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Lexeo Therapeutics, Inc. - LXEO STOCK NEWS

Welcome to our dedicated page for Lexeo Therapeutics news (Ticker: LXEO), a resource for investors and traders seeking the latest updates and insights on Lexeo Therapeutics stock.

Lexeo Therapeutics, Inc. (Nasdaq: LXEO) is a clinical-stage genetic medicines company focused on developing innovative gene therapies for genetically defined cardiovascular diseases and APOE4-associated Alzheimer's disease. The company's primary aim is to transform healthcare by leveraging pioneering science and delivering one-time treatments for conditions with significant unmet medical needs.

Lexeo's pipeline includes several promising gene therapy candidates at various stages of development. For instance, LX2020 is an AAVrh10-based gene therapy designed to treat PKP2-ACM, a genetic cardiovascular disorder with no current approved treatments. The compound has received Orphan Drug and Fast Track designations from the FDA, highlighting its potential to address a serious and life-threatening disease. The planned Phase 1/2 trial, HEROIC-PKP2, aims to evaluate the safety and efficacy of LX2020 in adult patients.

Another key candidate is LX2006, an AAV-based gene therapy for FA cardiomyopathy, a leading cause of death among Friedreich ataxia (FA) patients. LX2006 has also garnered Orphan Drug, Rare Pediatric Disease, and Fast Track designations from the FDA. The ongoing SUNRISE-FA trial is assessing the safety and preliminary efficacy of LX2006, with long-term data collection planned for five years post-treatment.

Recent developments have seen Lexeo securing significant investments through a private placement, extending its financial runway into 2027. This financing round was co-led by Braidwell LP and Adage Capital Partners LP, with participation from other notable investors such as RA Capital Management and Novo Holdings A/S. The funds will be utilized to advance ongoing clinical stage programs and support general corporate purposes.

Additionally, Lexeo has entered into an in-license agreement with Cornell University to expedite the development of LX2006 for FA cardiomyopathy. This agreement provides Lexeo with access to current and future data from an ongoing Phase 1A trial, potentially accelerating regulatory engagements and enhancing the overall data package for LX2006.

Under the leadership of CEO R. Nolan Townsend, Lexeo Therapeutics is committed to advancing its pipeline through rigorous clinical evaluations, aiming to deliver transformative therapies for patients suffering from severe genetic disorders. The company's New York City headquarters serve as a hub for its innovative research and development activities.

Rhea-AI Summary

Lexeo Therapeutics reported strong financial results for the first quarter of 2024, closing an oversubscribed $95 million equity financing in March, with a cash balance of $195.1 million. The company is dedicated to developing treatments for genetically defined cardiovascular diseases and APOE4-associated Alzheimer's disease. Lexeo completed an in-license agreement with Cornell University for intellectual property rights related to ongoing clinical trials, with anticipated milestones for multiple gene therapy candidates in 2024.

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Lexeo Therapeutics, Inc. (Nasdaq: LXEO) will participate in upcoming investor conferences to discuss their innovative treatments for cardiovascular diseases and Alzheimer's disease. The company's management will engage in fireside chats at various events, providing investors with valuable insights into their genetic medicine advancements.

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Lexeo Therapeutics announced a license agreement with Cornell University to expedite the development of gene therapy candidate LX2006 for Friedreich ataxia cardiomyopathy. Lexeo gains intellectual property rights, including current and future clinical data, to support regulatory discussions. The combined data from ongoing trials is expected to be released in mid-2024.
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Lexeo Therapeutics receives FDA Fast Track designation for LX2006, a gene therapy candidate for Friedreich’s Ataxia Cardiomyopathy.
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Lexeo Therapeutics, Inc. extends its financial runway until 2027 through a private placement led by Braidwell LP and Adage Capital Partners LP, raising approximately $95.0 million. The company sold 6,278,905 shares of its common stock at $15.13 per share. The funds will support ongoing clinical programs, working capital, and general corporate purposes, ensuring financial stability for the next few years.
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Lexeo Therapeutics announces $95.0M equity financing, positive frataxin protein expression data in SUNRISE-FA trial, and operational highlights for 2023.
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Lexeo Therapeutics, Inc. (Nasdaq: LXEO) extends its financial runway into 2027 through a private placement, raising approximately $95.0 million. The company entered into a common stock purchase agreement with institutional and healthcare accredited investors, issuing 6,278,905 shares of Common Stock at $15.13 per share. The financing, co-led by Braidwell LP and Adage Capital Partners LP, includes participation from RA Capital Management, Surveyor Capital, Eventide Asset Management, and Novo Holdings A/S. J.P. Morgan and Leerink Partners served as co-lead placement agents. The proceeds will fund ongoing clinical programs and general corporate purposes, ensuring financial stability until 2027.
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Lexeo Therapeutics, Inc. (Nasdaq: LXEO) announced new executive appointments to lead the company’s pipeline into late-stage clinical development. The appointments include: Sandi See Tai, MD, as Chief Development Officer, Eric Adler, MD, as Chief Medical Officer & Head of Research, Rajiv Patni, MD, as Senior Advisor to the CEO and Board of Directors, and Jenny R. Robertson as Chief Business and Legal Officer.
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Lexeo Therapeutics, Inc. (Nasdaq: LXEO) to present at 42nd Annual J.P. Morgan Healthcare Conference on January 10, 2024, focusing on genetic medicine treatments for cardiovascular diseases and APOE4-associated Alzheimer's disease.
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Lexeo Therapeutics, Inc. (Nasdaq: LXEO) has received Fast Track and Orphan Drug designations from the FDA for its gene therapy candidate LX2020, aimed at treating arrhythmogenic cardiomyopathy (ACM) caused by mutations in the PKP2 gene. The company plans to conduct a Phase 1/2 trial, HEROIC-PKP2, to determine the safety and efficacy of LX2020 in adult patients with PKP2-ACM, with potential long-term safety and efficacy evaluation for an additional four years following completion of the initial trial.
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FAQ

What is the current stock price of Lexeo Therapeutics (LXEO)?

The current stock price of Lexeo Therapeutics (LXEO) is $6.28 as of December 20, 2024.

What is the market cap of Lexeo Therapeutics (LXEO)?

The market cap of Lexeo Therapeutics (LXEO) is approximately 197.1M.

What is Lexeo Therapeutics, Inc. known for?

Lexeo Therapeutics, Inc. is known for its development of gene therapies targeting genetically defined cardiovascular diseases and APOE4-associated Alzheimer's disease.

What are some of Lexeo's key products in development?

Key products include LX2020 for PKP2-ACM and LX2006 for FA cardiomyopathy, both of which have received FDA designations highlighting their potential.

What recent achievements has Lexeo Therapeutics made?

Lexeo has received Orphan Drug and Fast Track designations for LX2020, and secured significant investment to extend its financial runway into 2027.

What does the Orphan Drug designation mean for Lexeo?

The Orphan Drug designation provides benefits such as market exclusivity upon regulatory approval, exemption of FDA application fees, and tax credits for clinical trials.

How is Lexeo advancing the development of LX2006?

Lexeo has entered into an in-license agreement with Cornell University, acquiring rights to current and future data from ongoing trials to expedite the development of LX2006.

What is the purpose of the Phase 1/2 HEROIC-PKP2 trial?

The HEROIC-PKP2 trial aims to determine the safety and tolerability of LX2020 in adult patients with PKP2-ACM and assess preliminary efficacy measures.

Who are the notable investors in Lexeo's recent financing round?

The recent private placement was co-led by Braidwell LP and Adage Capital Partners LP, with participation from RA Capital Management, Novo Holdings A/S, and others.

What is the significance of the Fast Track designation for LX2006?

The Fast Track designation allows for more frequent FDA interactions to facilitate development and expedite the review process for treatments addressing serious conditions.

What are the long-term goals for Lexeo Therapeutics?

Lexeo aims to transform healthcare by applying pioneering science to develop one-time gene therapies that address high unmet medical needs in genetic diseases.

Where is Lexeo Therapeutics headquartered?

Lexeo Therapeutics is headquartered in New York City.

Lexeo Therapeutics, Inc.

Nasdaq:LXEO

LXEO Rankings

LXEO Stock Data

197.14M
31.50M
0.49%
91.48%
6.64%
Biotechnology
Biological Products, (no Disgnostic Substances)
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United States of America
NEW YORK