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GlycoMimetics, Inc. (GLYC) is a clinical-stage biotechnology company dedicated to developing transformative therapies for serious diseases like sickle cell disease, cancer, and other conditions with high unmet medical needs. Founded in 2003, the company leverages its proprietary glycobiology technology to create novel glycomimetic drugs. These drugs are designed to mimic the structure of carbohydrates that play critical roles in various biological processes, potentially offering new avenues of treatment for complex diseases.
GlycoMimetics focuses on areas where carbohydrate biology is crucial, particularly in inflammation, cancer, and infection. The company's robust and diversified product pipeline includes multiple clinical candidates currently in various stages of development. These candidates aim to inhibit disease-related carbohydrate functions, thereby providing hope for patients who currently have limited treatment options.
The company's mission is to advance its research, clinical candidates, and ultimately deliver breakthrough treatments to improve patients' lives. GlycoMimetics is publicly traded on the NASDAQ under the symbol GLYC, reflecting its ongoing commitment to transparency and growth. Recent achievements and current projects highlight the company's commitment to innovation and patient care. GlycoMimetics continues to build strategic partnerships to enhance its research and development efforts, further solidifying its position as a leader in biotechnology.
By using expertise in carbohydrate chemistry and a deep understanding of carbohydrate biology, GlycoMimetics is at the forefront of developing treatments that address significant medical challenges. The company's ongoing projects and collaborations underscore its dedication to making a meaningful impact in the field of biotechnology.
GlycoMimetics (NASDAQ: GLYC) announced acceptance of two abstracts for poster presentations at the 63rd American Society of Hematology Annual Meeting, set for December 11-14, 2021. The presentations will detail preclinical studies of GMI-1359, a dual antagonist targeting CXCR4 and E-selectin. Data suggest GMI-1359 may enhance treatment efficacy for AML and potentially improve survival rates in patients, particularly those with FLT-3 ITD mutations. The drug has received both Orphan Drug and Rare Pediatric Designations for osteosarcoma.
GlycoMimetics, Inc. (Nasdaq: GLYC) announces that CEO Harout Semerjian will present at two upcoming healthcare conferences. The Stifel 2021 Virtual Healthcare Conference will take place on November 15, with GlycoMimetics presenting at 3:20 p.m. ET. The Jefferies London Healthcare Conference is scheduled for November 17, with the presentation at 11:20 AM GMT (6:20 AM ET). GlycoMimetics focuses on developing glycobiology-based therapies for cancers and inflammatory diseases, advancing its drug pipeline located in Rockville, MD.
GlycoMimetics (Nasdaq: GLYC) reported significant advancements in their investigational drug candidate, uproleselan. The Phase 3 trial for relapsed/refractory AML is nearing completion of enrollment, with top-line results expected post-2022. Recent data published in BLOOD showed a 69% MRD negativity rate among trial participants, enhancing uproleselan's profile. Financially, cash reserves stood at $101.9 million as of September 30, 2021, down from $137 million at year-end 2020, with R&D expenses increasing to $13.3 million due to ongoing clinical trials.
GlycoMimetics, Inc. (Nasdaq: GLYC) will hold a conference call on Tuesday, November 2, 2021, at 8:30 a.m. ET to discuss its third quarter financial results. Domestic participants can join at (844) 413-7154, while international callers can dial (216) 562-0466. A replay of the webcast will be available for 30 days on the company's website, and a phone replay will be accessible for 24 hours post-call. GlycoMimetics focuses on developing glycobiology-based therapies for cancers and inflammatory diseases, utilizing its unique chemistry platform.
GlycoMimetics announced promising results from a Phase 1/2 study of uproleselan, demonstrating a 69% MRD negative rate in relapsed/refractory AML patients. Published on September 16, 2021, in the journal BLOOD, the study indicates that uproleselan can enhance the efficacy of chemotherapy without increasing toxicity. The results support the ongoing Phase 3 trial, with hopes to establish uproleselan as the new standard of care for this patient population. Key findings include a median overall survival of 8.8 months for relapsed/refractory patients treated with the drug.
GlycoMimetics, Inc. (Nasdaq: GLYC) announced that CEO Harout Semerjian will present at the H.C. Wainwright & Co 23rd Annual Global Investment Virtual Conference from September 13-15, 2021. The presentation will be accessible on the company's website starting September 13 at 7:00 a.m. EDT for 30 days. GlycoMimetics, a clinical-stage biotechnology firm, focuses on developing glycobiology-based therapies for cancers and inflammatory diseases, with its lead drug candidate, uproleselan, currently in a Phase 3 trial for relapsed/refractory acute myeloid leukemia.
GlycoMimetics, Inc. (NASDAQ: GLYC) announced the grant of non-qualified stock options for 1,647,600 shares to Harout Semerjian, the new President and CEO, on August 3, 2021. The options were part of his inducement to accept the position, with a base exercise price of $2.03 per share. Vesting includes standard timelines and is contingent upon FDA approval of the candidate uproleselan for relapsed/refractory acute myeloid leukemia. GlycoMimetics is focused on developing therapies leveraging glycobiology for serious diseases.
GlycoMimetics, Inc. (Nasdaq: GLYC) reported a cash position of $118.9 million as of June 30, 2021. The company is advancing six clinical trials for its lead candidate, uproleselan, including three registration trials, with anticipated data flow beginning in 2022. Enrollment is expected to conclude by year-end 2021 in pivotal studies addressing AML. Additionally, the announcement of a new CEO, Harout Semerjian, aims to reinforce the company's strategic direction and pipeline development as it progresses towards commercialization.
GlycoMimetics, Inc. (Nasdaq: GLYC) appointed Harout Semerjian as CEO effective August 6, 2021, succeeding founding CEO Rachel King. Semerjian, with extensive oncology commercialization experience, will guide the firm through registrational trials for its lead candidate, uproleselan, in AML. King, who has led the company for 18 years, will remain as a board member and advisor. Semerjian’s experience includes leadership roles at Novartis and Ipsen, and he emphasizes the potential of uproleselan, which holds Breakthrough Therapy Designation from the FDA and Chinese regulators.
GlycoMimetics, Inc. (Nasdaq: GLYC) will hold a conference call on August 5, 2021, at 8:30 a.m. ET to discuss its second-quarter financial results. Domestic participants can dial (844) 413-7154, while international callers should use (216) 562-0466, entering participant code 9977599. A replay will be available on the company's website and via dial-in for 24 hours post-call. GlycoMimetics, based in Rockville, MD, focuses on glycobiology therapies targeting cancers like acute myeloid leukemia (AML) and has received Breakthrough Therapy Designation for its lead drug, uproleselan.
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