Welcome to our dedicated page for Kala Pharmaceuticals news (Ticker: KALA), a resource for investors and traders seeking the latest updates and insights on Kala Pharmaceuticals stock.
Kala Pharmaceuticals Inc (NASDAQ: KALA) is a clinical-stage biopharmaceutical company pioneering novel therapies for severe ocular diseases through its proprietary MSC-S platform and nanoparticle drug formulations. This page provides authorized updates on KALA's clinical developments, regulatory milestones, and research advancements.
Investors and researchers will find verified press releases covering Phase 2/3 trial progress for lead candidate KPI-012 in PCED treatment, FDA designations for rare disease therapies, and peer-reviewed study publications. All content is curated to meet strict journalistic standards for accuracy in biopharmaceutical reporting.
The news archive includes updates on corneal healing therapies, retinal disorder research collaborations, intellectual property developments, and scientific conference presentations. Content is organized chronologically with clear sourcing to enable efficient tracking of the company's progress in ocular regenerative medicine.
Bookmark this page for direct access to Kala Pharmaceuticals' official announcements, including trial enrollment updates, partnership disclosures with academic institutions, and manufacturing scale-up progress. Check regularly for the latest validated information on this innovative developer of first-in-class ocular biologics.
Kala Pharmaceuticals (NASDAQ: KALA) has enrolled its first patient in the CHASE Phase 2b clinical trial for KPI-012, targeting top-line data by 1Q 2024. The company closed a $31.0 million private placement financing, extending its cash runway into 1Q 2025. Following the sale of its commercial portfolio to Alcon in July 2022, Kala reported a net loss of $12.8 million for Q4 2022, down from $47.6 million in Q4 2021. R&D expenses increased to $3.3 million, primarily due to costs related to KPI-012 development. As of December 31, 2022, Kala had cash and cash equivalents of $70.5 million.
Kala Pharmaceuticals (NASDAQ:KALA) announced the FDA's acceptance of its IND application for KPI-012, its lead product candidate targeting persistent corneal epithelial defect (PCED). The company is set to initiate a Phase 2b clinical trial in 1Q 2023 with topline data expected in 1Q 2024. Additionally, Kala completed a private placement financing, raising $25 million, bringing total proceeds to $31 million. KPI-012 aims to be the first approved treatment for PCED, a rare eye condition affecting approximately 100,000 individuals annually in the U.S.
Kala Pharmaceuticals announced the submission of an IND application for KPI-012 to the FDA, targeting Persistent Corneal Epithelial Defect (PCED). The company plans to initiate a Phase 2b trial by Q4 2022, with topline data projected for Q1 2024. Upon FDA acceptance, Kala will receive additional financing that extends its cash runway into Q1 2025. KPI-012 addresses a rare eye disease, impacting around 100,000 individuals annually in the U.S., and has the potential to become the first approved treatment for PCED. Mark Iwicki highlighted the significance of this advancement in ocular therapies.
Kala Pharmaceuticals, Inc. (NASDAQ:KALA) has entered into a definitive agreement for a private placement to raise up to $31 million. The first tranche includes the sale of 76,813 shares of common stock at $5.75 per share, and 9,666 shares of Series E Preferred at $575.00 per share, expected to close by December 1, 2022. The second tranche, contingent on FDA acceptance of their IND application for KPI-012 in treating persistent corneal epithelial defect, could yield an additional $25 million. Proceeds will advance the clinical development of KPI-012.
Kala Pharmaceuticals, Inc. (NASDAQ:KALA) plans to initiate a Phase 2/3 trial for KPI-012, targeting Persistent Corneal Epithelial Defect (PCED), with topline data expected in Q1 2024. The company ended Q3 2022 with $52.4 million in cash, sufficient to fund operations into Q2 2024. Net product revenues fell to $0.4 million from $3.1 million year-over-year, while R&D expenses increased to $5.4 million. The recent gain of $47 million from selling its commercial business to Alcon is noteworthy, as is the 1-for-50 reverse stock split. The company aims for significant advancements in rare ocular diseases.
Kala Pharmaceuticals (NASDAQ: KALA) has appointed Dr. Marjan Farid to its Board of Directors. Dr. Farid is a recognized expert in ophthalmology, specializing in corneal diseases and patient care at the Gavin Herbert Eye Institute, UCI. Her insights will be pivotal as Kala advances its lead product candidate, KPI-012, into Phase 2/3 studies for treating persistent corneal epithelial defect (PCED). KPI-012 has shown potential in addressing severe ocular diseases linked to impaired corneal healing. This leadership change aims to enhance the company's development capabilities and patient treatment options.
Kala Pharmaceuticals, Inc. (NASDAQ: KALA) announced a 1-for-50 reverse stock split effective October 20, 2022, with trading on a split-adjusted basis starting October 21, 2022. The split will reduce the outstanding shares from approximately 73.2 million to about 1.46 million. This decision was approved by stockholders at a special meeting held on October 19, 2022, and aims to enhance the stock's price and compliance with Nasdaq listing requirements. Stockholders' percentage interest will remain unaffected, except for any rounding of fractional shares.
Kala Pharmaceuticals, Inc. (NASDAQ:KALA) has announced its participation in the H.C. Wainwright 24th Annual Global Investment Conference, with a pre-recorded fireside chat available from September 12, 2022, at 7:00 a.m. ET. The conference will be held virtually and in New York, NY, and management will be available for one-on-one meetings. Kala focuses on developing therapies for rare eye diseases, including its lead product candidate KPI-012 for persistent corneal epithelial defects, which has received orphan drug designation from the FDA.
Kala Pharmaceuticals, Inc. (NASDAQ:KALA) announced the grant of non-statutory stock options to two new employees as an inducement award under NASDAQ Listing Rule 5635(c)(4). The company granted stock options to purchase a total of 35,000 shares, with an exercise price of $0.33 per share, the closing price on August 15, 2022. The options vest over four years, with the first 25% vesting on the one-year anniversary of employment. Kala is focused on innovative therapies for rare eye diseases, with its lead candidate, KPI-012, under clinical development for persistent corneal epithelial defect.
Kala Pharmaceuticals, Inc. (NASDAQ:KALA) announced a dividend of one one-thousandth of a share of Series D Preferred Stock for each outstanding share of common stock, record date August 29, 2022. The Series D shares will collectively vote on a reverse stock split alongside common stockholders. Holders of these shares will not have voting rights on other matters and will be redeemed if not present at the meeting or if approved for a reverse stock split. Detailed information will be available in an upcoming Form 8-K filing.
