Welcome to our dedicated page for ContraFect Corporation news (Ticker: CFRX), a resource for investors and traders seeking the latest updates and insights on ContraFect Corporation stock.
ContraFect Corporation (CFRX) maintains this comprehensive news hub for stakeholders tracking advancements in antimicrobial therapies. Our curated collection delivers essential updates on the biotechnology leader’s progress against drug-resistant infections through its pioneering lysin and monoclonal antibody platforms.
Access timely reports on clinical trial developments, regulatory milestones, and strategic collaborations shaping the future of hospital infection treatment. The resource serves investors and healthcare professionals alike with verified information about therapeutic candidates in development and their potential market impact.
Key updates include progress reports on antibacterial agents targeting multidrug-resistant organisms, financial disclosures demonstrating R&D commitment, and partnership announcements with research institutions. All content undergoes rigorous verification to ensure compliance with financial reporting standards.
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ContraFect Corporation (Nasdaq: CFRX) announced the dosing of the first patient in its Phase 1b/2 clinical study of exebacase for chronic prosthetic joint infections (PJI) due to Staphylococcus aureus or Coagulase-Negative Staphylococci. This randomized, double-blind, placebo-controlled study aims to evaluate the safety, pharmacokinetics, and efficacy of exebacase administered intra-articularly during a DAIR procedure. The study will be conducted in two parts over up to two years, with an early efficacy assessment at six weeks. ContraFect’s CEO emphasized the potential of exebacase to replace current surgical treatments and improve patients' quality of life by eradicating infections that have seen little improvement in clinical outcomes.
ContraFect Corporation (Nasdaq: CFRX), a clinical-stage biotech company, has reported significant data on CF-370, demonstrating its efficacy against an extensively drug-resistant (XDR) strain of Pseudomonas aeruginosa in a neutropenic rabbit pneumonia model. These findings were presented at the 33rd European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in April 2023. CF-370 exhibited notable antibacterial activity, significantly reducing bacterial density, especially when combined with amikacin. The mechanism of CF-370 involves rapid cell wall destabilization, providing hope for patients with life-threatening infections. The company's focus on addressing antibiotic resistance is underscored by the alarming mortality rates associated with such infections, which can reach 60% in patients suffering from HAP/VAP.