Welcome to our dedicated page for Cellectar Biosciences news (Ticker: CLRB), a resource for investors and traders seeking the latest updates and insights on Cellectar Biosciences stock.
Cellectar Biosciences, Inc. (NASDAQ: CLRB) is a late-stage clinical radiopharmaceutical company developing targeted cancer drugs based on its proprietary Phospholipid Drug Conjugate (PDC) platform. The CLRB news feed on Stock Titan aggregates company announcements, scientific presentations and regulatory updates that reflect the progress of this oncology pipeline.
Investors and researchers following Cellectar’s news can track developments around its lead asset, iopofosine I 131, including data from the CLOVER WaM Phase 2b study in Waldenstrom’s macroglobulinemia, the CLOVER‑2 pediatric high‑grade glioma program, and investigator‑initiated work in head and neck cancer. News items also cover FDA designations such as Breakthrough Therapy, Orphan Drug, Rare Pediatric Disease and Fast Track, as well as EMA PRIME and orphan designations and feedback from the EMA’s Scientific Advice Working Party on a potential Conditional Marketing Authorization filing in Europe.
The CLRB news stream highlights updates on Auger‑ and alpha‑emitting candidates CLR 121125 (CLR 125) and CLR 121225 (CLR 225), including preclinical data in triple‑negative breast cancer and pancreatic ductal adenocarcinoma, clinical trial planning, and supply agreements for key radioisotopes like actinium‑225 and astatine‑211. Financial results, capital raises, warrant transactions, and reverse stock split actions reported in SEC‑linked press releases provide additional context on how the company funds its development plans.
By monitoring this page, users can review historical and ongoing disclosures about Cellectar’s clinical results, regulatory interactions, partnerships and financing activities, all drawn from company-issued news and related filings.
Cellectar Biosciences, Inc. (NASDAQ: CLRB) reported its financial results for Q3 2022, highlighting a net loss of $7.8 million, or $1.28 per share, compared to a loss of $5.8 million in Q3 2021. The company raised $10.7 million through direct and private placements, with plans to utilize funds for clinical studies and general corporate expenses. Notable developments include a 50% overall response rate in a Phase 2 study for multiple myeloma and a $2 million grant from the NCI to expand pediatric trials. Cash and equivalents totaled $17.8 million as of September 30, 2022, down from $35.7 million at year-end 2021.
Cellectar Biosciences, Inc. (NASDAQ: CLRB) announced the completion of a registered direct offering and private placements, raising approximately $10.7 million. The company sold 3,275,153 shares at $2.085 each and issued warrants for the same amount, along with pre-funded warrants for 1,875,945 shares. Proceeds will be allocated for clinical studies, research and development, working capital, and corporate purposes. The transaction was facilitated by Oppenheimer & Co. Inc. and complies with SEC regulations.
Cellectar Biosciences (NASDAQ: CLRB) announced a registered direct offering and concurrent private placements totaling approximately $10.7 million. The agreements involve the sale of 3,275,153 shares at $2.085 each and warrants for the same number of shares, along with pre-funded warrants for an additional 1,875,945 shares. The funds will be used for clinical studies, R&D, working capital, and corporate purposes. The transactions are expected to close on October 25, 2022. Oppenheimer & Co. Inc. acted as the sole placement agent.
Cellectar Biosciences (NASDAQ: CLRB) announced a $1.98 million grant from the National Cancer Institute to expand its Phase 1 study of iopofosine I-131 in pediatric patients with inoperable high-grade gliomas. The funding supports the transition to Part 1b of the study, focusing on optimal dosing after initial efficacy signals from Part 1a. HGGs are aggressive brain tumors with poor prognoses. Iopofosine delivers radioisotopes directly to cancer cells, showing promising early results, including extended progression-free survival for patients.
Cellectar Biosciences (NASDAQ: CLRB) announced promising findings from the Phase 2 CLOVER-1 study of iopofosine I-131 in patients with quad-class refractory multiple myeloma who failed anti-BCMA therapies. The study revealed an overall response rate (ORR) of 50% among seven patients with a median of nine prior therapies. The mean overall survival was reported at 9.1 months. Safety assessments indicated manageable side effects with no treatment discontinuations. The company aims to leverage these results to expand iopofosine's application in treating aggressive hematologic cancers.
Cellectar Biosciences, Inc. (NASDAQ: CLRB) reported its financial results for Q2 2022, highlighting a significant milestone in the Phase 2B trial of iopofosine for Waldenstrom's macroglobulinemia. The independent data monitoring committee recommended continuation of the trial. As of June 30, 2022, the company had $24.8 million in cash, down from $35.7 million at the end of 2021. R&D expenses were $4.5 million for Q2 2022, consistent with the previous year, while G&A expenses rose to $2.9 million, reflecting higher costs. The net loss for the quarter was $7.4 million, compared to $6.0 million in Q2 2021.
Cellectar Biosciences (Nasdaq: CLRB) announced a reverse stock split effective July 22, 2022, consolidating every ten shares into one new share. Post-split, approximately 6.1 million shares will be outstanding while the ticker symbol and par value remain unchanged. Stockholder rights will stay the same except for fractional shares, which will be cashed out. The company aims to enhance its share value and improve trading liquidity amid its ongoing development of targeted cancer therapies, particularly iopofosine, currently in pivotal clinical studies.
Cellectar Biosciences, Inc. (NASDAQ: CLRB) reported financial results for Q1 2022, emphasizing the continuation of its pivotal Phase 2b trial of iopofosine for Waldenstrom’s macroglobulinemia (WM) after a positive assessment from an independent data monitoring committee. The company had cash and equivalents of $30.6 million as of March 31, 2022. Net loss for the quarter was $6.1 million, down from $6.4 million in Q1 2021. R&D expenses decreased to approximately $3.9 million, while G&A expenses rose to $2.3 million, reflecting increased professional fees.
Cellectar Biosciences (NASDAQ: CLRB) announced that an independent Data Monitoring Committee has completed a futility/efficacy assessment of its pivotal Phase 2b study of iopofosine in Waldenstrom’s macroglobulinemia (WM) and recommended continuation. The study aims to enroll 50 patients, focusing on a primary endpoint of a 20% major response rate. Cellectar noted an encouraging 83.3% major response rate in a prior study. The pivotal trial will assess treatment-free survival and duration of response, further advancing Cellectar's mission in targeted cancer therapies.
Cellectar Biosciences has announced the appointments of Matthew Hagan as Vice President, Marketing and Strategic Alliances, and David Lasecki as Executive Director, Strategic Alliances. Both bring extensive experience in oncology therapeutics, which the company believes will aid its transition to a commercial-stage entity. Cellectar's pivotal trial for iopofosine, targeting Waldenstrom’s macroglobulinemia, is ongoing, with interim data expected soon. The company continues to develop its Phospholipid Drug Conjugate platform, aiming to enhance cancer treatment efficacy while reducing side effects.