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Exscientia Plc American Depositary Shares - EXAI STOCK NEWS

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Exscientia Plc (symbol: EXAI) is revolutionizing the field of small molecule drug discovery with its cutting-edge AI and machine learning technologies. As the first company to automate drug design, Exscientia surpasses traditional human efforts by leveraging vast repositories of discovery data combined with the expertise of seasoned drug hunters. At the core of the company's operations is a sophisticated AI-driven system that can design millions of novel, project-specific compounds. These compounds are pre-assessed for key criteria such as predicted potency, selectivity, and ADME (absorption, distribution, metabolism, and excretion).

The company's knowledge-driven systems enable rapid design-make-test cycles, generating new experimental data to refine their predictions continually. This iterative process ensures unparalleled progress toward project goals and has already resulted in significant productivity gains. Exscientia can generate drug candidates in roughly one-quarter of the time required by traditional methods.

Exscientia's technology platform uniquely combines human and computational capabilities to accelerate the design of novel, safe, and efficacious compounds for clinical testing in humans. The company focuses on the discovery and development of small-molecule drug candidates, aiming to bring innovative and effective treatments to market faster.

Recent achievements include successful partnerships and collaborations with leading pharmaceutical companies and research institutions. These collaborations enhance the company's ability to integrate new data, refine its predictive models, and expand its drug discovery capabilities. Financially, Exscientia remains robust, continually investing in research and development to maintain its leading position in AI-driven drug discovery.

For investors and stakeholders, Exscientia represents a pioneering force in the pharmaceutical industry, combining advanced technology with deep scientific expertise to transform drug discovery and development.

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Exscientia (Nasdaq: EXAI) released its Q1 2024 business update. The company reported positive early Phase 1 results for its BMS-partnered EXS4318 (PKC-theta inhibitor) program. Initial Phase I data for GTAEXS617 (CDK7 inhibitor) and EXS74539 (LSD1 inhibitor) are expected in 2H24. Exscientia's AI-driven automation lab aims to streamline drug design processes, targeting $40M in annual savings by 2025. The company plans to reduce headcount by 20-25% by year-end, expecting savings despite incurring $7.4M-$9.6M in severance costs. Financially, Q1 revenue was $6.7M, down from $7.3M YoY, while R&D expenses dropped to $29.8M from $42.2M. Exscientia projects its cash reserves will fund operations into 2027. The company will host a conference call on May 21 to discuss these updates.

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Exscientia (Nasdaq: EXAI) will announce its first quarter 2024 financial results on May 21, 2024, before U.S. market opening.

The company will host a conference call and webcast at 1:30 p.m. BST / 8:30 a.m. EDT to discuss business updates and review the financial outcomes.

Investors can access the webcast through the 'Investors and Media' section on Exscientia's website or dial in using provided phone numbers and conference ID.

A replay will be available for 90 days in the 'Events and Presentations' part of the site.

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Exscientia plc (Nasdaq: EXAI) announces advancements in pipeline, collaborations, and financial results for Q4 and full year 2023. Key highlights include progress in clinical trials, collaborations with pharma giants, and financial data showing revenue decline but strong cash position.
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Exscientia plc (Nasdaq: EXAI) will announce financial results for Q4 and full year 2023 on March 21, 2024. A conference call and webcast will be held to discuss business updates and financial performance.
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Exscientia plc (Nasdaq: EXAI) management to participate in investor conferences in March, including TD Cowen 44th Annual Health Care Conference, Barclays 26th Annual Global Healthcare Conference, and KeyBanc Capital Markets Life Sciences & MedTech Investor Forum. Webcasts of the presentations will be available on the company's website.
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Exscientia plc (Nasdaq: EXAI) has announced the initiation of the EXCYTE-2 study, an observational clinical study in acute myeloid leukaemia (AML) to investigate the relationship between ex vivo drug response (EVDR) measured in primary blood or bone marrow samples using the company’s deep learning, single-cell precision medicine platform and actual patient clinical response. The study aims to collect blood and bone marrow samples from first-line patients with AML, with an option to expand to second-line patients, representing areas of high unmet medical need with low survival rates. The study will also evaluate the activity of EXS74539 (‘539), Exscientia’s LSD1 inhibitor, in a large clinically annotated sample set, with the potential to support the ongoing development of ‘539, particularly in the selection of patients for future clinical trials. This study builds on other previously initiated precision medicine focused studies, including EXALT-1 and EXCYTE-1, and continues the company's focus on establishing AI-led ex vivo drug testing in human tissue samples as the most comprehensive strategy for preclinical testing of novel therapies, additive to mouse and other animal models.
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Exscientia plc (Nasdaq: EXAI) founder and Chief Executive, Professor Andrew Hopkins, has been appointed Commander of the Order of the British Empire (CBE) for services to Science and Innovation by His Majesty King Charles III. This recognition follows multiple prestigious honours recently received by both Andrew and Exscientia, the AI-driven precision medicine company he leads. Exscientia has won the Prix Galien USA for Best Digital Health Solution in late 2022 and the Prix Galien UK in the same category in May 2023. Andrew was also elected for life to two of the UK’s national academies, the Royal Society and the Academy of Medical Sciences. Additionally, Exscientia was named to the inaugural Fortune 50 AI Innovators list in November 2023.
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Exscientia plc (Nasdaq: EXAI) announces a new discovery stage programme with Sanofi, aiming to design a potential best-in-class molecule. Exscientia is eligible for up to $45 million in upfront and preclinical milestone payments, with additional development, regulatory, and sales-based milestone payments of over $300 million and tiered royalties on product sales.
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Exscientia plc (Nasdaq: EXAI) received a $2.3 million grant from Open Philanthropy to research harnessing the host interferon response for treating and preventing pandemic influenza. The grant is part of the wider Pandemic Antiviral Discovery initiative, aiming to develop novel antiviral medicines for future pandemics. Exscientia plans to utilize the grant to explore small molecule therapeutics that can activate the interferon response to control influenza and COVID-19 infections. This aligns with the company's commitment to pandemic preparedness, supported by the Bill & Melinda Gates Foundation in 2021.
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Exscientia plc (EXAI) management to participate in fireside chat at Evercore ISI HealthCONx Conference
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FAQ

What is the current stock price of Exscientia Plc American Depositary Shares (EXAI)?

The current stock price of Exscientia Plc American Depositary Shares (EXAI) is $5.005 as of November 4, 2024.

What is the market cap of Exscientia Plc American Depositary Shares (EXAI)?

The market cap of Exscientia Plc American Depositary Shares (EXAI) is approximately 647.6M.

What does Exscientia Plc specialize in?

Exscientia Plc specializes in the application of AI and machine learning to discover and design novel therapeutic small-molecule compounds.

How does Exscientia's AI-driven system improve drug discovery?

Exscientia's AI-driven system accelerates drug discovery by designing millions of novel compounds and pre-assessing them for key criteria, enabling rapid progress.

What are the benefits of Exscientia's AI-driven approach?

Exscientia's approach allows for faster discovery of drug candidates, reducing the time required to generate candidates to one-quarter of traditional methods.

Who are Exscientia's partners?

Exscientia collaborates with leading pharmaceutical companies and research institutions to enhance its drug discovery capabilities.

What are ADME criteria?

ADME stands for absorption, distribution, metabolism, and excretion, which are key criteria for assessing the potential success of drug compounds.

How does Exscientia combine human and computational capabilities?

The company integrates human expertise with AI systems to design and test novel compounds more effectively and efficiently.

What is the significance of Exscientia's rapid design-make-test cycles?

These cycles allow for continuous refinement and progress toward drug discovery goals, driving significant productivity gains.

What recent achievements has Exscientia made?

Exscientia has formed successful partnerships and collaborations, enhancing its ability to integrate new data and expand drug discovery capabilities.

What is the primary focus of Exscientia's research and development?

Exscientia focuses on discovering and developing small-molecule drug candidates using AI and machine learning technologies.

How does Exscientia ensure the safety and efficacy of its compounds?

Exscientia's AI-driven system pre-assesses compounds for predicted potency, selectivity, and other key criteria to ensure safety and efficacy before clinical testing.

Exscientia Plc American Depositary Shares

Nasdaq:EXAI

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647.57M
129.26M
25.9%
22.06%
2.23%
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