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MDB Capital Collaborates with Mayo Clinic to Advance Anti-Senescence Platform

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MDB Capital Holdings (NASDAQ: MDBH) has announced a collaboration with Mayo Clinic to develop a small molecule anti-senescence platform. This partnership targets research in longevity and the prevention of age-related diseases by eliminating senescent cells, which are linked to chronic low-grade inflammation and various age-related diseases, including fibrosis. Mayo Clinic's studies have demonstrated the potential of the molecule to significantly reverse fibrosis. The global market for longevity and anti-senescence therapy is projected to reach $45 billion by 2030. Both MDB's CEO, Christopher Marlett, and Mayo Clinic's Dr. Andrew J. Haak expressed enthusiasm about the collaboration's potential to advance patient care.

Positive
  • MDB Capital Holdings' collaboration with Mayo Clinic on an anti-senescence platform could open significant market opportunities, with the longevity and anti-senescence therapy market projected to reach $45 billion by 2030.
  • Mayo Clinic's studies indicate that the licensed molecule has a significant therapeutic window to target and eliminate senescent cells, potentially reversing fibrosis across multiple conditions.
Negative
  • Mayo Clinic's financial interest in the technology may create conflicts of interest, potentially affecting the impartiality and commercialization of the results.

Insights

MDB Capital's collaboration with Mayo Clinic is a significant step in the longevity and anti-senescence therapy market, projected to hit 45 billion by 2030. This partnership leverages Mayo Clinic's extensive research capabilities and MDB's venture platform to advance a small molecule anti-senescence platform. Senescent cells are dysfunctional cells that stop dividing and contribute to aging and chronic inflammation, leading to various age-related diseases, including fibrosis.

Eliminating these cells could open up new treatments for diseases with limited options. By focusing on reversing fibrosis, MDB positions itself at the forefront of innovative therapies that could address prevalent medical conditions with high unmet needs. Beyond the potential health benefits, this collaboration could bolster MDB's reputation in the biotech sector, attracting further investments and partnerships.

For retail investors, understanding the potential of anti-senescence therapies is crucial. These treatments are not just about extending life but improving the quality of life in aging populations, which is a rapidly growing demographic. However, the development and approval process for new therapies can be long and uncertain. Therefore, while the collaboration is promising, it requires a long-term investment perspective.

The anti-senescence market's growth trajectory is significant, with projections nearing 45 billion by 2030. MDB's collaboration with Mayo Clinic strategically positions the company in a rapidly expanding sector. This partnership not only enhances MDB's portfolio but also taps into Mayo Clinic's established medical research credibility.

Retail investors should note that while the anti-senescence market holds substantial potential, it is also highly competitive with numerous players aiming to capitalize on the aging population trend. MDB's unique angle, backed by Mayo Clinic's research, could provide a competitive edge. However, investors should remain cautious about the long timeline typically associated with biotech developments and regulatory approvals.

In essence, this collaboration could significantly enhance MDB's market position and potentially lead to substantial financial returns. But patience and a long-term investment horizon are advisable, considering the nature of the industry.

ADDISON, Texas, July 08, 2024 (GLOBE NEWSWIRE) -- MDB Capital Holdings, LLC, (NASDAQ: MDBH) (“MDB”), a public venture platform focused on launching category-leading deep technology companies, today announced a collaboration through a patent and know-how agreement with Mayo Clinic to develop a small molecule anti-senescence platform. This collaboration aims to advance research in longevity and age-related disease prevention.

Senescent cells, which are dysfunctional cells that have permanently stopped dividing, have been implicated in the aging process and the development of chronic low-grade inflammation. This chronic inflammation has been linked to a variety of age-related diseases, including multiple fibrotic conditions that have limited treatment options and poor prognoses.

Studies conducted at Mayo Clinic have shown the potential of the licensed molecule to target and eliminate senescent cells with a significant therapeutic window, reversing fibrosis across multiple conditions. The global longevity and anti-senescence therapy market is projected to reach nearly $45 billion by 2030.

"We're thrilled to collaborate with Mayo Clinic to harness clinical and scientific expertise to develop therapeutics that could meaningfully improve patient lives across various conditions,” said Christopher Marlett, CEO and Co-Founder of MDB.

"Our team is deeply invested in addressing the underlying drivers of aging and fibrotic conditions, which is why we are so excited about this new collaborative effort,” said Dr. Andrew J. Haak, PhD, Assistant Professor and Researcher at Mayo Clinic.

Mayo Clinic has a financial interest in the technology referenced in this press release. Mayo Clinic will use any revenue it receives to support its not-for-profit mission in patient care, education and research.

About MDB Capital Holdings, LLC

Founded in 1997, MDB Capital focuses on launching “Big Ideas” into valuable public companies with a better approach to public venture capital. This approach involves community-driven financings of pre-revenue, early-stage deep technology companies through early public offerings, primarily listed on NASDAQ, as well as post-IPO offerings for already public companies that fit MDB’s overall criteria for investment.

MDB Capital is the brand under which MDB Capital Holdings, LLC (NASDAQ: MDBH) and its subsidiaries operate and provide services, which includes a self-clearing broker-dealer and trading platform and an integrated, intellectual property (IP) strategy consulting and law firm.

MDB Capital (a dba of Public Ventures, LLC) is a registered broker-dealer, Member FINRA/SIPC.

For more information, please visit www.mdb.com.

Forward-Looking Statements

This press release contains "forward-looking statements." These forward-looking statements are made as of the date they were first issued and were based on current expectations, estimates, forecasts and projections as well as the beliefs and assumptions of management. Words such as "expect," "anticipate," "should," "believe," "hope," "target," "project," "goals," "estimate," "potential," "predict," "may," "will," "might," "could," "intend," "shall" and variations of these terms or the negative of these terms and similar expressions are intended to identify these forward-looking statements.

Forward-looking statements are subject to a number of risks and uncertainties, many of which involve factors or circumstances that are beyond MDB's control. MDB's actual results could differ materially from those stated or implied in forward-looking statements due to a number of factors, including but not limited to, risks detailed in documents that may be filed by MDB from time to time with the SEC. The forward-looking statements included in this press release represent MDB's views as of the date of this press release. MDB anticipates that subsequent events and developments will cause its views to change. MDB undertakes no intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise. These forward-looking statements should not be relied upon as representing MDB's views as of any date subsequent to the date of this press release.

Investor Relations Contact:
IR@mdb.com

Media Contact:
press@mdb.com

SOURCE: MDB Capital Holdings, LLC


FAQ

What is MDB Capital Holdings' stock symbol?

MDB Capital Holdings is listed under the stock symbol MDBH.

What is the focus of MDB Capital Holdings' recent collaboration with Mayo Clinic?

MDB Capital Holdings is collaborating with Mayo Clinic to develop a small molecule anti-senescence platform aimed at advancing research in longevity and the prevention of age-related diseases.

What market potential does the anti-senescence platform collaboration between MDB Capital Holdings and Mayo Clinic have?

The global market for longevity and anti-senescence therapy is projected to reach nearly $45 billion by 2030.

What are senescent cells, and why are they significant in the MDB Capital Holdings and Mayo Clinic collaboration?

Senescent cells are dysfunctional cells that have stopped dividing and are linked to chronic inflammation and various age-related diseases, including fibrosis. The collaboration aims to eliminate these cells to improve health outcomes.

What is the potential impact of the licensed molecule studied by Mayo Clinic?

Studies at Mayo Clinic show that the licensed molecule can significantly reverse fibrosis by targeting and eliminating senescent cells.

Why is Mayo Clinic's financial interest in the MDB Capital Holdings collaboration noteworthy?

Mayo Clinic's financial interest in the technology may affect the impartiality and commercialization of the collaboration's results.

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