Welcome to our dedicated page for Jazz Pharmaceuticals Plc news (Ticker: JAZZ), a resource for investors and traders seeking the latest updates and insights on Jazz Pharmaceuticals Plc stock.
Jazz Pharmaceuticals plc (Nasdaq: JAZZ) generates frequent news across neuroscience and oncology, reflecting its focus on serious diseases such as sleep disorders, rare epilepsies, HER2-driven cancers and aggressive brain tumors. This news page aggregates company press releases and third-party coverage so readers can follow how Jazz’s clinical programs, marketed medicines and corporate actions evolve over time.
Visitors can expect updates on clinical trial results and data presentations for products like Epidiolex/Epidyolex (cannabidiol), Xywav (low-sodium oxybate), Ziihera (zanidatamab-hrii) and Modeyso (dordaviprone). Jazz regularly announces new Phase 3 and Phase 4 findings, real-world evidence analyses, and translational research presented at major meetings such as the European Epilepsy Congress, American Epilepsy Society Annual Meeting, World Sleep Congress, ASCO Gastrointestinal Cancers Symposium and the Society for Neuro-Oncology Annual Meeting.
News items also cover regulatory milestones, such as indications granted by the U.S. Food and Drug Administration and other health authorities, as well as designations like Breakthrough Therapy, Fast Track and Orphan Drug status for certain oncology assets. Corporate announcements may include executive appointments, board changes, investor webcasts, participation in healthcare conferences and legal or settlement updates disclosed in tandem with SEC filings.
For investors, clinicians and patients researching JAZZ, this page offers a centralized view of how Jazz Pharmaceuticals communicates progress in sleep medicine, epilepsy, oncology and neuro-oncology. By reviewing the news feed over time, readers can see how key programs advance from early data readouts through larger trials, regulatory interactions and post-approval evidence generation.
Jazz Pharmaceuticals (Nasdaq: JAZZ) announced FDA acceptance with Priority Review of an sBLA for Ziihera (zanidatamab-hrii) combinations as first-line therapy for adult patients with HER2+ unresectable locally advanced or metastatic gastric, GEJ, or gastroesophageal adenocarcinoma (GEA).
The FDA set a PDUFA target action date of August 25, 2026. The submission uses the RTOR program and is supported by pivotal HERIZON-GEA-01 data showing added benefit when combining zanidatamab with chemotherapy ± tislelizumab. The FDA previously granted Breakthrough Therapy designation for these combinations.
Jazz Pharmaceuticals (Nasdaq: JAZZ) will report 2026 first quarter financial results on May 5, 2026 after U.S. market close. Management will host a webcast at 4:30 p.m. ET to discuss results and provide a business and financial update.
Interested parties may register in advance; a replay will be available via the Investors section of the company website.
Jazz Pharmaceuticals (Nasdaq: JAZZ) will present clinical and real-world data for Ziihera (zanidatamab-hrii) and Zepzelca (lurbinectedin) at ASCO 2026, May 29–June 2 in Chicago. Presentations include rapid oral PD-L1 subgroup analyses from HERIZON-GEA-01 and IMforte maintenance analyses, plus seven poster presentations across GI, lung and sarcoma sessions.
Highlights include PFS/OS across PD-L1 subgroups, GI tolerability analyses, ctDNA profiling, real-world treatment patterns, and IMforte molecular-subtype outcomes.
Jazz Pharmaceuticals (Nasdaq: JAZZ) will present six abstracts, including one oral presentation, at the 2026 American Academy of Neurology Annual Meeting (April 18-22, Chicago).
Data include a 6-month EpiCom analysis showing behavioral improvements with Epidiolex in TSC-associated seizures and DUET study findings on higher-dose Xywav benefits for narcolepsy.
Jazz Pharmaceuticals (Nasdaq: JAZZ) will participate in the 25th Annual Needham Healthcare Conference on April 15, 2026. Management will join a fireside chat at 8:45 a.m. PT / 11:45 a.m. ET / 4:45 p.m. IST.
An audio webcast will be available via the company’s Investors site, with a replay archived for 30 days.
American Nutrition Association and Jazz Pharmaceuticals (NYSE:JAZZ) announced a collaboration on March 24, 2026 to advance evidence-based sodium reduction education for people with narcolepsy and idiopathic hypersomnia. The initiative emphasizes sodium’s role in blood pressure and cardiovascular risk, cites average U.S. intake (~3,400 mg/day) versus recommended 1,500–2,300 mg, and notes CVD causes ~700,000 U.S. deaths annually. The program will produce patient and clinician resources to identify sodium exposures (food, beverages, medications) and encourage actionable sodium-reduction strategies for at-risk sleep-disorder populations.
Jazz Pharmaceuticals (Nasdaq: JAZZ) announced seven presentations at AACR 2026 (April 17-22) highlighting clinical and preclinical progress across its oncology programs.
Key items include Phase 2 NeoZanHER results showing a 30% pathologic complete response (pCR) rate with zanidatamab at six weeks, mechanistic multi-omics on zanidatamab, preclinical JZP898 tumor-localized interferon activity, and imipridone (dordaviprone) combination studies.
Jazz Pharmaceuticals (Nasdaq: JAZZ) reported record 2025 total revenue of $4.3 billion (up 5% YoY) and 4Q25 revenue of $1.2 billion (up 10% YoY). Key drivers included Xywav $1.7B (+12%), Epidiolex $1.1B (+9%), and Modeyso launch sales of $48M. GAAP net loss was $356M for 2025 with non-GAAP adjusted net income of $522M. Jazz expects 2026 total revenues of $4.25–$4.50 billion and plans an sBLA submission for zanidatamab under RTOR in 1Q26 with potential 1L HER2+ GEA launch in 2H26.
Jazz Pharmaceuticals (Nasdaq: JAZZ) will participate in two investor conferences in March 2026: TD Cowen 46th Annual Health Care Conference on March 3, 2026 and Barclays 28th Annual Global Healthcare Conference on March 12, 2026.
Fireside chat times: March 3 at 7:30 a.m. PT / 10:30 a.m. ET / 2:30 p.m. GMT, and March 12 at 7:00 a.m. PT / 10:00 a.m. ET / 2:00 p.m. GMT. An audio webcast and a replay archived for 30 days will be available via the company's Investors website.
Jazz Pharmaceuticals (Nasdaq: JAZZ) will report fourth quarter and full year 2025 financial results on February 24, 2026 after the close of U.S. markets. Management will host a live webcast at 4:30 p.m. ET / 9:30 p.m. GMT to discuss results and provide a business and financial update.
Interested parties may register in advance via the Investors section of the Jazz Pharmaceuticals website. A replay will be posted to the investor site for on‑demand access.