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IN8bio Announces Upcoming Presentation at 2024 European Hematology Association Congress

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IN8bio (Nasdaq: INAB), a clinical-stage biopharmaceutical company, announced it will present updated interim results from their Phase 1 trial of INB-100 at the upcoming European Hematology Association (EHA) 2024 Congress in Madrid, June 13-16. INB-100 is a gamma-delta T cell therapy aimed at increasing survival and reducing cancer recurrence in leukemia patients post-haploidentical stem cell transplantation, without severe graft-versus-host disease. The presentation will be held on June 14, 2024, at 10:00 a.m. CEST by Dr. Joseph P. McGuirk. Abstracts are accessible on the EHA website, and the poster will be available on IN8bio's site following the session.

Positive
  • IN8bio will present updated interim results at the European Hematology Association 2024 Congress, a major scientific event.
  • The Phase 1 trial for INB-100 shows promise in increasing survival and reducing cancer recurrence in leukemia patients.
  • The therapy does not cause severe graft-versus-host disease, a significant advantage in post-transplant treatments.
  • The presentation at EHA Congress enhances IN8bio's visibility in the scientific and medical community.
Negative
  • The results being shared are interim and not final, which may impact investor confidence.
  • The success of INB-100 is still contingent on further clinical trials and regulatory approvals.
  • Potential risks include the usual uncertainties related to clinical-stage biopharmaceutical companies, such as trial failures or delays.

NEW YORK, May 14, 2024 (GLOBE NEWSWIRE) -- IN8bio, Inc. (Nasdaq: INAB) a clinical-stage biopharmaceutical company developing innovative gamma-delta T cell therapies, announced today a presentation at the European Hematology Association 2024 Congress, to be held June 13-16 in Madrid, Spain.

“We’re excited to share the latest updated interim results from our Phase 1 trial evaluating our gamma-delta T cell therapy INB-100 after haploidentical stem cell transplantation for patients with leukemia at the upcoming EHA congress,” said Trishna Goswami, M.D., Chief Medical Officer, IN8bio. “The data to date suggest that our approach could potentially increase survival and reduce the risk of cancer recurrence in adult patients with newly diagnosed or relapsed ALL, CML, AML, or MDS without causing severe graft-versus-host disease. We look forward to sharing greater details and our latest progress with the hopes of expanding the current treatment options for cancer patients.”

Details of the poster presentation are as follows:

Title: INB-100: Pilot Study of Donor Derived, Ex-Vivo Expanded/Activated Gamma-delta T Cell Infusion Following Haploidentical Hematopoietic Stem-Cell Transplantation and Post-Transplant Cyclophosphamide

Presentation Date/Time: Friday, June 14, 2024, 10:00 a.m. CEST
Submission ID: EHA-2057
Poster Session: P1460
Abstract Topic: Gene therapy, cellular immunotherapy and vaccination – Clinical
Presenter: Dr. Joseph P. McGuirk, M.D., Schutte-Speas Professor of Hematology-Oncology, Division Director, Hematologic Malignancies and Cellular Therapeutics, Medical Director, Blood and Marrow Transplant, The University of Kansas Cancer Center

Abstracts are available at https://ehaweb.org/congress/eha2024-hybrid-congress/eha2024-hybrid-congress. A copy of the poster presentation will be available at https://in8bio.com after the poster session begins.

For more information about the study, visit www.clinicaltrials.gov (NCT03533816).

About IN8bio

IN8bio is a clinical-stage biopharmaceutical company developing gamma-delta T cell-based immunotherapies for cancer patients. Gamma-delta T cells are a specialized population of T cells that possess unique properties, including the ability to differentiate between healthy and diseased tissue. The company’s lead program INB-400 is in a Phase 2 trial in glioblastoma multiforme (GBM). Additional programs include Phase 1 trials in solid and hematologic tumors, including INB-200 for GBM and INB-100 for patients with hematologic malignancies undergoing transplantation. For more information about IN8bio, visit www.IN8bio.com.

Forward-Looking Statements
This press release may contain forward-looking statements made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. These statements may be identified by words such as “aims,” “anticipates,” “believes,” “could,” “estimates,” “expects,” “forecasts,” “goal,” “intends,” “may,” “plans,” “possible,” “potential,” “seeks,” “will” and variations of these words or similar expressions that are intended to identify forward-looking statements, although not all forward-looking statements contain these words. Forward-looking statements in this press release include, but are not limited to, statements regarding the ability of IN8bio’s gamma-delta T cell therapy INB-100 to increase survival and reduce the risk of cancer recurrence in adult patients with newly diagnosed or relapsed ALL, CML, AML, or MDS without causing severe graft-versus-host disease; and IN8bio’s ability to expand the current treatment options for cancer patients. IN8bio may not actually achieve the plans, intentions, or expectations disclosed in these forward-looking statements, and you should not place undue reliance on these forward-looking statements. Actual results or events could differ materially from the plans, intentions, and expectations disclosed in these forward-looking statements as a result of various factors, including: uncertainties inherent in the initiation and completion of preclinical studies and clinical trials and clinical development of IN8bio’s product candidates, including patient enrollment and follow-up and IN8bio’s ability to meet anticipated deadlines and milestones; the risk that IN8bio may not realize the intended benefits of its DeltEx platform; availability and timing of results from preclinical studies and clinical trials; whether the outcomes of preclinical studies will be predictive of clinical trial results; whether initial or interim results from a clinical trial will be predictive of the final results of the trial or the results of future trials; the risk that trials and studies may be delayed and may not have satisfactory outcomes; potential adverse effects arising from the testing or use of IN8bio’s product candidates; uncertainties related to regulatory approvals to conduct trials or to market products; IN8bio’s reliance on third parties, including licensors and clinical research organizations; and other important factors, any of which could cause our actual results to differ from those contained in the forward-looking statements, that are described in greater detail in the section entitled “Risk Factors” in our Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission (SEC) on May 9, 2024, as well as in other filings IN8bio may make with the SEC in the future. Any forward-looking statements contained in this press release speak only as of the date hereof, and IN8bio expressly disclaims any obligation to update any forward-looking statements contained herein, whether because of any new information, future events, changed circumstances, or otherwise, except as otherwise required by law.

Company Contact
IN8bio, Inc.
Glenn Schulman, PharmD, MPH
+1 203.494.7411
gdschulman@IN8bio.com

Investors
Meru Advisors
Lee M. Stern
lstern@meruadvisors.com

Media Contact
Kimberly Ha
KKH Advisors
917.291.5744
kimberly.ha@kkhadvisors.com


FAQ

What is IN8bio presenting at the EHA 2024 Congress?

IN8bio will present updated interim results from their Phase 1 trial of INB-100, a gamma-delta T cell therapy, aimed at increasing survival and reducing cancer recurrence in leukemia patients.

When is IN8bio's presentation at EHA 2024?

The presentation will take place on Friday, June 14, 2024, at 10:00 a.m. CEST.

Where is the EHA 2024 Congress being held?

The EHA 2024 Congress will be held in Madrid, Spain from June 13-16, 2024.

What is the focus of IN8bio's INB-100 therapy?

INB-100 is focused on increasing survival and reducing cancer recurrence in leukemia patients after haploidentical stem cell transplantation, without causing severe graft-versus-host disease.

How can I access the abstract for IN8bio's EHA 2024 presentation?

The abstract can be accessed on the EHA website, and a copy of the poster presentation will be available on IN8bio's website following the session.

IN8bio, Inc.

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