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Medicenna Therapeutics Corp - MDNA STOCK NEWS

Welcome to our dedicated page for Medicenna Therapeutics news (Ticker: MDNA), a resource for investors and traders seeking the latest updates and insights on Medicenna Therapeutics stock.

Medicenna Therapeutics (MDNA) is a clinical-stage immunotherapy company at the forefront of developing novel and highly selective versions of IL-2, IL-4, and IL-13 superkines and first-in-class Empowered Cytokines (ECs). With a mission to lead in the development and commercialization of targeted ECs and superkines, Medicenna aims to revolutionize treatment for a broad range of cancers and immune-mediated diseases. The company leverages its expertise and collaborates with world-class researchers to create unique superkines.

Medicenna's innovative approach allows these superkines to function either as standalone short or long-acting therapeutics or to be fused with pro-apoptotic proteins. This fusion precisely delivers potent cell-killing agents to cancer cells, the immunosuppressive tumor micro-environment, and cancer stem cells, sparing healthy cells from harm. Additionally, these superkines can be fused with antibodies to create novel 'immunocytokines' or combined with other treatment modalities.

Currently, Medicenna is engaged in various promising projects. A notable recent achievement includes the characterization of its tumor-targeting and activatable T-MASK platform, designed to enhance tumor accumulation and tolerability of potent immune modulators. This innovation was presented at a significant conference on November 3, 2023.

As Medicenna continues to advance its pipeline of targeted treatments, it remains committed to transforming the therapeutic landscape for cancer and immune-related conditions. The company's financial health is supported by strategic partnerships and a focus on groundbreaking research and development.

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On September 21, 2022, Medicenna Therapeutics Corp. (NASDAQ: MDNA) held its annual shareholder meeting, announcing that all management nominees for the Board of Directors were elected with over 97% of votes in favor. Notable nominees include Dr. Fahar Merchant and Mr. Albert Beraldo. The meeting also confirmed PricewaterhouseCoopers LLP as the Company's auditor. A total of 57.468% of common shares were represented in the vote, reflecting strong shareholder engagement.

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Medicenna Therapeutics Corp. (NASDAQ: MDNA; TSX: MDNA) has partnered with Merck to explore the combination of MDNA11, a long-acting IL-2 Superkine, with Merck’s KEYTRUDA for treating advanced solid tumors. This collaboration involves the ABILITY Study which will assess the safety and efficacy of MDNA11 alone and alongside KEYTRUDA. Medicenna will sponsor the study while Merck provides the drug. CEO Fahar Merchant emphasized the potential of this collaboration to enhance therapeutic outcomes.

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Medicenna Therapeutics Corp. (NASDAQ: MDNA, TSX: MDNA) will present at several conferences in September 2022. At the H.C. Wainwright 24th Annual Global Investment Conference, an on-demand corporate presentation will be available on September 12. Medicenna will also feature an oral presentation on IL-2 programs at The Promise of Interlukin-2 Therapy Conference in Paris on September 17. Additionally, findings from its preclinical Superkine programs will be presented at the Cytokines 2022 meeting in Hawaii from September 20-23. Poster presentations will occur on September 20.

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Medicenna Therapeutics reported a solid start to fiscal 2023, bolstered by a US$20 million raise extending its cash runway into 2024. The ABILITY study of MDNA11 shows tumor control in 4 of 10 patients with advanced solid tumors, including an unconfirmed partial response in a pancreatic cancer patient. The company has no reported dose-limiting toxicities and is progressing into the fifth cohort of the clinical trial. Financially, a net loss of CAD 4.2 million was noted, a decrease from CAD 6.4 million in 2021. The results reflect reduced R&D spending as the company advances its innovative pipeline.

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Medicenna Therapeutics Corp. (NASDAQ: MDNA, TSX: MDNA) has successfully closed its marketed underwritten public offering of units at a price of US$1.50 per unit, raising approximately US$20 million in gross proceeds. A total of 13,333,334 units were issued, each comprising one common share and one warrant, which allows purchase of additional shares at US$1.85 over the next 60 months. The funds will primarily support the clinical development of MDNA11 and general corporate purposes. The offering was conducted under an underwriting agreement with Guggenheim Securities and Bloom Burton Securities.

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Medicenna Therapeutics Corp. (NASDAQ: MDNA) announced a priced public offering of 13,333,334 units at $1.50 each, aiming to raise approximately $20 million. Each unit consists of one common share and one warrant, allowing purchase of an additional share at $1.85 within five years. The offering is set to close around August 11, 2022, pending customary conditions. Proceeds will primarily fund clinical development of MDNA11 and preclinical efforts for a BiSKIT candidate.

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Medicenna Therapeutics Corp. (Nasdaq: MDNA, TSX: MDNA) announced a marketed underwritten public offering of units, each consisting of one common share and one warrant. The offering's pricing will be determined in the market context, and completion is not guaranteed. Funds raised will primarily support the clinical development of MDNA11 and a BiSKIT candidate. Guggenheim Securities is the sole book-running manager for the offering. A preliminary prospectus supplement has been filed, with the final documents outlining the offering details to be available shortly.

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Medicenna Therapeutics Corp. (NASDAQ: MDNA, TSX: MDNA) announced a conference call on August 15, 2022, at 8:30 AM ET to present its Q1 fiscal 2023 financial results and operational highlights. Investors can join the call by dialing 1-877-407-9716 (Canada/US) or 1-201-493-6779 (international) with conference ID 13731985. A live webcast will also be available on their website, along with an archived version post-event. Medicenna focuses on developing innovative immunotherapy treatments, specifically Superkines targeting IL-2, IL-4, and IL-13.

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Medicenna Therapeutics announced promising results from the Phase 1/2 ABILITY study of its IL-2 super agonist, MDNA11. Tumor control was achieved in 40% of evaluable patients, including those with hard-to-treat cancers like sarcomas and pancreatic cancer. The study's fifth dose-escalation cohort is now enrolling after a favorable safety review. Notably, treatment did not result in dose-limiting toxicities. The data will be presented at the Cytokine Based Drug Development Summit, further supporting MDNA11’s potential as a leading IL-2 therapeutic.

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Medicenna Therapeutics Corp. (NASDAQ: MDNA) reported its financial results for the fiscal year ending March 31, 2022, highlighting significant clinical progress with its MDNA11 program, where tumor control was observed in 3 of 8 patients in early dosing cohorts. The company extended its cash runway into Q2 2023, holding $20.5 million in cash and equivalents. Despite a net loss of $22.6 million due to increased R&D expenditures, management remains optimistic about upcoming milestones, including initial clinical data expected in mid-2022.

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FAQ

What does Medicenna Therapeutics specialize in?

Medicenna Therapeutics specializes in developing novel and highly selective versions of IL-2, IL-4, and IL-13 superkines and first-in-class Empowered Cytokines (ECs) for treating cancer and immune-mediated diseases.

What are superkines?

Superkines are engineered cytokines with enhanced properties. They can be used as short or long-acting therapeutics or fused with other proteins to deliver targeted treatments to cancer cells and the tumor micro-environment.

How does Medicenna's T-MASK platform work?

The T-MASK platform is a tumor-targeting and activatable system designed to improve the accumulation and tolerability of potent immune modulators in tumors, sparing healthy tissues.

What are empowered cytokines (ECs)?

Empowered Cytokines (ECs) are enhanced versions of natural cytokines that have been genetically engineered to improve their therapeutic effects and target cancer cells more effectively.

What recent achievements has Medicenna made?

A recent achievement includes the presentation of their T-MASK platform, which enhances tumor accumulation and tolerability of immune modulators, at a major conference on November 3, 2023.

What is the company's mission?

Medicenna's mission is to lead in the development and commercialization of targeted ECs and superkines to treat a broad range of cancers and immune-mediated diseases.

How does Medicenna ensure the safety of its treatments?

Medicenna's treatments are designed to precisely target cancer cells and the tumor micro-environment without harming healthy cells, ensuring a safer therapeutic approach.

What are immunocytokines?

Immunocytokines are cytokines fused with antibodies, combining the properties of both to improve targeting and efficacy in cancer treatment.

How does Medicenna collaborate with other researchers?

Medicenna collaborates with world-class researchers to harness cutting-edge science and expertise, driving innovation in their therapeutic developments.

What is the financial outlook for Medicenna?

Medicenna's financial health is bolstered by strategic partnerships, ongoing research and development, and a pipeline of promising therapeutic candidates.

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