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Immunome Inc - IMNM STOCK NEWS

Welcome to our dedicated page for Immunome news (Ticker: IMNM), a resource for investors and traders seeking the latest updates and insights on Immunome stock.

Overview

Immunome Inc (IMNM) is a biopharmaceutical company pioneering the discovery and development of first-in-class antibody therapeutics. Utilizing its proprietary human memory B cell platform, Immunome harnesses the sophisticated immune responses of patients who have successfully combated disease, enabling a robust discovery process for novel antigens and native high-affinity antibodies. This innovative approach leverages advanced immunotherapy discovery techniques, strong oncology research, and precise high-content screening technologies.

Core Technology and Innovation

At the heart of Immunome's operation is its unique discovery engine, which effectively transforms the natural immune experience into targeted therapeutic solutions. By studying patients whose immune systems have already learned how to fight diseases like cancer, the company identifies potent antibodies with the potential to disrupt pathological processes. The proprietary platform allows for the simultaneous discovery of novel antigens and the associated, native antibodies, thereby fostering a diversified pipeline of therapeutic candidates that address critical unmet needs in oncology and infectious diseases.

Product Pipeline and Therapeutic Focus

Immunome's pipeline is structured around well-defined therapeutic areas. The primary focus is on oncology, where the scientific rationale is to deploy these native antibodies to target cancer-driving processes and provide substantial clinical benefits. In addition to cancer, the company explores infectious disease applications, including efforts to address conditions such as COVID-19. The broad pipeline strategy ensures that Immunome's research and development initiatives cover multiple fronts, offering potential breakthroughs through targeted antibody therapies.

Strategic Collaborations and Licensing

The company has successfully entered strategic collaborations that bolster its competitive edge. A notable example is the exclusive license agreement with Nectin Therapeutics, which granted Immunome rights to a panel of antibodies targeting a specific yet undisclosed antigen. Such agreements are testament to the technological strength and research capabilities of Immunome, reinforcing the company’s status as a center of innovation in antibody drug conjugate (ADC) development and immunotherapy research.

Research Methodology and Scientific Rigor

Immunome employs a battery of high-content screening technologies to isolate and validate high-affinity antibodies. This stringent screening process, combined with its deep understanding of human immunology, ensures that only therapeutic candidates with significant potential for clinical impact are advanced. The parallel discovery of novel antigens and their corresponding antibodies represents a sophisticated integration of immunological research and therapeutic development, setting a high standard in the biopharmaceutical industry.

Market Position and Competitive Landscape

Within the highly competitive field of biotechnology, Immunome differentiates itself by leveraging an innovative research process that is naturally aligned with patient-derived immune responses. This approach not only increases the scientific validity of its therapeutic candidates but also offers a unique perspective compared to traditional discovery platforms. Its emphasis on the human immune system provides a rich source of naturally optimized antibodies, positioning Immunome as a formidable competitor among companies focused on cancer immunotherapy and targeted treatments. The company’s collaboration ventures further amplify its capabilities and credibility in the realm of next-generation antibody therapeutics.

Operational Excellence and Business Model

Immunome's business model is centered on a sequential value inflection approach, where each stage of asset discovery and development leads to tangible milestones. This methodical model facilitates the efficient expansion of its therapeutic portfolio, establishing each asset with robust scientific data before progressing into further clinical development. The organization’s U.S.-centric operations are supported by a highly experienced leadership team known for their expertise in immunotherapy and ADC technology. This strategic handling of projects underscores a commitment to operational excellence and rigorous scientific methodology, ensuring that the company consistently meets high standards of research integrity and industry best practices.

Conclusion

In summary, Immunome Inc effectively combines advanced immunological research with state-of-the-art screening technologies to develop novel antibody therapeutics. Its focus on leveraging the natural immune responses of patients positions it uniquely in the competitive landscape of oncology and infectious disease treatments. Through strategic partnerships and an emphasis on scientific rigor, Immunome showcases a sustainable, expertise-driven approach to revolutionizing how we treat complex diseases. The comprehensive integration of discovery and clinical development processes highlights the company’s robust approach to creating highly selective and potentially transformative therapies.

Rhea-AI Summary

Immunome, Inc. (NASDAQ: IMNM) has submitted an Investigational New Drug (IND) application to the U.S. FDA for IMM-BCP-01, a novel three-antibody cocktail targeting SARS-CoV-2. This submission marks a significant milestone for Immunome as they prepare to conduct clinical studies. Preclinical testing shows that IMM-BCP-01 effectively reduces viral load and encompasses broad coverage against various COVID-19 variants. The project is funded by the U.S. Department of Defense, emphasizing its public health importance as COVID-19 continues to pose a threat.

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Immunome, Inc. (Nasdaq: IMNM) made progress in its antibody development, notably with IMM-BCP-01, targeting SARS-CoV-2 variants Lambda and Delta Plus. The company plans to submit an IND for IMM-BCP-01 this quarter, alongside anticipated topline data in H1 2022. Financially, for Q3 2021, R&D expenses reached $4.5M, while G&A expenses were $3.2M, leading to a net loss of $7.7M. As of September 30, 2021, cash reserves stood at $56.3M, indicating sufficient resources for ongoing projects.

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Immunome, Inc. (Nasdaq: IMNM), a biopharmaceutical company specializing in first-in-class antibody therapeutics, announced that its President and CEO, Purnanand Sarma, Ph.D., will present at the Stifel Healthcare Conference on November 15, 2021, at 8:00 a.m. ET. Interested listeners can access the live audio webcast via the Investor Relations section of Immunome's website, with a replay available for 30 days post-event. Immunome focuses on developing therapies for oncology and infectious diseases, including COVID-19, leveraging its proprietary human memory B cell platform.

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Immunome (Nasdaq: IMNM) has submitted a preprint manuscript detailing the preclinical efficacy of its SARS-CoV-2 antibody cocktail, IMM-BCP-01. This cocktail includes three monoclonal antibodies targeting regions of the spike protein, showing significant viral load reduction in infected hamsters. In tests, IMM-BCP-01 demonstrated a potent reduction of live viral titers by approximately 3.2 - 4 logs. This research indicates broad protective capabilities against multiple variants, supporting the potential for non-intravenous delivery in humans.

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Immunome, Inc. (Nasdaq: IMNM) presented findings on its anti-interleukin-38 monoclonal antibody program at the 2021 AACR-NCI-EORTC International Conference. The presentation revealed that the antibody effectively binds to IL-38, preventing its interaction with receptors and enhancing myeloid cell activity in vitro. In murine tumor models, the antibody significantly inhibited tumor growth. This data suggests that blocking IL-38 could potentially reverse immune suppression in tumors, providing a promising avenue for cancer treatment.

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Immunome, Inc. (NASDAQ: IMNM) announced an oral poster presentation of its anti IL-38 antibody program at the 2021 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, scheduled for October 7-10, 2021. The presentation, titled “IMM20324, a first-in-class, anti-interleukin-38 monoclonal antibody,” will cover the antibody's effectiveness in inducing robust anti-tumor responses in vivo. This marks a significant milestone for Immunome as it advances its therapeutic programs targeting oncology and infectious diseases, including COVID-19.

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Immunome, Inc. (Nasdaq: IMNM), a biopharmaceutical company focused on antibody therapeutics, announced that President and CEO Purnanand Sarma, Ph.D., will present at the Cantor Global Healthcare Conference on September 29, 2021, at 8:40 a.m. ET. Interested parties can access the live audio webcast through the company's Investor Relations page. Immunome leverages its human memory B cell platform to develop first-in-class therapeutics targeting oncology and infectious diseases, including COVID-19.

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Immunome, Inc. (Nasdaq: IMNM) announced that its President and CEO, Purnanand Sarma, will present at the Oppenheimer Fall Healthcare Life Sciences and MedTech Summit on September 21, 2021, at 9:55 a.m. ET. The live audio webcast can be accessed from the Investor Relations section of the company's website and will be available for replay for 30 days following the event. Immunome is focused on developing first-in-class antibody therapeutics, targeting oncology and infectious diseases, including COVID-19.

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Immunome, Inc. (Nasdaq: IMNM) announced that its antibody cocktail, IMM-BCP-01, showed strong neutralizing activity against the Lambda and Delta variants of SARS-CoV-2 in pre-clinical studies. The cocktail targets non-overlapping regions of the spike protein, proving effective against multiple strains. Funded by the U.S. Department of Defense, this promising therapeutic aims to combat COVID-19 variants. CEO Purnanand Sarma emphasized the ongoing support from pre-clinical data, reinforcing the importance of IMM-BCP-01 in fighting emerging variants.

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Immunome, Inc. (Nasdaq: IMNM) reported robust progress in Q2 2021, particularly in developing IMM-BCP-01, an antibody cocktail targeting SARS-CoV-2. The company secured increased funding from the Department of Defense and demonstrated strong neutralization activity against the Delta variant in preclinical tests. An IND filing for IMM-BCP-01 is planned for Q3 2021, with additional plans for an IL-38 immuno-oncology IND filing in Q4 2021. Financially, R&D expenses were $3.2 million, and the net loss totaled $5.2 million, with cash reserves at $59.8 million.

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FAQ

What is the current stock price of Immunome (IMNM)?

The current stock price of Immunome (IMNM) is $8.19 as of April 22, 2025.

What is the market cap of Immunome (IMNM)?

The market cap of Immunome (IMNM) is approximately 643.4M.

What is the core technology behind Immunome Inc?

Immunome uses a proprietary human memory B cell platform to harness the patient-derived immune response for the discovery of novel antigens and native antibodies.

In which therapeutic areas does Immunome primarily operate?

The company focuses on oncology and infectious diseases, including efforts to address conditions like COVID-19, using its advanced antibody discovery techniques.

How does Immunome discover therapeutic antibody candidates?

By leveraging the natural immune responses of patients and employing high-content screening methods, Immunome identifies high-affinity antibodies with significant therapeutic potential.

What differentiates Immunome's approach from traditional drug discovery methods?

Its unique platform utilizes the 'most highly educated' immune systems of patients, providing direct insights into successful immune responses, which helps in developing targeted and effective therapies.

What role do strategic partnerships play in Immunome's business model?

Collaborations, such as the exclusive licensing agreement with Nectin Therapeutics, enhance their pipeline by adding novel antibody candidates and reinforcing the scientific validity of their discovery platform.

What is the significance of Immunome's pipeline?

The pipeline, spanning preclinical and clinical assets, is designed to cover multiple therapeutic areas, ensuring that each development stage builds on strong scientific evidence and operational efficiency.

How does Immunome ensure the quality of its therapeutic candidates?

The company employs rigorous high-content screening technologies and a robust validation process to identify and select high-affinity antibodies with strong clinical potential.

How is Immunome positioned within the competitive biopharmaceutical landscape?

Immunome’s innovative use of patient-derived immune responses and its strategic collaborations place it as a distinct entity in the field, offering a unique approach to the development of antibody therapeutics.
Immunome Inc

Nasdaq:IMNM

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10.99%
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