Welcome to our dedicated page for Ionis Pharmaceuticals news (Ticker: IONS), a resource for investors and traders seeking the latest updates and insights on Ionis Pharmaceuticals stock.
Ionis Pharmaceuticals, Inc. (NASDAQ: IONS) is a leading biotechnology company headquartered in Carlsbad, California. Founded in 1989, Ionis has been pioneering the discovery and development of antisense drugs, with an impressive portfolio of over 1300 patents. Ionis focuses on creating innovative RNA-targeted therapies for complex diseases, particularly in the areas of cardiovascular, metabolic, neurological, and rare genetic disorders.
Ionis has successfully brought several groundbreaking medicines to market. Notable achievements include the development of Spinraza, in collaboration with Biogen, which was launched in 2016 to treat spinal muscular atrophy, a rare neuromuscular disorder. In 2023, Biogen also launched Qalsody for ALS, further extending the impact of Ionis' antisense technology.
Through its cardiovascular-focused subsidiary, Akcea Therapeutics, Ionis has introduced drugs like Tegsedi for ATTR amyloidosis and Waylivra in Europe for cardiology indications. The company continues to advance its pipeline with promising candidates such as olezarsen, an investigational RNA-targeted therapy for familial chylomicronemia syndrome (FCS). Ionis' ongoing Phase 3 trials for olezarsen have shown promising results, with significant reductions in triglyceride levels and improvements in related health outcomes.
Ionis' commitment to innovation and patient care is also evident in its robust financial health and strategic partnerships. With a deep understanding of disease biology and cutting-edge technology, Ionis continues to drive advancements in RNA therapies and gene editing, aiming to deliver life-changing medicines for patients around the world.
Recently, Ionis announced positive clinical trial results for several of its investigational drugs and plans to pursue regulatory approvals for these therapies. The company's pipeline is well-positioned to address unmet medical needs in various therapeutic areas, promising a steady flow of new treatments in the coming years.
For more detailed information about Ionis Pharmaceuticals, its products, and career opportunities, visit their official website at www.ionispharma.com.
Ionis Pharmaceuticals (NASDAQ: IONS) announced the presentation of its advances in ATTR amyloidosis therapies at the 2021 Peripheral Nerve Society Annual Meeting, scheduled for June 12-13 and 25-27. The company highlights its commitment to innovating antisense therapies for this condition. Key presentations include a plenary lecture by Dr. Frank Bennett and a panel discussion moderated by Dr. Kemi Olugemo. Additionally, multiple on-demand posters will address various aspects of TTR amyloidosis treatment, showcasing Ionis' ongoing research and development efforts in the field.
Ionis Pharmaceuticals has announced significant leadership changes in its board of directors. Joseph Loscalzo, M.D., Ph.D., has been appointed chairman, succeeding Stanley Crooke, who has retired but will remain as a scientific advisor. Allene M. Diaz has also joined the board. Dr. Loscalzo's background includes extensive experience at Harvard Medical School and numerous accolades in cardiovascular science. Diaz brings a wealth of experience from her previous roles in GlaxoSmithKline and other firms. These changes aim to bolster Ionis's strategy towards delivering over 12 novel RNA-targeted therapies by 2026.
Ionis Pharmaceuticals (Nasdaq: IONS) will present a company overview at several upcoming virtual investor conferences. Key dates include:
- June 1, 2021: William Blair 41st Annual Growth Stock Conference
- June 9, 2021: Goldman Sachs 42nd Annual Global Healthcare Conference
- June 15, 2021: Nasdaq 44th Investor Conference
- June 22, 2021: BMO Biopharma Day: Spotlight on Rare Disease and Ophthalmology
Live webcasts will be available on Ionis' website, with replays archived for a limited time.
Ionis Pharmaceuticals (Nasdaq: IONS) announced participation in virtual fireside chats at two major investor conferences. The Bank of America Healthcare Conference is scheduled for May 12, 2021, and the RBC Capital Markets Global Healthcare Conference on May 19, 2021. The company will provide updates on presentation times and changes via its website. Live webcasts will be accessible in the Investors & Media section, with replays available within 48 hours. Ionis is recognized for its leadership in RNA-targeted therapy and has three marketed medicines.
Ionis Pharmaceuticals (Nasdaq: IONS) announced its 2021 virtual Annual Meeting of Stockholders will take place on June 2, 2021, at 5:00 p.m. ET. All stockholders of record as of April 5, 2021, are invited to participate via a live webcast. The meeting will include a corporate update presented by CEO Brett P. Monia at 5:30 p.m. ET. Participants must have a 16-digit control number to join the meeting. Links for participation and further details are available on their website.
Ionis Pharmaceuticals reported its first-quarter 2021 results with total revenues of $112 million amidst a net loss of $45 million (non-GAAP). The quarter saw significant advancements, including the initiation of pivotal studies for FUS-ALS and Alexander disease programs and positive outcomes for the IONIS-PKK-LRx program, indicating potential changes in standard care for hereditary angioedema. The company remains optimistic, anticipating 12 or more products on the market by 2026, currently bolstered by $2.1 billion in cash following recent financial maneuvers.
Ionis Pharmaceuticals (NASDAQ: IONS) will host a live webcast on May 5, 2021, at 11:30 a.m. Eastern Time to discuss its first quarter 2021 financial results and provide updates on its pipeline and business progress. The event will detail the company's advancements in RNA-targeted therapy and highlight its established neurological and cardiometabolic franchises. Interested parties can access the webcast through the company's investor relations website, where a replay will also be available.
Ionis Pharmaceuticals has initiated a pivotal clinical study of its investigational medicine, ION373, targeting Alexander disease, a rare and fatal neurological disorder. This multi-center, double-blind study will involve up to 58 patients over a 60-week period, assessing the safety and efficacy of ION373 in reducing toxic GFAP levels in the brain. Alexander disease, caused by a genetic mutation, affects roughly one in a million births. ION373 has received orphan drug and rare pediatric disease designations from the FDA, highlighting its potential significance in the therapeutic landscape.
Ionis Pharmaceuticals announced the pricing of $550.0 million in 0% Convertible Senior Notes due 2026, increasing from the initial $500.0 million offering. The private placement is set to close on April 12, 2021. The expected net proceeds are around $536.2 million, earmarked for repurchasing existing notes, funding convertible note hedge transactions, and other corporate purposes, including R&D. The conversion rate is 17.2902 shares per $1,000 of notes, with an initial conversion price of $57.84 per share, representing a 32.5% premium over the last sale price.
Ionis Pharmaceuticals intends to offer $500.0 million of Convertible Senior Notes due 2026 in a private placement to qualified institutional buyers. An option for an additional $75.0 million is also available. Proceeds will be used to repurchase certain existing notes, cover convertible note hedge transactions, and support general corporate purposes including R&D and infrastructure expansion. The notes and associated warrants are not registered under the Securities Act and may not be sold in the U.S. without registration or an exemption.
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