Lantern Pharma Inc. develops AI-driven precision oncology therapies and research platforms for cancer drug discovery. The company uses its proprietary RADR® platform to identify and advance small-molecule oncology candidates, including LP-300, LP-184 and LP-284, and develops STAR-001 for CNS cancers through Starlight Therapeutics, its wholly owned subsidiary.
Recurring news includes clinical-program updates for lung cancer, hematologic cancers, sarcomas and brain cancers; FDA and trial-design communications; financial results; and commercialization of AI tools such as withZeta.ai and predictBBB.ai. Company updates also cover subscription-based platform access, computational biology features and enterprise deployment for biomedical research and drug-development users.
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Lantern Pharma (NASDAQ: LTRN) announced the U.S. Patent and Trademark Office has issued a notice of allowance for its patent application related to its drug candidate LP-284, targeting non-Hodgkin's lymphomas. This patent is expected to provide market exclusivity until 2039. The company plans to submit an Investigational New Drug (IND) application for LP-284 to the FDA in mid-2023 and commence a Phase 1 clinical trial later this year. LP-284, with nanomolar potency, addresses significant unmet needs among patients with mantle cell lymphoma (MCL) and double-hit lymphoma (DHL), presenting an estimated annual market potential of $1.2 billion. The candidate has also received Orphan Drug Designation from the FDA for MCL, enhancing its development pathway.
Lantern Pharma Inc. (NASDAQ: LTRN) has initiated the Phase 2 Harmonic™ clinical trial, dosing the first patient with its investigational drug LP-300 in combination with chemotherapy for never smokers with advanced non-small cell lung cancer (NSCLC). The trial aims to assess the overall and progression-free survival in 90 patients, with 60 receiving LP-300 and 30 on standard chemotherapy. Previous trials showed a 91% overall survival rate at two years for LP-300 patients compared to those on chemotherapy alone. The market potential for this demographic is estimated between $1.5 to $2.0 billion.
Lantern Pharma Inc. (NASDAQ: LTRN), a biopharmaceutical company utilizing its RADR® AI platform for oncology drug development, announced presentations at three upcoming events. CEO Panna Sharma will present on March 22 at the Rare Disease Innovation & Partnership Summit in Philadelphia, discussing AI in drug development. He will also participate in a free webinar on March 23, co-hosted by Science History Institute and American Chemical Society, focusing on AI's impact on drug discovery. Additionally, Peter Carr will moderate a session at the Genomics in Precision Oncology Xchange on April 5 in Boston, emphasizing clinical trial design.
For more information, visit www.lanternpharma.com.