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Matinas Biopharm - MTNB STOCK NEWS

Welcome to our dedicated page for Matinas Biopharm news (Ticker: MTNB), a resource for investors and traders seeking the latest updates and insights on Matinas Biopharm stock.

Company Overview

Matinas Biopharm (MTNB) is a clinical-stage biopharmaceutical company specializing in developing innovative anti-infectives using advanced lipid-crystal nanoparticle cochleate technology. This novel approach focuses on reformulating existing drugs into safer, less toxic, and orally bioavailable forms, addressing significant therapeutic challenges in treating orphan indications and complex infectious diseases. As a major player in pharmaceutical innovation, the company integrates industry expertise with a strategic focus on anti-infective solutions, ensuring its technology remains both disruptive and adaptive within an evolving market landscape.

Advanced Technology and Drug Delivery

Central to Matinas Biopharm's operations is its proprietary nanotechnology, which employs lipid-crystal nanoparticle cochleates to nano-encapsulate drugs. This process enhances the safety profile and tolerability of traditional drug compounds by reducing toxicity and improving oral bioavailability. The use of this disruptive technology not only streamlines drug development but also opens up new therapeutic avenues for patients in need of effective treatment for fungal and bacterial infections. The description of these processes reflects an in-depth understanding of nano-encapsulation and its critical role in modern drug delivery systems.

Innovative Pipeline and Clinical Focus

Matinas Biopharm has built a pipeline centered on anti-infective candidates that employ its unique encochleation technology. MAT2203, the lead candidate, is an orally administered formulation of amphotericin B, a broad spectrum fungicidal agent, positioned to potentially replace more invasive administration methods. In parallel, MAT2501 represents an encochleated formulation of amikacin, designed to combat acute bacterial infections, including non-tuberculous mycobacterium and multidrug-resistant gram-negative infections. The company’s focus on these specific clinical stages underscores its commitment to addressing areas of high unmet medical need and harnessing its expertise in reformulating established therapeutic agents for enhanced patient outcomes.

Industry Dynamics and Competitive Landscape

Operating within the competitive milieu of clinical-stage biopharmaceutical research, Matinas Biopharm distinguishes itself through its edge in advanced drug delivery solutions. Its technology not only redefines the administration of established pharmaceuticals but also presents a more patient-friendly alternative to traditional IV therapies. This strategic approach allows the company to secure a niche in the broader market, by addressing the limitations of conventional treatment modalities. The company continuously evaluates its clinical strategies within a framework that balances innovative potential with rigorous regulatory pathways, ensuring that every step is buttressed by solid scientific rationale and deep industry insight.

Market Significance and Operational Insights

Matinas Biopharm’s operational model is founded on a commitment to enhancing existing treatment landscapes. By focusing on orphan indications and leveraging a technology that minimizes the adverse effects associated with standard drug formulations, the company targets a market segment that requires both innovation and reliability. Its strategic emphasis on the reformulation of drugs into more patient-centric, orally available therapies marks a pivotal shift in the way anti-infective treatments are developed and administered. This not only repositions current therapeutic paradigms but also lays a robust groundwork for clinical research advancements, aligning with global trends in biopharmaceutical innovations.

Throughout its journey, Matinas Biopharm has adhered strictly to principles of scientific rigor and operational transparency. The organization’s methodical approach to drug development, combined with its commitment to leveraging novel technologies, makes it a pivotal subject for investors and analysts aiming to understand emerging trends in the anti-infective space. The holistic view offered here integrates multiple facets of the company—from technological breakthroughs and pipeline progress to broader industry trends—presenting a well-rounded perspective designed to inform and educate stakeholders comprehensively.

Rhea-AI Summary
Matinas BioPharma (MTNB) provides a positive update on its Compassionate/Expanded Use Access Program with MAT2203, showing promising results in treating invasive fungal infections. Out of 19 patients enrolled, those completing treatment had complete clinical resolution, with significant improvements seen in others. MAT2203 demonstrated efficacy in patients with limited treatment options, addressing a significant medical need.
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Matinas BioPharma announces alignment with the FDA on the design of a Phase 3 trial for MAT2203 in patients with invasive aspergillosis. The trial aims to provide a step-down treatment option for adults with limited or no treatment choices, focusing on all-cause mortality and treatment-related toxicities.
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Matinas BioPharma (NYSE American: MTNB) announces CEO Jerome D. Jabbour will present a company overview at the Biotech Showcase 2024. The presentation will be available via webcast on the company's website. Institutional investors can schedule meetings with management.
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Matinas BioPharma Holdings, a clinical-stage biopharmaceutical company (NYSE American: MTNB), reports successful oral delivery of LNC-formulated small single-strand oligonucleotides targeting key inflammatory cytokines TNFα and IL-17A in acute colitis and psoriasis models, showing significant reductions in serum TNFα levels and tissue IL-17A mRNA, with improvements in clinical disease markers.
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Matinas BioPharma Holdings, Inc. (NYSE American: MTNB) receives positive feedback from FDA on Phase 3 study design for MAT2203, moving closer to full alignment with FDA. Partnership discussions ongoing. Meeting with FDA planned in early 2024 to finalize Phase 3 protocol.
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MTNB: Matinas BioPharma reports positive FDA feedback on MAT2203 Phase 3 program for invasive aspergillosis, acknowledging LPAD pathway potential. Oral LNC formulation of docetaxel shows comparable tumor reduction to IV-docetaxel in preclinical model.
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Matinas BioPharma Holdings, Inc. announces positive results from an in vivo animal study of an oral LNC formulation of docetaxel, showing reductions in tumor size comparable to IV docetaxel and no systemic toxicity.
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Matinas BioPharma Holdings, Inc. (NYSE American: MTNB) will report its third quarter 2023 financial results after market close on November 8, 2023. The company will host an investment community conference call and webcast at 4:30 p.m. Eastern time to discuss the results and provide a business update. Dial-in information is available for the call and the webcast will be archived on the company's website.
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Matinas BioPharma announces complete clinical resolution of patient's recurrent hemorrhagic cystitis with MAT2203
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Matinas BioPharma to present at investment conferences on October 12 and October 19, 2023
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FAQ

What is the current stock price of Matinas Biopharm (MTNB)?

The current stock price of Matinas Biopharm (MTNB) is $0.5999 as of April 22, 2025.

What is the market cap of Matinas Biopharm (MTNB)?

The market cap of Matinas Biopharm (MTNB) is approximately 3.0M.

What is the core focus of Matinas Biopharm?

Matinas Biopharm is focused on developing innovative anti-infectives for orphan indications through advanced drug reformulation techniques.

What technology does Matinas Biopharm use in its drug development?

The company utilizes lipid-crystal nanoparticle cochleate technology to nano-encapsulate existing drugs, enhancing safety, tolerability, and oral bioavailability.

What are the main candidates in Matinas Biopharm's pipeline?

The pipeline includes MAT2203, an encochleated formulation of amphotericin B for fungal infections, and MAT2501, an encochleated formulation of amikacin targeting bacterial infections.

How does Matinas Biopharm differentiate its products from traditional formulations?

By reformulating drugs into orally bioavailable forms, the company reduces toxicity and improves patient tolerability compared to traditional intravenous methods.

Which infections are targeted by Matinas Biopharm's lead candidates?

The lead candidates target a range of infections, including fungal infections with MAT2203 and both non-tuberculous mycobacterial and multidrug-resistant gram-negative bacterial infections with MAT2501.

In what clinical phases are the lead candidates currently?

MAT2203 is in an advanced clinical phase while MAT2501 is in early clinical development, reflecting a diversified approach within the anti-infective space.

How does Matinas Biopharm's technology impact the current anti-infective treatment landscape?

The innovative encochleation process enhances the delivery of medications by making them safer and more accessible via oral administration, addressing key limitations of traditional treatments.
Matinas Biopharm

NYSE:MTNB

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Biotechnology
Pharmaceutical Preparations
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