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Foghorn Therapeutics Inc. - FHTX STOCK NEWS

Welcome to our dedicated page for Foghorn Therapeutics news (Ticker: FHTX), a resource for investors and traders seeking the latest updates and insights on Foghorn Therapeutics stock.

Foghorn Therapeutics Inc., founded in 2015 and headquartered in Cambridge, Massachusetts, is a biopharmaceutical company focused on discovering and developing a new class of medicines. These medicines target genetically determined dependencies within the chromatin regulatory system using Foghorn's proprietary Gene Traffic Control® Platform. This platform provides an integrated, mechanistic understanding of how various components of the chromatin regulatory system interact, allowing the identification, validation, and potential drugging of targets within the system.

The company's lead programs include FHD-286 and FHD-609. FHD-286 is a small-molecule enzymatic inhibitor of BRG1 and BRM, targeting acute myeloid leukemia (AML) and uveal melanoma. FHD-609 is a protein degrader of BRD9 aimed at treating synovial sarcoma. Additionally, Foghorn is developing preclinical and discovery programs such as selective BRM targeting non-small-cell lung cancer and selective ARID1B modulators for bladder, ovarian, and endometrial cancer.

Foghorn has established a collaboration with Merck Sharp & Dohme Corp. to discover and develop novel oncology therapeutics against a transcription factor target. The company's financial stability is reflected in its cash and equivalents of approximately $259.9 million as of September 30, 2023, which supports its robust pipeline and strategic objectives for 2024 and beyond.

Recent Achievements and Current Projects:

  • Initiated a Phase 1 combination study of FHD-286 in AML with data expected in the second half of 2024.
  • Progress with the selective BRM inhibitor FHD-909, with an IND planned for the second quarter of 2024, primarily targeting non-small cell lung cancer.
  • Presented preclinical data showcasing selective CBP and EP300 degrader programs, demonstrating significant tumor growth inhibition without associated hematopoietic toxicity.
  • Announced multiple strategic milestones, including financial updates and corporate outlooks, reflecting continued progress across various therapeutic programs.

The company remains committed to advancing its preclinical and clinical programs, supported by collaborations and financial investments, with the goal of developing novel medicines that can transform the lives of patients with serious diseases.

Rhea-AI Summary
Foghorn Therapeutics Inc. provided an update on the progress of its clinical studies and preclinical programs, highlighting key milestones for its innovative precision medicine platform. The company's financials show a strong cash position, with significant collaboration revenues and controlled expenses.
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Foghorn Therapeutics Inc. announces the presentation of preclinical data for its pipeline programs at the 2024 AACR Annual Meeting, including FHD-909, a potential first-in-class BRM selective inhibitor. The data showcases significant progress in developing novel medicines targeting the chromatin regulatory system.
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Foghorn Therapeutics Inc. (Nasdaq: FHTX) to participate in Cowen’s 44th Annual Health Care Conference, showcasing its Gene Traffic Control® platform in oncology with potential to impact various diseases. The company's Chief Medical Officer will present on March 4, 2024, at 12:50 p.m. ET.
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Foghorn® Therapeutics Inc. (Nasdaq: FHTX) announced that Lilly has selected FHD-909, a first-in-class oral BRM selective inhibitor, for clinical development targeting BRG1 mutated non-small cell lung cancer. This collaboration is part of a strategic agreement with Lilly for the development of novel oncology medicines and includes a 50/50 co-development and co-commercialization agreement for Foghorn’s Selective BRM oncology program and an additional undisclosed oncology target.
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Foghorn Therapeutics Inc. (Nasdaq: FHTX) announces strategic objectives for 2024, including progress in AML combination study, preclinical data for FHD-286 and tyrosine kinase inhibitors, partnership with Loxo@Lilly, and IND filings. The company holds $259.9 million in cash, cash equivalents, and marketable securities.
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Foghorn Therapeutics Inc. (Nasdaq: FHTX) announced the departure of Chief Financial Officer, Allan Reine, to pursue another opportunity. The company is now searching for a successor. Dr. Reine's last day will be January 16, 2024.
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Foghorn® Therapeutics Inc. (Nasdaq: FHTX) to present clinical data from Phase 1 dose escalation study of FHD-286 in AML and MDS at ASH Annual Meeting
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Foghorn Therapeutics provides financial and corporate update, with a focus on the FHD-286 combination study in AML. The company presented preclinical data for its Selective EP300 and Selective CBP programs. It also announced a cash runway into the first half of 2026 and a collaboration with Loxo@Lilly. Collaboration revenue increased, while research and development expenses decreased.
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Foghorn Therapeutics will present new data from its preclinical and clinical programs at the 6th Annual Targeted Protein Degradation Summit and the Connective Tissue Oncology Society Annual Meeting. The presentations will cover advancements in degraders targeting key chromatin regulators involved in disease/oncology and preliminary results from a Phase 1 study of FHD-609 in patients with advanced synovial sarcoma or SMARCB1-loss tumors.
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Foghorn Therapeutics to present clinical data on FHD-286 at ESMO Congress 2023
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FAQ

What is the current stock price of Foghorn Therapeutics (FHTX)?

The current stock price of Foghorn Therapeutics (FHTX) is $5.14 as of December 20, 2024.

What is the market cap of Foghorn Therapeutics (FHTX)?

The market cap of Foghorn Therapeutics (FHTX) is approximately 280.2M.

What is Foghorn Therapeutics Inc. focused on?

Foghorn Therapeutics Inc. focuses on discovering and developing medicines targeting genetically determined dependencies within the chromatin regulatory system.

What are the main products under development by Foghorn Therapeutics?

The main products include FHD-286, a small-molecule enzymatic inhibitor for AML and uveal melanoma, and FHD-609, a protein degrader for synovial sarcoma.

What is the Gene Traffic Control® Platform?

The Gene Traffic Control® Platform is Foghorn's proprietary system that provides a mechanistic understanding of the chromatin regulatory system, enabling the identification and potential drugging of targets.

What are some of the recent achievements of Foghorn Therapeutics?

Recent achievements include initiating a Phase 1 study of FHD-286, progress with FHD-909, and presenting preclinical data for selective CBP and EP300 degrader programs.

What is Foghorn Therapeutics' financial condition?

As of September 30, 2023, Foghorn has cash and equivalents of approximately $259.9 million, supporting its various programs and strategic objectives.

Who are Foghorn Therapeutics' collaborators?

Foghorn has a collaboration with Merck Sharp & Dohme Corp. to discover and develop novel oncology therapeutics.

When was Foghorn Therapeutics founded?

Foghorn Therapeutics was founded in 2015.

Where is Foghorn Therapeutics headquartered?

Foghorn Therapeutics is headquartered in Cambridge, Massachusetts.

What are Foghorn Therapeutics' key areas of research?

Key research areas include acute myeloid leukemia, uveal melanoma, synovial sarcoma, non-small cell lung cancer, and various other solid tumors.

What is the strategic outlook for Foghorn Therapeutics in 2024?

Foghorn aims to achieve several important milestones, including data from their Phase 1 study of FHD-286 and progress with their BRM selective inhibitor and degrader programs.

Foghorn Therapeutics Inc.

Nasdaq:FHTX

FHTX Rankings

FHTX Stock Data

280.19M
44.98M
18.98%
72.11%
1.77%
Biotechnology
Pharmaceutical Preparations
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United States of America
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