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SeaStar Medical Holding Corp - ICU STOCK NEWS

Welcome to our dedicated page for SeaStar Medical Holding news (Ticker: ICU), a resource for investors and traders seeking the latest updates and insights on SeaStar Medical Holding stock.

SeaStar Medical Holding Corp (ICU) is a pioneering medical technology company dedicated to mitigating the life-threatening consequences of hyperinflammation on vital organs. Operating within the healthcare and therapeutic technology industry, the company develops innovative extracorporeal therapies designed to address systemic inflammation by targeting effector cells, which are central to immune response dysregulation. These effector cells can cause direct tissue damage and release pro-inflammatory cytokines that exacerbate immune imbalances, leading to severe complications such as organ failure.

Core Business and Technology

At the heart of SeaStar Medical's operations is its proprietary technology aimed at reducing hyperinflammation. The company's extracorporeal therapies are engineered to selectively target and modulate effector cells, thereby interrupting the cycle of inflammation that can lead to organ damage. This approach represents a significant advancement in the treatment of conditions where systemic inflammation plays a critical role, such as acute kidney injury, sepsis, and other severe inflammatory disorders. By focusing on the root cause of immune dysregulation rather than merely addressing symptoms, SeaStar Medical offers a novel solution with the potential to improve patient outcomes and reduce healthcare costs.

Business Model and Revenue Generation

SeaStar Medical's business model centers on the development and commercialization of its proprietary therapies. Revenue streams likely include direct sales of its medical devices to healthcare providers, licensing agreements with pharmaceutical or biotechnology companies, and potential partnerships for co-development or distribution. The company’s focus on extracorporeal therapies positions it as a key player in a specialized market segment, where demand for innovative solutions to manage systemic inflammation is growing.

Market Context and Competitive Landscape

SeaStar Medical operates within the broader medical technology and therapeutic solutions industry, a sector characterized by rapid innovation and stringent regulatory requirements. The company’s focus on hyperinflammation addresses a critical unmet need in healthcare, particularly in the management of acute and chronic conditions that involve immune system dysregulation. Competitors in this space may include other firms specializing in extracorporeal therapies, immunomodulation technologies, or inflammation-targeting pharmaceuticals. However, SeaStar Medical differentiates itself through its proprietary focus on effector cells, offering a targeted approach that sets it apart from more generalized treatments.

Challenges and Opportunities

Like many companies in the medical technology sector, SeaStar Medical faces challenges such as navigating complex regulatory pathways, securing clinical validation for its therapies, and competing against well-established players. However, the company’s unique approach to targeting effector cells provides a competitive edge, particularly if clinical outcomes demonstrate significant efficacy and safety advantages. Additionally, the growing recognition of hyperinflammation as a critical factor in various medical conditions presents a substantial market opportunity for the company’s solutions.

Significance in the Healthcare Industry

SeaStar Medical’s innovative therapies have the potential to transform the management of systemic inflammation, offering new hope for patients suffering from conditions with limited treatment options. By addressing the underlying mechanisms of immune dysregulation, the company contributes to a paradigm shift in how inflammatory diseases are treated, emphasizing precision and targeted intervention. This positions SeaStar Medical as a significant player in the advancement of medical technology and therapeutic solutions.

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SeaStar Medical Holding Corporation (Nasdaq: ICU) has announced a securities purchase agreement with an institutional investor to purchase over 10 million shares of common stock in a registered direct offering, along with the issuance of Series A and Series B warrants. The offering is expected to generate approximately $9.0 million in gross proceeds for the company.
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SeaStar Medical Holding Corporation (Nasdaq: ICU) appoints healthcare industry veteran David A. Green as Chief Financial Officer, effective January 10, 2024, as the company prepares for its first commercial launch for the Selected Cytopheretic Device Pediatric (SCD-PED).
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SeaStar Medical Holding Corporation (Nasdaq: ICU) has announced the issuance of U.S. Patent No. 11,866,730 for its Selective Cytopheretic Device (SCD) to treat subjects with inflammatory conditions. The SCD is a first-in-class, cell-directed extracorporeal therapy that selectively targets highly active inflammatory cells to quell the inflammatory response. This patent significantly fortifies the company's intellectual property portfolio and supports its strategy to validate the technology’s application across multiple high-value clinical indications. CEO Eric Schlorff highlighted the importance of controlling uncontrolled hyperinflammation, which can lead to vital organ damage and even death. The SCD therapy works to selectively target the most highly activated cells responsible for inflammation to potentially reverse the damage they cause. The newly issued patent covers methods for using SCD cartridges to treat inflammatory conditions by extracorporeally sequestering activated leukocytes and/or platelets and inhibiting or deactivating their inflammatory action, as well as methods for processing activated leukocytes and/or platelets. The patent’s claimed methods require the SCD cartridge to have specific ratios of surface area for sequestering activated leukocytes and/or platelets to SCD inner volume. Unlike pathogen removal and other blood-purification tools, the SCD selectively targets the most highly activated proinflammatory neutrophils and monocytes.
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SeaStar Medical Holding Corporation (Nasdaq: ICU) announces enrollment of 12 subjects in the NEUTRALIZE-AKI pivotal clinical trial for its patented, first-in-class, cell-directed Selective Cytopheretic Device (SCD) extracorporeal therapy. The company expects to receive FDA approval for its SCD Pediatric (SCD-PED) within the next 30 to 45 days and to commence commercialization in Q1 2024.
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SeaStar Medical Holding Corporation (Nasdaq: ICU) announces the formation of the SeaStar Medical Scientific Advisory Board (SAB), comprised of world-renowned international pediatric and adult clinical experts to advise on technology capabilities, share insights on emerging healthcare trends, and advise on critical care and acute kidney injury (AKI) clinical development programs.
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SeaStar Medical Holding Corporation (Nasdaq: ICU) Reports Financial Results and Business Update
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SeaStar Medical Holding Corporation announces FDA's Approvable Letter for their Selective Cytopheretic Device Pediatric (SCD-PED) for use in children with acute kidney injury and sepsis. The letter indicates that SeaStar's HDE application meets the requirements for an Approval Order, with minor modifications and revisions needed before commercialization. SeaStar expects to commence commercialization by the end of 2023 or Q1 2024.
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SeaStar Medical receives FDA Breakthrough Device Designation for its Selective Cytopheretic Device
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SeaStar Medical Holding Corporation to present at Dawson James Small Cap Growth Conference
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SeaStar Medical receives FDA correspondence indicating that their Selective Cytopheretic Device (SCD) Pediatric is expected to be approved within a month for use in children with acute kidney injury and sepsis. The device has shown a 77% reduction in mortality rate and no dialysis dependency at Day 60 in clinical studies. SeaStar Medical plans to commercialize the SCD for this indication by the end of 2023.
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FAQ

What is the current stock price of SeaStar Medical Holding (ICU)?

The current stock price of SeaStar Medical Holding (ICU) is $1.77 as of March 3, 2025.

What is the market cap of SeaStar Medical Holding (ICU)?

The market cap of SeaStar Medical Holding (ICU) is approximately 12.5M.

What does SeaStar Medical Holding Corp specialize in?

SeaStar Medical specializes in developing extracorporeal therapies to address hyperinflammation by targeting effector cells that drive immune dysregulation.

How does SeaStar Medical's technology work?

The company’s proprietary therapies target effector cells to reduce systemic inflammation, preventing tissue damage and organ failure caused by immune imbalances.

What market does SeaStar Medical operate in?

SeaStar Medical operates within the medical technology and therapeutic solutions industry, focusing on healthcare providers and patients affected by inflammatory conditions.

What challenges does SeaStar Medical face?

Key challenges include navigating regulatory approvals, demonstrating clinical efficacy, and competing with established medical technology companies.

What differentiates SeaStar Medical from competitors?

SeaStar Medical’s unique focus on targeting effector cells to modulate immune responses sets it apart from more generalized treatments for systemic inflammation.

Who are the likely customers of SeaStar Medical?

The company's primary customers are healthcare providers, including hospitals and clinics, that treat patients with conditions involving systemic inflammation.

What conditions can SeaStar Medical's therapies address?

SeaStar Medical’s therapies target conditions such as acute kidney injury, sepsis, and other disorders where systemic inflammation plays a critical role.

How does SeaStar Medical generate revenue?

Revenue streams likely include direct sales of medical devices, licensing agreements, and partnerships for co-development or distribution of its therapies.
SeaStar Medical Holding Corp

Nasdaq:ICU

ICU Rankings

ICU Stock Data

12.54M
6.98M
8.46%
4.94%
6.6%
Biotechnology
Surgical & Medical Instruments & Apparatus
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United States
DENVER