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G1 Therapeutics, Inc. - GTHX STOCK NEWS

Welcome to our dedicated page for G1 Therapeutics news (Ticker: GTHX), a resource for investors and traders seeking the latest updates and insights on G1 Therapeutics stock.

G1 Therapeutics, Inc. (Nasdaq: GTHX) is a commercial-stage oncology biopharmaceutical company committed to developing next-generation therapies to improve the lives of cancer patients. The company is based in Research Triangle Park, N.C., and leverages its proprietary kinase drug discovery platform to advance a pipeline of innovative compounds. G1's flagship product, COSELA® (trilaciclib), has been approved by the FDA to decrease the incidence of chemotherapy-induced myelosuppression in patients with extensive-stage small cell lung cancer (ES-SCLC).

In addition to COSELA, G1 Therapeutics is actively developing and evaluating trilaciclib in combination with other anti-cancer therapies. One notable project is the global, multi-center, randomized, placebo-controlled Phase 3 trial known as PRESERVE 2, which investigates trilaciclib in patients with metastatic triple-negative breast cancer (mTNBC). Preliminary results have shown promising survival benefits, indicating trilaciclib’s potential to protect bone marrow and enhance patient outcomes during cytotoxic therapy.

The company also engages in strategic partnerships to broaden its impact. For instance, G1 Therapeutics has entered agreements with companies like Pepper Bio and Jupiter Bioventures to advance the clinical development and commercialization of lerociclib, another promising CDK4/6 inhibitor. These collaborations aim to explore lerociclib's efficacy in treating various cancers, including HCC and radioprotection uses.

On the financial front, G1 Therapeutics reported revenues of $82.5 million for the full year 2023, reflecting significant growth from $51.3 million in the previous year. The company's ongoing commitment to innovation and strategic collaborations underscores its role as a key player in oncology therapeutics.

For more information, visit G1 Therapeutics and follow them on Twitter and LinkedIn.

Rhea-AI Summary
G1 Therapeutics, Inc. will host a webcast and conference call to provide a financial and corporate update for the second quarter 2023 on August 2, 2023, at 8:30 a.m. ET. Registration is required to access the call via telephone. A live and archived webcast will be available on the company's website for 90 days.
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G1 Therapeutics presents Phase 2 trial results of trilaciclib in patients with triple-negative breast cancer. Trilaciclib enhances T cell function and generation of memory T cells, potentially improving long-term immune surveillance. The drug also increases the ratio of CD8+ T cells to regulatory T cells, which is associated with overall survival and pathologic complete response. Trilaciclib's mechanism of action protects the immune system from damage caused by cytotoxic therapy. The results suggest potential longer-term benefits for patients.
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G1 Therapeutics appoints Monica Thomas as General Counsel and Chief Compliance Officer. The company also reports an inducement equity grant for Mrs. Thomas.
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G1 Therapeutics, Inc. presented preliminary results from its Phase 2 study of trilaciclib in patients with triple-negative breast cancer. Trilaciclib showed potential in reducing adverse events associated with sacituzumab govitecan-hziy, with a greater than 50% reduction in events such as neutropenia, anemia, and diarrhea. Patients with PD-L1(+) tumors had a higher response rate. Overall survival results are expected in Q1 2024.
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G1 Therapeutics, Inc. provided a corporate and financial update for Q1 2023. Net COSELA revenue grew by 18% compared to Q4 2022, and vial volume increased by 21%. The company strengthened its balance sheet through a monetization deal with Simcere, securing additional financing. The timing for the interim overall survival analysis of the pivotal Phase 3 trial in metastatic triple negative breast cancer (TNBC) has been updated to Q1 2024. G1 also completed enrollment in a Phase 2 trial of trilaciclib in combination with an antibody drug conjugate (ADC) in patients with metastatic TNBC.
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G1 Therapeutics, Inc. (GTHX) announced a webcast and conference call scheduled for May 3, 2023, at 8:30 a.m. ET, to provide a financial and corporate update for Q1 2023. The live event will discuss the company’s progress in developing COSELA® (trilaciclib), its first commercial product, and ongoing clinical trials across various solid tumors, including breast, lung, and bladder cancers. Participants are encouraged to register online to receive dial-in details, and a recorded version of the webcast will be available for 90 days post-event on the company's website. G1 Therapeutics continues to focus on advancing therapies that enhance patient outcomes in oncology.

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FAQ

What is the current stock price of G1 Therapeutics (GTHX)?

The current stock price of G1 Therapeutics (GTHX) is $7.15 as of September 18, 2024.

What is the market cap of G1 Therapeutics (GTHX)?

The market cap of G1 Therapeutics (GTHX) is approximately 377.2M.

What does G1 Therapeutics, Inc. specialize in?

G1 Therapeutics specializes in developing next-generation oncology therapeutics, focusing on small-molecule therapies to address unmet needs in cancer treatment.

What is COSELA® (trilaciclib)?

COSELA® (trilaciclib) is an FDA-approved drug designed to reduce chemotherapy-induced myelosuppression in patients with extensive-stage small cell lung cancer.

What is the PRESERVE 2 trial?

PRESERVE 2 is a global, multi-center, randomized, placebo-controlled Phase 3 trial investigating trilaciclib in patients with metastatic triple-negative breast cancer.

Where is G1 Therapeutics, Inc. located?

G1 Therapeutics is based in Research Triangle Park, North Carolina.

Who are G1 Therapeutics' key partners?

Key partners include Pepper Bio and Jupiter Bioventures, among others, focusing on developing and commercializing therapies like lerociclib.

What recent financial achievements has G1 Therapeutics reported?

For the full year 2023, G1 Therapeutics reported revenues of $82.5 million, a significant increase from $51.3 million in the previous year.

What is lerociclib?

Lerociclib is a differentiated oral CDK4/6 inhibitor being developed for various cancer treatments, including breast cancer and radioprotection.

How can I get more information about G1 Therapeutics?

To learn more, visit their website at www.g1therapeutics.com and follow them on Twitter and LinkedIn.

What types of cancer are G1 Therapeutics’ therapies targeting?

Their therapies target various cancers, including small cell lung cancer, triple-negative breast cancer, and potentially hepatocellular carcinoma.

What are G1 Therapeutics’ future goals?

G1 Therapeutics aims to provide innovative therapeutic advances for people living with cancer through ongoing research, clinical trials, and strategic partnerships.

G1 Therapeutics, Inc.

Nasdaq:GTHX

GTHX Rankings

GTHX Stock Data

377.22M
52.76M
10.92%
54.62%
6.46%
Biotechnology
Pharmaceutical Preparations
Link
United States of America
RESEARCH TRIANGLE PARK