterdam Pharma (Nasdaq: NAMS) announced the approval of inducement grants by its Board's Compensation Committee. The grants include share options for 58,000 ordinary shares to two non-executive new hires and 170,800 ordinary shares to Maryellen McQuade, the new Chief People Officer, at an exercise price of $25.94 per share.
The share options will vest over four years, with 25% vesting after one year and the remainder vesting in 36 monthly installments. Additionally, McQuade received 36,600 restricted stock units that will vest over three years, with one-third vesting annually. These grants were made under the 2024 Inducement Plan in accordance with Nasdaq Listing Rule 5635(c)(4).
Menarini Group announced positive topline data from two Phase 3 trials evaluating Obicetrapib. The BROADWAY trial showed Obicetrapib achieved a 33% LDL-C reduction compared to placebo (p<0.0001), with 50% of patients reaching LDL-C levels below 55 mg/dL. A 21% reduction in major adverse cardiovascular events was observed at one year.
The TANDEM trial, testing a fixed-dose combination of Obicetrapib with Ezetimibe, demonstrated a 48.6% LDL-C reduction (p<0.0001), with over 70% of patients achieving target LDL-C levels. Both treatments were well-tolerated with safety profiles comparable to placebo. These trials are part of a larger Phase 3 program including over 12,250 patients across four studies.
NewAmsterdam Pharma (NAMS) has successfully closed its upsized public offering, raising $479.0 million through the sale of securities. The offering included 14,667,347 ordinary shares at $24.50 per share and pre-funded warrants to purchase 4,882,653 ordinary shares at $24.4999 per warrant. The underwriters fully exercised their option to purchase an additional 2,550,000 ordinary shares.
After deducting underwriting discounts, commissions, and estimated offering expenses, the company received net proceeds of approximately $452.6 million. The offering was conducted through multiple joint book-running managers, including Jefferies, Goldman Sachs, Leerink Partners, TD Cowen, Guggenheim Securities, and William Blair.
NewAmsterdam Pharma (NAMS) has announced the pricing of its upsized public offering, consisting of 12,117,347 ordinary shares at $24.50 per share and pre-funded warrants to purchase 4,882,653 ordinary shares at $24.4999 per warrant. The offering is expected to generate approximately $416.5 million in proceeds before deducting expenses.
The company has granted underwriters a 30-day option to purchase up to an additional 2,550,000 ordinary shares. The offering is expected to close around December 13, 2024. Multiple investment banks, including Jefferies, Goldman Sachs, Leerink Partners, TD Cowen, Guggenheim Securities, and William Blair, are acting as joint book-running managers.
NewAmsterdam Pharma (Nasdaq: NAMS) has announced the commencement of a $300 million public offering of ordinary shares and pre-funded warrants. The company is offering investors the choice between ordinary shares and pre-funded warrants to purchase ordinary shares. Additionally, underwriters will receive a 30-day option to purchase up to an additional $45 million of ordinary shares.
The offering will be conducted through multiple joint book-running managers including Jefferies, Goldman Sachs & Co., Leerink Partners, TD Cowen, Guggenheim Securities, and William Blair. The offering will be made pursuant to a registration statement on Form S-3 that was declared effective by the SEC on July 12, 2024.
FAQ
What is the current stock price of NewAmsterdam Pharma Company N.V (NAMS)?
What is the market cap of NewAmsterdam Pharma Company N.V (NAMS)?
What is NewAmsterdam Pharma Company N.V.'s primary focus?
What is obicetrapib?
What are the key clinical trials NewAmsterdam is conducting?
What significant milestones has NewAmsterdam achieved recently?
How does NewAmsterdam plan to commercialize obicetrapib?
What financial outlook does NewAmsterdam have?
What are NewAmsterdam's goals for 2024?
What is the significance of NewAmsterdam's intellectual property portfolio?
Where is NewAmsterdam Pharma based?
Who should I contact for more information about NewAmsterdam?
