Welcome to our dedicated page for ContraFect Corporation news (Ticker: CFRX), a resource for investors and traders seeking the latest updates and insights on ContraFect Corporation stock.
ContraFect Corporation (CFRX) is a pioneering biotechnology company dedicated to combating life-threatening infectious diseases, particularly those prevalent in hospital settings. Given the alarming rise of drug-resistant and newly-emerging pathogens, hospital-acquired infections have become the fourth leading cause of death in the United States, following heart disease, cancer, and stroke.
ContraFect's core business revolves around the development and commercialization of protein and antibody therapeutic products. The company leverages its innovative lysin and monoclonal antibody platforms to target conserved regions of bacteria and viruses. Lysins are enzymes produced during the life cycle of bacteriophages, which are viruses that infect and kill bacteria. This unique approach positions ContraFect at the forefront of antimicrobial therapy, especially against multi-drug resistant pathogens.
Recent achievements have solidified ContraFect's leadership in this critical field. The company has made significant strides in advancing its therapeutic candidates through various stages of clinical development. These efforts are underscored by strategic partnerships and collaborations aimed at accelerating the discovery, acquisition, and development of novel protein and antibody products.
Financially, ContraFect remains committed to transparency and growth. The latest quarterly results reflect the company's robust financial health and strategic investments in research and development. These investments are crucial for maintaining its competitive edge and ensuring the successful commercialization of its therapeutic products.
ContraFect's dedication to addressing life-threatening infectious diseases is evident in its ongoing projects and future plans. The company continues to explore new avenues for therapeutic discovery, aiming to deliver first-in-class treatments that can effectively manage and eradicate drug-resistant infections.
For more detailed updates, follow ContraFect on Twitter @ContraFectCorp and LinkedIn, or contact their investor relations team.
ContraFect Corporation (Nasdaq: CFRX) announced the dosing of the first patient in its Phase 1b/2 clinical study of exebacase for chronic prosthetic joint infections (PJI) due to Staphylococcus aureus or Coagulase-Negative Staphylococci. This randomized, double-blind, placebo-controlled study aims to evaluate the safety, pharmacokinetics, and efficacy of exebacase administered intra-articularly during a DAIR procedure. The study will be conducted in two parts over up to two years, with an early efficacy assessment at six weeks. ContraFect’s CEO emphasized the potential of exebacase to replace current surgical treatments and improve patients' quality of life by eradicating infections that have seen little improvement in clinical outcomes.
ContraFect Corporation (Nasdaq: CFRX), a clinical-stage biotech company, has reported significant data on CF-370, demonstrating its efficacy against an extensively drug-resistant (XDR) strain of Pseudomonas aeruginosa in a neutropenic rabbit pneumonia model. These findings were presented at the 33rd European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in April 2023. CF-370 exhibited notable antibacterial activity, significantly reducing bacterial density, especially when combined with amikacin. The mechanism of CF-370 involves rapid cell wall destabilization, providing hope for patients with life-threatening infections. The company's focus on addressing antibiotic resistance is underscored by the alarming mortality rates associated with such infections, which can reach 60% in patients suffering from HAP/VAP.
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