Welcome to our dedicated page for Lexicon Pharmaceuticals news (Ticker: LXRX), a resource for investors and traders seeking the latest updates and insights on Lexicon Pharmaceuticals stock.
Lexicon Pharmaceuticals, Inc. (NASDAQ: LXRX) is a biopharmaceutical company whose news flow centers on cardiometabolic and neurological drug development, regulatory interactions and strategic collaborations. The company describes a mission of pioneering medicines that transform patients’ lives, supported by its Genome5000™ genomics platform, which identified more than 100 protein targets with therapeutic potential across multiple diseases.
News about Lexicon frequently highlights clinical data and conference presentations for sotagliflozin, an oral SGLT2 and SGLT1 inhibitor studied in approximately 20,000 patients with heart failure, diabetes and chronic kidney disease. Recent updates include results in heart failure with preserved ejection fraction, ongoing enrollment in the SONATA-HCM Phase 3 study for hypertrophic cardiomyopathy, and work toward regulatory pathways for ZYNQUISTA® in type 1 diabetes.
Investors and healthcare observers can also follow developments in pilavapadin (LX9211) for diabetic peripheral neuropathic pain, where Lexicon has reported Phase 2 and Phase 2b data and End-of-Phase 2 FDA discussions, as well as LX9851, a first-in-class ACSL5 inhibitor for obesity and cardiometabolic disorders licensed to Novo Nordisk. Company news includes licensing milestones, financial results, participation in major healthcare conferences and policy-focused initiatives such as a chronic pain roundtable and white paper on non-opioid treatments.
This LXRX news page aggregates these updates in one place, covering earnings releases, pipeline milestones, regulatory announcements, scientific publications and partnership news drawn from Lexicon’s public statements and SEC filings.
Lexicon Pharmaceuticals announced a new post-hoc analysis of pooled Phase 3 data showing that INPEFA® (sotagliflozin), a dual oral inhibitor of SGLT2 and SGLT1, significantly reduced the risk of heart failure events in patients with preserved ejection fraction (HFpEF). The analysis, presented at the Heart Failure Association of the European Society of Cardiology Congress, highlighted INPEFA's effectiveness in patients with obesity-related HFpEF. Data from the SOLOIST-WHF and SCORED trials involving 1,932 patients indicated that age, sex, and BMI were important risk factors. Notably, older patients and those with higher BMI saw a greater reduction in primary endpoint events with INPEFA compared to placebo. The findings emphasize the need for personalized treatment strategies for HFpEF patients.
Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) will participate in the Bank of America Securities Healthcare Conference 2024. Jeff Wade, Lexicon’s president and chief financial officer, will present on May 14, 2024. A webcast will be available on the Lexicon website.
Lexicon Pharmaceuticals reported financial results for the first quarter of 2024, highlighting the progress in the commercial launch of INPEFA for heart failure. They also provided updates on the resubmission of NDA for ZYNQUISTA in Type 1 Diabetes, Phase 3 study of sotagliflozin in Hypertrophic Cardiomyopathy, and Phase 2b PROGRESS study of LX9211 in Diabetic Peripheral Neuropathic Pain. The company remains focused on advancing its pipeline with the selection of LX9851 for obesity and weight management. Financially, the company reported revenues of $1.1 million, with increased R&D and SG&A expenses resulting in a net loss of $48.4 million for the quarter. Lexicon Pharmaceuticals remains well-capitalized with $355.6 million in cash and investments.
Lexicon Pharmaceuticals, Inc. announced the retirement of Lonnel Coats as CEO and board member effective July 7, 2024. The board is searching for a new CEO. Under Coats' leadership, Lexicon has advanced compounds through development, transformed into a biopharmaceutical business, and built a strong management team. Coats expressed gratitude for the opportunity to lead the company and highlighted upcoming initiatives, including the launch of new products and clinical studies.
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