Welcome to our dedicated page for Crispr Therapeut news (Ticker: CRSP), a resource for investors and traders seeking the latest updates and insights on Crispr Therapeut stock.
CRISPR Therapeutics AG (Nasdaq: CRSP) generates frequent news as a gene editing biopharmaceutical company advancing CRISPR/Cas9-based medicines and related platforms. News coverage commonly highlights progress with CASGEVY, described as the world’s first approved CRISPR-based therapy for eligible sickle cell disease and transfusion-dependent beta thalassemia patients, along with updates on the company’s expanding in vivo and cell therapy pipeline.
Investors and observers following CRSP news can expect regular announcements on clinical trial data, such as Phase 1 and Phase 2 results for programs like CTX310 targeting ANGPTL3 for cardiovascular and cardiometabolic disease, and zugo-cel (zugocaptagene geleucel) in autoimmune diseases and B-cell malignancies. Company press releases also report on regulatory milestones and commercialization developments for CASGEVY across multiple regions, including approvals, reimbursement agreements, and pediatric development plans.
CRISPR Therapeutics’ news flow also includes pipeline and platform updates for in vivo liver editing programs (CTX310, CTX320, CTX321, CTX340, CTX450), SyNTase-based CTX460 for alpha-1 antitrypsin deficiency, and regenerative medicine efforts in Type 1 diabetes. Collaboration announcements with partners such as Vertex Pharmaceuticals, Sirius Therapeutics, and Lilly, as well as participation in major scientific and investor conferences, are additional recurring themes.
On Stock Titan’s CRSP news page, readers can review these press releases and third-party articles in one place, track how clinical, regulatory, and partnership developments evolve over time, and use this information as context when assessing CRISPR Therapeutics’ stock and long-term gene editing strategy.
CRISPR Therapeutics (CRSP) announced promising results from its Phase 1 CARBON trial, evaluating CTX110 for treating large B-cell lymphoma (LBCL). The trial reported a 58% overall response rate (ORR) and a 38% complete response (CR) rate in patients treated at Dose Level 2 and above, with durable responses noted over 18 months. The safety profile was favorable, showing no Grade 3 or higher cytokine release syndrome. CRISPR plans to expand the CARBON trial into a potentially registrational study in Q1 2022, supporting the development of CTX110 as an effective 'off-the-shelf' therapy.
CRISPR Therapeutics announced a virtual event scheduled for October 12, 2021, at 4:30 p.m. ET to discuss clinical data from its ongoing Phase 1 CARBON trial. This trial evaluates the safety and efficacy of CTX110, an investigational CAR-T therapy targeting CD19 for treating relapsed or refractory B-cell malignancies. Investors and stakeholders can join via a conference call or through a live webcast. CTX110 is a gene-edited allogeneic CAR-T therapy developed by CRISPR Therapeutics, focusing on significant diseases using their proprietary CRISPR/Cas9 technology.
CRISPR Therapeutics (Nasdaq: CRSP) announced two poster presentations and an oral presentation at the upcoming Society for Immunotherapy of Cancer (SITC) Annual Meeting, scheduled for November 10-14, 2021, in Washington, D.C. The first poster focuses on CRISPR/Cas9 gene-edited CAR-T cells targeting CD33 in acute myeloid leukemia (AML), demonstrating promising preclinical efficacy without long-term toxicity. The joint oral presentation with Nkarta will cover strategies to enhance NK cell efficacy against solid tumors. These presentations highlight CRISPR's commitment to advancing gene-based therapies.
CRISPR Therapeutics announced participation in Chardan’s 5th Annual Genetic Medicines Conference on October 4, 2021, at 2:00 p.m. ET. Senior management will present insights on their innovative gene-based medicines targeting serious diseases. A live webcast will be accessible via the Company's website, with a replay available for 14 days post-event. The company is noted for its leading gene editing technology, CRISPR/Cas9, and has collaborations with Bayer and Vertex Pharmaceuticals.
CRISPR Therapeutics (Nasdaq: CRSP) will participate in the Canaccord Genuity 41st Annual Growth Conference on August 12, 2021, at 2:30 p.m. ET. The event aims to showcase the company's advancements in gene-based medicines for serious diseases using its CRISPR/Cas9 platform. A live webcast will be available on the company's website, with a replay accessible for 14 days post-event. CRISPR Therapeutics specializes in various therapeutic areas, including oncology and rare diseases, and collaborates with leading firms like Bayer and Vertex Pharmaceuticals.
CRISPR Therapeutics (Nasdaq: CRSP) reported strong financial results for Q2 2021, highlighting a net income of $759.2 million, a significant increase from a $79.7 million loss in Q2 2020. The revenue surge to $900.2 million was primarily due to a $900 million upfront payment from Vertex following their collaboration amendment. The company has dosed over 45 patients with CTX001 in ongoing trials for sickle cell disease and beta thalassemia, with enrollment completion expected in Q3 2021. Additionally, CTX130 received Orphan Drug Designation for T-cell lymphoma.
CRISPR Therapeutics (CRSP) has announced a strategic partnership with Capsida Biotherapeutics to develop gene editing therapies targeting familial amyotrophic lateral sclerosis (ALS) and Friedreich’s ataxia. CRISPR will lead the Friedreich’s ataxia program, while Capsida will focus on ALS. The collaboration combines CRISPR's gene-editing technology with Capsida's advanced AAV engineering capabilities, potentially enhancing therapeutic efficacy. Both companies can co-develop and share commercialization costs and profits from their respective programs.
Vertex Pharmaceuticals and CRISPR Therapeutics announced positive results from their investigational CRISPR/Cas9 gene-editing therapy, CTX001, in treating transfusion-dependent beta thalassemia (TDT) and severe sickle cell disease (SCD). Data from 22 patients indicated sustained treatment responses, with all TDT patients transfusion-free and SCD patients free from vaso-occlusive crises. The therapy aims to provide a one-time functional cure for these conditions. Ongoing trials are expected to finalize regulatory discussions soon.
CRISPR Therapeutics (Nasdaq: CRSP) has announced participation in three virtual investor conferences in June 2021. The events include the Jefferies Virtual Healthcare Conference on June 1 at 1:00 p.m. ET, the William Blair 41st Annual Growth Stock Conference on June 3 at 12:20 p.m. ET, and the Goldman Sachs 42nd Annual Global Healthcare Conference on June 8 at 3:00 p.m. ET. Live webcasts of these presentations will be accessible on the company's website, and recordings will be available for 14 days post-event.
Vertex Pharmaceuticals and CRISPR Therapeutics announced the acceptance of two abstracts for presentation at the EHA 2021 Virtual Congress. The studies focus on CTX001, a gene-editing therapy for Sickle Cell Disease (SCD) and Transfusion-Dependent Beta-Thalassemia (TDT). Both abstracts detail safety and efficacy results from ongoing clinical trials, with data on patients showing promising follow-up outcomes. CTX001 aims to alleviate severe symptoms by increasing fetal hemoglobin levels, potentially reducing transfusion needs and sickle crises.