Welcome to our dedicated page for Evotec news (Ticker: EVO), a resource for investors and traders seeking the latest updates and insights on Evotec stock.
Evotec SE reports developments in drug discovery and development services, integrated R&D programs and strategic partnerships with pharmaceutical, biotechnology, academic and health-focused organizations. Its updates commonly cover small-molecule, biologics and cell-therapy work; AI/ML-enabled platforms such as Molecular Patient Databases, PanOmics and iPSC-based disease modeling; and therapeutic programs in oncology, cardiovascular and metabolic disease, neurology, immunology and infectious disease.
Recurring news also includes Just - Evotec Biologics manufacturing and biologics-development activity, grant-funded global-health work, preclinical candidate nominations, financial results and business updates. Governance items include Supervisory Board nominations, management appointments and operating-model changes tied to the company’s global R&D and partnership infrastructure.
Evotec SE has announced an extension and expansion of its collaboration with Related Sciences, focusing on advancing transformational new medicines through 2030. This partnership, initiated in early 2021, currently oversees over 15 drug discovery programs, leveraging Evotec's extensive expertise in integrated drug discovery and A.I./M.L. capabilities. The collaboration includes the discovery of covalent inhibitors, enhancing their multi-modality portfolio. Although the financial specifics of the agreement were not disclosed, Evotec is set to receive milestones, royalties, and an equity stake in RS assets developed under this partnership.
Evotec SE has appointed Laetitia Rouxel as its new Chief Financial Officer (CFO) effective April 1, 2023, replacing Enno Spillner. The Supervisory Board expressed gratitude for Spillner's contributions to the company's growth and success, including major financings and the NASDAQ listing. Rouxel brings over 25 years of experience in finance across various sectors, having held leadership roles at Pfizer, Danone, and Coty. She aims to leverage innovation to further drive Evotec's sustainable growth. The company focuses on drug discovery and development, boasting a portfolio of over 200 R&D projects targeting multiple therapeutic areas.
Evotec SE has entered a strategic collaboration with Janssen Biotech, Inc. to develop innovative immune-based therapies for oncology. This partnership, facilitated by Johnson & Johnson Innovation, allows Evotec to leverage its integrated discovery and development capabilities. The collaboration includes an undisclosed upfront payment, potential research and commercial milestones exceeding US$ 350 million, and tiered royalties on developed products. While Janssen will lead the clinical development, Evotec will focus on pre-clinical R&D and manufacturing.
Evotec SE has expanded its collaboration with Bristol Myers Squibb, adding two new drug discovery projects and designating a target-based program for development. This progress triggers total payments of US$ 26 million to Evotec. The collaboration, initiated in December 2016, aims to find disease-modifying treatments for neurodegenerative diseases, addressing a significant unmet medical need. Dr. Cord Dohrmann emphasized the ongoing success and productivity of this six-year partnership.
Exscientia (NASDAQ: EXAI) has announced a breakthrough in identifying patient responders to its A2A receptor antagonist, EXS-21546. Highlighting new data, the company revealed the adenosine burden score (ABS) that predicts the effectiveness of the drug in combating tumor immunosuppression. Exscientia is set to confirm ABS's validity in its upcoming IGNITE-AI Phase 1/2 trial, which combines '546 with a checkpoint inhibitor for patients with relapsed renal cell carcinoma and non-small cell lung cancer. This research will be presented at the ESMO Immuno-Oncology Congress from December 7-9 in Geneva.
Exscientia announced the approval of the IGNITE-AI clinical trial for EXS-21546, an A2A receptor antagonist, targeting relapsed/refractory renal cell carcinoma (RCC) and non-small cell lung cancer (NSCLC). The trial aims to enroll up to 110 patients to assess safety, efficacy, and pharmacokinetics. Notably, a unique biomarker signature will guide patient selection. The trial's first phase will establish the maximum tolerated dose, followed by an expansion phase to confirm efficacy. This is a significant step for Exscientia, enhancing its precision medicine approach.
Evotec SE, a leading life science company, reported a 19% revenue increase to €510.8 million for the first nine months of 2022, despite lower milestone payments compared to 2021. The base business grew by 27% to €502.7 million. Adjusted EBITDA decreased to €44.6 million due to high expansion costs and inflated energy prices. The company also announced multiple drug discovery agreements and launched its multi-omics data analysis platform PanHunter. The full-year revenue outlook remains unchanged, targeting between €715-735 million.
Evotec SE will announce its financial results for the first nine months of 2022 on November 9, 2022. A conference call will be held on the same day at 2:00 PM CET to discuss these results and provide a performance update. Participants can join via phone or through an audio webcast. Evotec operates globally with over 4,500 employees and focuses on discovering and developing therapeutics across various therapeutic areas, including neurology and oncology.
Evotec SE announced the completion of its acquisition of Central Glass Germany GmbH from Central Glass Co. Ltd. This strategic move enhances Evotec's drug substance manufacturing capacity, particularly focusing on rare diseases and precision therapeutics. The facility, located in Halle/Westphalia, Germany, is now operational and employs around 60 experts in chemical manufacturing. Evotec plans significant investments to establish this site as a leading center for rare disease drug substance manufacturing in Europe.
Evotec SE presented a transformative update on biologics manufacturing at its Capital Markets Day, focusing on global access to biotherapeutics. The company’s subsidiary, Just - Evotec Biologics, showcased its integrated AI/ML-based technologies, emphasizing a paradigm shift in the industry. Significant highlights include a $49.9 million contract with the U.S. Department of Defense for monoclonal antibody prototypes and the groundbreaking of a new manufacturing facility in Toulouse, France. CEO Dr. Werner Lanthaler underscored the need for modernized manufacturing to enhance accessibility to essential therapies.