Dyne Therapeutics Appoints Carlo Incerti, M.D., to its Board of Directors

Rhea-AI Summary

Dyne Therapeutics has appointed Carlo Incerti, M.D., to its Board of Directors, enhancing its leadership in developing therapeutic solutions for muscle diseases. Dr. Incerti brings over 30 years of experience in biopharmaceuticals, particularly in rare disease drug development, having previously worked at Sanofi Genzyme. His expertise aligns with Dyne’s focus on innovative therapeutics for genetically driven muscle diseases, utilizing the FORCE platform. This appointment is expected to strengthen Dyne's strategic direction as the company prepares for its initial clinical trials in the coming year.

Positive

• Appointment of Carlo Incerti, M.D., expected to enhance strategy and development in rare disease therapeutics.
• Dr. Incerti's extensive experience in global drug development could lead to improved execution in clinical trials.

Negative

• Concerns about continuity and experience gaps in management as new members join the board.

WALTHAM, Mass., March 03, 2022 (GLOBE NEWSWIRE) -- Dyne Therapeutics, Inc. (Nasdaq: DYN), a muscle disease company focused on advancing innovative life-transforming therapeutics for people living with genetically driven diseases, today announced the appointment of Carlo Incerti, M.D., to its Board of Directors. Dr. Incerti has more than three decades of experience in the biopharmaceutical industry, including in rare disease drug development.

“We are excited to have Carlo joining the Board as we advance Dyne’s programs into the clinic. He brings an extensive track record in global drug development, including from his time at Sanofi Genzyme where he played a leading role in pioneering therapies for rare and genetic diseases,” said Jason Rhodes, chairman of Dyne’s Board of Directors. “Carlo will be a great asset to Dyne, and we look forward to benefiting from his substantial expertise as we execute in the clinic.”

“I am enthusiastic about the potential of Dyne’s platform and pipeline to help address the urgent need for new therapeutic options for serious muscle diseases, given I have dedicated the majority of my career to the development of medicines for rare disorders,” said Dr. Incerti. “I look forward to partnering with other members of the Board and the leadership team as the company prepares to initiate its first clinical trials this year and furthers its mission of delivering life-transforming therapies for patients.”

Dr. Incerti is currently an operating partner at Forbion, a life sciences venture capital firm. Previously, he held several positions of increasing responsibility during his more than 25 years at Sanofi Genzyme, including senior vice president, chief medical officer and head of global medical affairs. He also served as senior vice president of global market access and held various roles at Genzyme’s European headquarters. He is chairman of the Board at Inversago Pharma, EryDel SpA, Azafaros B.V., VectorY Therapeutics, and a member of the Board of Numab Therapeutics AG. Dr. Incerti is also a founding member of the International Rare Diseases Research Consortium. He received his medical degree from the University of Modena and Reggio Emilia, Italy.

About Dyne Therapeutics
Dyne Therapeutics is building a leading muscle disease company dedicated to advancing innovative life-transforming therapeutics for people living with genetically driven diseases. With its proprietary FORCE™ platform, Dyne is developing modern oligonucleotide therapeutics that are designed to overcome limitations in delivery to muscle tissue seen with other approaches. Dyne has a broad portfolio of therapeutic programs for serious muscle diseases, including candidates for myotonic dystrophy type 1 (DM1), Duchenne muscular dystrophy (DMD) and facioscapulohumeral muscular dystrophy (FSHD). For more information, please visit https://www.dyne-tx.com/, and follow us on Twitter, LinkedIn and Facebook.

Forward-Looking Statements

This press release contains forward-looking statements that involve substantial risks and uncertainties. All statements, other than statements of historical facts, contained in this press release, including statements regarding Dyne’s strategy, future operations, prospects and plans, objectives of management, the potential of the FORCE platform, the expected timeline for submitting its response to the FDA’s clinical hold letter, submitting investigational new drug applications and dosing patients in trials and the anticipated design of the trials, constitute forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. The words “anticipate,” “believe,” “continue,” “could,” “estimate,” “expect,” “intend,” “may,” “might,” “objective,” “ongoing,” “plan,” “predict,” “project,” “potential,” “should,” or “would,” or the negative of these terms, or other comparable terminology are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Dyne may not actually achieve the plans, intentions or expectations disclosed in these forward-looking statements, and you should not place undue reliance on these forward-looking statements. Actual results or events could differ materially from the plans, intentions and expectations disclosed in these forward-looking statements as a result of various important factors, including: uncertainties inherent in the identification and development of product candidates, including the conduct of research activities and the initiation and completion of preclinical studies and clinical trials; uncertainties as to the availability and timing of results from preclinical studies; uncertainties as to the timing of and Dyne’s ability to submit and obtain regulatory clearance for investigational new drug applications and initiate clinical trials, including with respect to its response to the DYNE-251 clinical hold letter and its ability to obtain regulatory clearance of the DYNE-251 IND; whether results from preclinical studies will be predictive of the results of later preclinical studies and clinical trials; whether investigators and regulatory agencies will agree with the design of Dyne’s planned clinical trials; whether Dyne’s cash resources will be sufficient to fund the Company’s foreseeable and unforeseeable operating expenses and capital expenditure requirements; uncertainties associated with the impact of the COVID-19 pandemic on Dyne’s business and operations; as well as the risks and uncertainties identified in Dyne’s filings with the Securities and Exchange Commission (SEC), including the Company’s most recent Form 10-Q and in subsequent filings Dyne may make with the SEC. In addition, the forward-looking statements included in this press release represent Dyne’s views as of the date of this press release. Dyne anticipates that subsequent events and developments will cause its views to change. However, while Dyne may elect to update these forward-looking statements at some point in the future, it specifically disclaims any obligation to do so. These forward-looking statements should not be relied upon as representing Dyne’s views as of any date subsequent to the date of this press release.

Contact:

Dyne Therapeutics
Amy Reilly
areilly@dyne-tx.com
857-341-1203

FAQ

What is the significance of Carlo Incerti's appointment to Dyne Therapeutics?

Carlo Incerti's appointment is significant as he brings extensive experience in rare disease drug development, which can enhance Dyne's strategic execution.

How might Carlo Incerti's experience impact Dyne Therapeutics?

His experience is expected to provide valuable insights and improve the company's clinical trial processes for its therapeutic programs.

When is Dyne Therapeutics expected to initiate its first clinical trials?

Dyne Therapeutics plans to initiate its first clinical trials within the year following Carlo Incerti's appointment.