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About Lexaria Bioscience Corp.
Lexaria Bioscience Corp. (NASDAQ:LEXX, NASDAQ:LEXXW) is a global innovator in drug delivery technology, specializing in its patented DehydraTECH™ platform. This groundbreaking technology enhances the way active pharmaceutical ingredients (APIs) are absorbed into the bloodstream, offering faster onset times, improved bioavailability, and reduced side effects. DehydraTECH is applicable across a wide range of APIs, including cannabinoids, antiviral drugs, nicotine, and GLP-1 receptor agonists, making it a versatile solution in the pharmaceutical and biotechnology industries.
Core Technology: DehydraTECH™
DehydraTECH™ is a patented drug delivery formulation and processing platform that optimizes the oral delivery of APIs. By improving bio-absorption rates—up to 27 times higher for cannabinoids in some cases—and reducing onset times from hours to minutes, the technology addresses critical challenges in drug delivery. It has also demonstrated the ability to facilitate the transport of APIs across the blood-brain barrier, a significant advantage for treating neurological conditions.
Market Applications
Lexaria’s technology is particularly impactful in high-growth markets:
- GLP-1 Drugs: DehydraTECH has shown promise in enhancing the oral delivery of GLP-1 receptor agonists like semaglutide, liraglutide, and tirzepatide, which are used to treat diabetes, obesity, and cardiovascular diseases. By enabling oral formulations, Lexaria aims to replace the widely disliked injectable versions of these drugs.
- Neurological Disorders: The technology's ability to cross the blood-brain barrier positions it as a valuable tool in treating conditions like epilepsy and Alzheimer’s disease.
- Cannabinoids: DehydraTECH optimizes the delivery of cannabinoids for therapeutic applications, including pain management and seizure mitigation.
Business Model and Revenue Streams
Lexaria operates through four primary segments:
- Intellectual Property Licensing: The company licenses its technology to pharmaceutical and nutraceutical companies, generating recurring revenue.
- B2B Production: Lexaria produces DehydraTECH-enhanced formulations for business partners.
- Research and Development: The company conducts extensive R&D to expand its technology’s applications and validate its efficacy.
- Corporate Operations: This includes strategic planning and partnerships to drive growth.
Competitive Landscape
In the GLP-1 drug market, Lexaria competes with pharmaceutical giants like Novo Nordisk and Eli Lilly. However, its ability to deliver APIs effectively through oral formulations offers a distinct competitive edge. The company’s focus on reducing gastrointestinal side effects and improving patient compliance further strengthens its market position.
Intellectual Property
Lexaria boasts a robust intellectual property portfolio with 48 granted patents and numerous pending applications worldwide. These patents cover a wide range of applications, from epilepsy treatment to GLP-1 drug delivery, reinforcing the company’s authority in drug delivery innovation.
Research and Development
Lexaria operates a licensed in-house research laboratory, conducting preclinical and clinical studies to validate its technology. Recent studies have shown promising results in enhancing the performance of GLP-1 drugs, cannabinoids, and antiviral formulations. The company is also exploring new applications in cardiovascular and neurological health.
Geographical Reach
Lexaria generates revenue primarily from the United States and Canada, with plans to expand its global footprint through strategic partnerships and licensing agreements.
Conclusion
Lexaria Bioscience Corp. is at the forefront of drug delivery innovation, leveraging its patented DehydraTECH™ technology to address critical challenges in the pharmaceutical industry. By enabling more effective oral formulations, the company is poised to disrupt markets dominated by injectable drugs, offering significant benefits to patients and healthcare providers alike.
Lexaria Bioscience Corp. (NASDAQ:LEXX, LEXXW) announced the granting of its 24th patent, titled "Compositions Infused with Nicotine Compounds and Methods of Use Thereof," enhancing its global intellectual property portfolio. This Australian patent allows the use of DehydraTECH technology for various nicotine forms, potentially increasing product value. Previous studies show DehydraTECH delivers nicotine significantly faster than conventional methods. Additionally, the company issued 36,700 stock options to staff at an exercise price of $3.39.
Lexaria Bioscience Corp. (NASDAQ:LEXX, LEXXW) reported significant findings from an animal study evaluating its DehydraTECH formulation of sildenafil, showing a 74% increase in drug delivery at 4 minutes compared to a generic control. The study indicated a 70% higher maximum concentration (Cmax) and a 37% improvement in total delivery (AUC). Results showed potential for developing faster-acting sildenafil formulations. However, improvements did not achieve statistical significance, necessitating further studies.
Lexaria Bioscience Corp. (NASDAQ:LEXX, LEXXW) shared an annual letter from CEO Chris Bunka, highlighting successes and strategic directions for the company. The focus remains on advancing the DehydraTECH drug delivery technology, aimed at overcoming industry inertia and regulatory challenges. Lexaria reported a growth in shareholder base, with average shares owned by NOBO shareholders increasing by 216% in 2021. The company's institutional ownership has also surged, ranging between 9% and 16%. The aim is to leverage this momentum for potential regulatory and commercial success in 2022.
Lexaria Bioscience Corp. (NASDAQ:LEXX) recently highlighted a study demonstrating cannabinoids' potential to inhibit SARS-CoV-2 infection.
Dr. Richard van Breeman noted that oral delivery of cannabinoids is recommended over smoking or vaping for effectiveness.
Lexaria's DehydraTECH™ technology enhances cannabinoid delivery, with applications in therapeutic formulations.
The study found cannabinoid acids can block cellular entry of the virus, presenting significant implications for treatment strategies.
Lexaria holds a strong patent portfolio, with ongoing research into pharmaceutical applications.
Lexaria Bioscience Corp. (NASDAQ:LEXX, LEXXW) has received early Independent Review Board approval for its DehydraTECH-CBD hypertension study, HYPER-H21-4, scheduled to begin dosing by April 2022. This study, funded through existing cash resources, aims to assess the treatment's efficacy in reducing blood pressure among 60 volunteers aged 45-70. The $28 billion hypertension market presents significant growth potential, especially in emerging economies. With a comprehensive analysis including blood pressure monitoring and brain imaging, Lexaria seeks to validate DehydraTECH-CBD as a promising anti-hypertensive therapy.
Lexaria Bioscience Corp. (NASDAQ:LEXX, LEXXW) announced a media and digital marketing agreement with SRAX to enhance investor engagement over the next year. This follows substantial progress made by the company in 2021, with plans for an extensive 2022 including a human hypertension study and a nicotine study. Lexaria will issue 224,299 restricted shares valued at $1.2 million to SRAX for its services. The agreement aims to maximize visibility through a sustained marketing campaign, leveraging SRAX's analytical capabilities.
Lexaria Bioscience Corp. (NASDAQ:LEXX, LEXXW) announces the near completion of its human clinical study HYPER-H21-3, which is exploring the effects of DehydraTECH-CBD on acute pulmonary hypertension. The study involved a placebo-controlled trial with 16 volunteers receiving a 300mg dose of DehydraTECH-CBD. Blood samples are currently being analyzed, with results expected soon. This research aims to contribute to the understanding of DehydraTECH-CBD as a treatment for hypertension and will be submitted to the FDA as part of their investigational drug research program.
Lexaria Bioscience Corp. (NASDAQ:LEXX)(NASDAQ:LEXXW) has released follow-up results from clinical study HYPER-H21-2, indicating that its DehydraTECH-CBD significantly reduces arterial stiffness after just one day of dosing. This finding suggests potential applications beyond hypertension, including in cardiovascular health. Notably, pulse wave velocity (PWV) was measured at 8.1 ± 0.3 m/s for DehydraTECH-CBD versus 8.3 ± 0.3 m/s for placebo, with all comparisons yielding statistically significant results (p < 0.01). Future studies, including the upcoming HYPER-H21-4, will explore these findings further.
Lexaria Bioscience Corp. (Nasdaq:LEXX)(Nasdaq:LEXXW) announces ambitious R&D plans for 2022, focusing on its DehydraTECH platform. Key studies include an investigation into heart disease and hypertension, as well as oral nicotine delivery alternatives. With funding of approximately USD$15 million secured, Lexaria aims to enhance drug delivery for treatments including dementia, rheumatoid disease, and diabetes. The company is debt-free and expects its cash reserves to sustain operations until at least Q2 2023. Strategic partnerships are planned post-data generation.
Lexaria Bioscience Corp. (NASDAQ:LEXX, LEXXW) has announced a new hypertension study, HYPER-H21-4, aimed at evaluating its DehydraTECH-CBD. This ambitious study involves 60 participants aged 45-70 and aims to gather data over six weeks, assessing various health metrics. Positive results could aid regulatory approval for DehydraTECH-CBD as a hypertension treatment. Additionally, updates on three ongoing studies show promising potential in blood pressure reduction. The global hypertension market represents a significant opportunity, valued at $28 billion annually.