Cryoport Reports Third Quarter 2023 Financial Results
- 54% year-over-year growth in commercial Cell and Gene Therapy revenue for Q3 2023
- Affirmation of full year 2023 revenue guidance of $233 - $243 million
- Notable partnerships and acquisitions to accelerate long-term growth
- Leading market position as provider of technology-enabled, dependable, end-to-end supply chain solutions to the life sciences
- Solid performance from MVE Biological Solutions as clients' capex spending normalizes
- 7% year-over-year decrease in total revenue for Q3 2023 compared to Q3 2022
- 9% year-over-year decrease in Animal Health revenue for 9M 2023 compared to 9M 2022
- Net loss for Q3 2023 and 9M 2023 was higher compared to the same periods in 2022
- Adjusted EBITDA was negative for Q3 2023 and 9M 2023
- Third quarter 2023 commercial Cell and Gene Therapy revenue up
54% year-over-year - Supporting a record total of 670 clinical trials worldwide, with 81 in Phase 3
- Nine months 2023 revenue of
$176 million - Affirms full year 2023 revenue guidance of
-$233 $243 million
Jerrell Shelton, CEO of Cryoport, commented, "Our third quarter results were consistent with our expectations, reflecting current global economic and geopolitical challenges. However, we are seeing solid and sustained demand from our key life sciences and cell and gene therapy customers despite the current macroeconomic climate.
"We experienced a notable increase in commercial cell and gene therapy revenue, growing
"While demand for our cryogenic systems provided by MVE Biological Solutions was, as expected, lower than in previous years, it is important to point out that we maintained strong gross margins on our product revenue of
"During the third quarter, we continued to execute on our corporate strategy to accelerate our long-term growth through meaningful partnerships. This includes our collaboration with Cell and Gene Therapy Catapult, the premier cell and gene therapy manufacturing innovation center in
"Subsequent to quarter end, we completed the acquisition of Tec4med Lifescience, a solutions company with cutting-edge technology for comprehensive monitoring solutions, based in Darmstadt,
"These latest developments and our leading market position as provider of technology-enabled, dependable, end-to-end supply chain solutions to the life sciences add to our confidence that our long-term growth prospects are solid. We believe the combined power of our industry-leading brands, including Cryoport Systems, MVE Biological Solutions, CRYOPDP, and CRYOGENE, coupled with the capital projects we have underway, position Cryoport to capitalize on the continued growth of the life sciences and especially the cell and gene therapy industry, as more therapies make their way towards commercialization over these ensuing years," concluded Mr. Shelton.
In tabular form, revenue by market for Q3 2023 and 9M 2023, as compared to the same periods in 2022 was as follows:
Cryoport, Inc. and Subsidiaries | |||||||
Total revenues by market | |||||||
(unaudited) | |||||||
Three Months Ended | Nine Months Ended | ||||||
(in thousands) | 2023 | 2022 | % Change | 2023 | 2022 | % Change | |
Biopharma/Pharma | $ 46,979 | $ 48,570 | -3 % | 1 % | |||
Animal Health | 6,884 | 9,629 | -29 % | 23,620 | 25,985 | -9 % | |
Reproductive Medicine | 2,294 | 2,265 | 1 % | 7,741 | 7,625 | 2 % | |
Total revenues | $ 56,157 | $ 60,464 | -7 % | -1 % |
As of September 30, 2023, Cryoport supported 12 commercial therapies and a net total of 670 global clinical trials, a net increase of 27 clinical trials over September 30, 2022. The number of trials in Phase 3 was 81 as of the end of the third quarter of 2023. The number of trials by phase and region are as follows:
Cryoport Supported Clinical Trials by Phase | ||||
Clinical Trials | September 30, | |||
2021 | 2022 | 2023 | ||
Phase 1 | 240 | 268 | 275 | |
Phase 2 | 272 | 295 | 314 | |
Phase 3 | 70 | 80 | 81 | |
Total | 582 | 643 | 670 | |
Cryoport Supported Clinical Trials by Region | ||||
Clinical Trials | September 30, | |||
2021 | 2022 | 2023 | ||
459 | 496 | 516 | ||
EMEA | 92 | 105 | 112 | |
APAC | 31 | 42 | 42 | |
Total | 582 | 643 | 670 |
A total of six Cryoport supported Biologic License Applications (BLAs) or Marketing Authorization Applications (MAAs) were filed in the third quarter of 2023. During the remainder of 2023, we anticipate up to an additional five application filings, two new therapy approvals and an additional seven label/ geographic expansions or moves to earlier lines of treatment approved.
Financial Highlights
Total revenue for Q3 2023 was
- Biopharma/Pharma revenue was
, down$47.0 million 3% or for Q3 2023 compared to$1.6 million for Q3 2022. Revenue was mainly impacted by the anticipated weaker demand for cryogenic freezer systems and continued turnover of clinical trials, partially offset by the increase in revenue from the support of commercially launched therapies, demand for our bioservices solutions, and logistics services. Revenue from the support of commercial cell and gene therapies increased by$48.6 million , or$2.3 million 54% , to for Q3 2023.$6.6 million - Animal Health revenue was
for Q3 2023, compared to$6.9 million for Q3 2022, driven by decreased demand for cryogenic systems supporting bovine production.$9.6 million - Reproductive Medicine revenue was
for Q3 2023, consistent with Q3 2022, reflecting sustained demand for our CryoStork® logistics solutions.$2.3 million
Total revenue for 9M 2023 was
- Biopharma/Pharma revenue increased to
, a gain of$144.6 million 1% or for 9M 2023, compared to$1.3 million for the same period in 2022. Revenue from commercial therapies increased to$143.3 million , a gain of$15.9 million 31% or for 9M 2023.$3.8 million - Animal Health revenue was
, a decrease of$23.6 million 9% or for 9M 2023, compared to$2.4 million for the same period in 2022.$26.0 million - Reproductive Medicine revenue increased to
, a gain of$7.7 million 2% for 9M 2023, compared to for the same period in 2022.$7.6 million
Gross margin was
As a result of development initiatives, operating costs and expenses increased to
Net loss for Q3 2023 and 9M 2023 was
Net loss attributable to common stockholders was
Adjusted EBITDA was a negative
Cryoport held
Share Repurchase Update
On March 11, 2022, the Company announced that its board of directors authorized a repurchase program through December 31, 2025, authorizing the repurchase of common stock and/or convertible senior notes in the amount of up to
Note: All reconciliations of GAAP to adjusted (non-GAAP) figures above are detailed in the reconciliation tables included later in the press release. |
Outlook
Cryoport's management affirms the Company's full year 2023 revenue guidance range of
Additional Information
Further information on Cryoport's financial results is included in the attached condensed consolidated balance sheets and statements of operations, and additional explanations of Cryoport's financial performance are provided in the Company's Quarterly Report on Form 10-Q for the three months ended September 30, 2023, which is expected to be filed with the SEC on November 8, 2023. Additionally, the full report will be available in the SEC Filings section of the Investor Relations section of Cryoport's website at www.cryoport.com.
Earnings Conference Call Information
IMPORTANT INFORMATION: In addition to the earnings release, a document titled "Cryoport Third Quarter 2023 in Review", providing a review of Cryoport's financial and operational performance and a general business update, will be issued at 4:05 p.m. ET on Wednesday, November 8, 2023. The document is designed to be read in advance of the questions and answers conference call and will be accessible at http://ir.cryoport.com/events-and-presentations.
Cryoport management will host a conference call at 5:00 p.m. ET on November 8, 2023. The conference call will be in the format of a questions and answers session and will address any queries investors have regarding the Company's reported results. A slide deck will accompany the call.
Conference Call Information
Date: | Wednesday, November 8, 2023 |
Time: | 5:00 p.m. ET |
Dial-in numbers: | 1-888-886-7786 ( |
Confirmation code: | Request the "Cryoport Call" or Conference ID: 15559162 |
Live webcast: | 'Investor Relations' section at www.cryoport.com or click here.
Please allow 10 minutes prior to the call to visit this site to download and install any necessary audio software. |
The questions and answers call will be recorded and available approximately three hours after completion of the live event in the Investor Relations section of the Company's website at www.cryoport.com for a limited time. To access the replay of the questions and answers click here. A dial-in replay of the call will also be available to those interested, until November 15, 2023. To access the replay, dial 1-844-512-2921 (
About Cryoport, Inc.
Cryoport, Inc. (Nasdaq: CYRX), is a global provider of innovative products and services to the fast-growing Cell & Gene Therapy industry - enabling the future of medicine for a new era of life sciences. With 50 strategic locations covering the
For more information, visit www.cryoport.com or follow @cryoport on X, formerly known as Twitter at www.twitter.com/cryoport for live updates.
Forward-Looking Statements
Statements in this press release which are not purely historical, including statements regarding the Company's intentions, hopes, beliefs, expectations, representations, projections, plans or predictions of the future, are forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These forward-looking statements include, but are not limited to, those related to the Company's industry, business, long-term growth prospects, including expected growth in all of the Company's markets, plans, strategies, acquisitions, future financial results and financial condition, such as the Company's outlook and guidance for full year 2023 revenue and the related assumptions and factors expected to drive revenue, projected growth trends in the markets in which the Company operates, the Company's plans and expectations regarding the launch of new products and services, such as the expected timing and benefits of such products and services launches, the Company's expectations about future benefits of its acquisitions, the Company's expectations of solid performance from MVE Biological Solutions as the Company's clients' capex spending normalize, the Company's belief that it is positioned to capitalize on the continued growth of the life sciences and especially the cell and gene therapy industry, and anticipated regulatory filings or approvals with respect to the products of the Company's clients. It is important to note that the Company's actual results could differ materially from those in any such forward-looking statements. Factors that could cause actual results to differ materially include, but are not limited to, risks and uncertainties associated with the effect of changing economic and geopolitical conditions, supply chain constraints, inflationary pressures, the ongoing wars between
Cryoport, Inc. and Subsidiaries | |||||
Condensed Consolidated Statements of Operations | |||||
(unaudited) | |||||
Three Months Ended | Nine Months Ended | ||||
(in thousands, except share and per share data) | 2023 | 2022 | 2023 | 2022 | |
Revenues: | |||||
Service revenues | $ 36,022 | $ 33,296 | $ 107,062 | $ 100,791 | |
Product revenues | 20,135 | 27,168 | 68,933 | 76,128 | |
Total revenues | 56,157 | 60,464 | 175,995 | 176,919 | |
Cost of revenues: | |||||
Cost of service revenues | 20,803 | 18,913 | 59,887 | 56,742 | |
Cost of product revenues | 11,088 | 15,134 | 40,037 | 42,581 | |
Total cost of revenues | 31,891 | 34,047 | 99,924 | 99,323 | |
Gross Margin | 24,266 | 26,417 | 76,071 | 77,596 | |
Operating costs and expenses: | |||||
Selling, general and administrative | 36,023 | 30,235 | 108,066 | 87,420 | |
Engineering and development | 5,152 | 3,985 | 13,291 | 11,045 | |
Total operating costs and expenses: | 41,175 | 34,220 | 121,357 | 98,465 | |
Loss from operations | (16,909) | (7,803) | (45,286) | (20,869) | |
Other income (expense): | |||||
Investment income | 2,848 | 2,485 | 7,962 | 5,797 | |
Interest expense | (1,357) | (1,609) | (4,197) | (4,686) | |
Gain on extinguishment of debt, net | 5,679 | - | 5,679 | - | |
Other income (expense), net | (3,059) | 1,668 | 242 | (7,377) | |
Loss before provision for income taxes | (12,798) | (5,259) | (35,600) | (27,135) | |
Provision for income taxes | (471) | (57) | (1,598) | (762) | |
Net loss | $ (13,269) | $ (5,316) | $ (37,198) | $ (27,897) | |
Paid-in-kind dividend on Series C convertible preferred stock | (2,000) | (2,000) | (6,000) | (6,000) | |
Net loss attributable to common stockholders | $ (15,269) | $ (7,316) | $ (43,198) | $ (33,897) | |
Net loss per share attributable to common stockholders - basic and diluted | $ (0.31) | $ (0.15) | $ (0.89) | $ (0.69) | |
Weighted average common shares outstanding - basic and diluted | 48,904,102 | 48,520,696 | 48,660,646 | 49,148,558 |
Cryoport, Inc. and Subsidiaries | ||
Condensed Consolidated Balance Sheets | ||
September 30, | December 31, | |
2023 | 2022 | |
(in thousands) | (unaudited) | |
Current assets: | ||
Cash and cash equivalents | $ 59,473 | $ 36,595 |
Short-term investments | 406,389 | 486,728 |
Accounts receivable, net | 42,626 | 43,858 |
Inventories | 29,104 | 27,678 |
Prepaid expenses and other current assets | 11,548 | 9,317 |
Total current assets | 549,140 | 604,176 |
Property and equipment, net | 74,520 | 63,603 |
Operating lease right-of-use assets | 32,561 | 26,877 |
Intangible assets, net | 192,962 | 191,009 |
Goodwill | 148,954 | 151,117 |
Deposits | 1,656 | 1,017 |
Deferred tax assets | 863 | 947 |
Total assets | $ 1,000,656 | $ 1,038,746 |
Current liabilities: | ||
Accounts payable and other accrued expenses | $ 27,875 | $ 28,046 |
Accrued compensation and related expenses | 10,426 | 8,458 |
Deferred revenue | 1,580 | 439 |
Current portion of operating lease liabilities | 4,759 | 3,720 |
Current portion of finance lease liabilities | 195 | 128 |
Current portion of notes payable | 70 | 60 |
Total current liabilities | 44,905 | 40,851 |
Convertible senior notes , net | 377,955 | 406,708 |
Notes payable, net | 307 | 355 |
Operating lease liabilities, net | 29,757 | 24,721 |
Finance lease liabilities, net | 632 | 216 |
Deferred tax liability | 4,708 | 4,929 |
Other long-term liabilities | 484 | 451 |
Contingent consideration | 4,380 | 4,677 |
Total liabilities | 463,128 | 482,908 |
Total stockholders' equity | 537,528 | 555,838 |
Total liabilities and stockholders' equity | $ 1,000,656 | $ 1,038,746 |
Note Regarding Use of Non-GAAP Financial Measures
To supplement our financial statements, which are presented on the basis of
We believe that revenue growth is a key indicator of how Cryoport is progressing from period to period and we believe that the non-GAAP financial measures, revenue at constant currency and revenue growth rate at constant currency, are useful to investors in analyzing the underlying trends in revenue. Under GAAP, revenues received in local (non-
However, we also believe that data on constant currency period-over-period changes have limitations, particularly as the currency effects that are eliminated could constitute a significant element of our revenue and could significantly impact our performance. We therefore limit our use of constant currency period-over-period changes to a measure for the impact of currency fluctuations on the translation of local currency revenue into
Adjusted EBITDA is defined as net loss adjusted for interest expense, income taxes, depreciation and amortization expense, stock-based compensation expense, acquisition and integration costs, investment income, unrealized (gain)/loss on investments, foreign currency (gain)/loss, gain on insurance claim, gain on extinguishment of debt and charges or gains resulting from non-recurring events.
Management believes that adjusted EBITDA provides a useful measure of Cryoport's operating results, a meaningful comparison with historical results and with the results of other companies, and insight into Cryoport's ongoing operating performance. Further, management and the Company's board of directors utilize adjusted EBITDA to gain a better understanding of Cryoport's comparative operating performance from period to period and as a basis for planning and forecasting future periods. Adjusted EBITDA is also a significant performance measure used by Cryoport in connection with its incentive compensation programs. Management believes adjusted EBITDA, when read in conjunction with Cryoport's GAAP financials, is useful to investors because it provides a basis for meaningful period-to-period comparisons of Cryoport's ongoing operating results, including results of operations, against investor and analyst financial models, helps identify trends in Cryoport's underlying business and in performing related trend analyses, and it provides a better understanding of how management plans and measures Cryoport's underlying business.
Cryoport, Inc. and Subsidiaries | |||||
Reconciliation of GAAP net loss to adjusted EBITDA | |||||
(unaudited) | |||||
Three Months Ended | Nine Months Ended | ||||
(in thousands) | 2023 | 2022 | 2023 | 2022 | |
GAAP net loss | $ (13,269) | $ (5,316) | $ (37,198) | $ (27,897) | |
Non-GAAP adjustments to net loss: | |||||
Depreciation and amortization expense | 6,911 | 5,787 | 20,038 | 16,631 | |
Acquisition and integration costs | 675 | 721 | 6,304 | 1,544 | |
Investment income | (2,848) | (2,485) | (7,962) | (5,797) | |
Unrealized loss on investments | 2,336 | 3,914 | 2,300 | 12,550 | |
Gain on insurance claim | - | (4,815) | (2,642) | (4,815) | |
Foreign currency (gain)/loss | 710 | (128) | 114 | 628 | |
Interest expense, net | 1,357 | 1,609 | 4,197 | 4,686 | |
Stock-based compensation expense | 5,976 | 5,366 | 16,960 | 14,749 | |
Gain on extinguishment of debt, net | (5,679) | - | (5,679) | - | |
Other non-recurring costs | 250 | - | 250 | - | |
Income taxes | 471 | 57 | 1,598 | 762 | |
Adjusted EBITDA | $ (3,110) | $ 4,710 | $ (1,720) | $ 13,041 |
Cryoport, Inc. and Subsidiaries | |||||
Total revenues by market at constant currency for the three months ended September 30, 2023 | |||||
(unaudited) | |||||
Biopharma/ | Animal | Reproductive | Total | ||
(in thousands) | |||||
Non US-GAAP Constant Currency | $ 46,417 | $ 6,864 | $ 2,289 | $ 55,570 | |
As Reported | 46,979 | 6,884 | 2,294 | 56,157 | |
FX Impact [$] | 562 | 20 | 5 | 587 | |
FX Impact [%] | 1.2 % | 0.3 % | 0.2 % | 1.0 % | |
Cryoport, Inc. and Subsidiaries | |||||
Total revenues by market at constant currency for the nine months ended September 30, 2023 | |||||
(unaudited) | |||||
Biopharma/ | Animal | Reproductive | Total | ||
(in thousands) | |||||
Non US-GAAP Constant Currency | $ 145,411 | $ 23,993 | $ 7,742 | $ 177,146 | |
As Reported | 144,634 | 23,620 | 7,741 | 175,995 | |
FX Impact [$] | (777) | (373) | (1) | (1,151) | |
FX Impact [%] | (0.5 %) | (1.6 %) | (0.0 %) | (0.7 %) |
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SOURCE Cryoport, Inc.
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