CareDx to Host Symposium at CEoT Featuring the Latest Multimodality Innovations in Kidney and Lung Transplant Surveillance

Rhea-AI Summary

CareDx Hosts Innovative Symposium on Transplant Health

SOUTH SAN FRANCISCO, Calif., April 6, 2022 – CareDx, Inc. (Nasdaq: CDNA) announces its symposium, “Improved Precision with a Multimodality Approach,” at the American Society of Transplantation’s CEoT meeting, April 6-8. The event on April 7 will discuss multimodality surveillance advancements using AlloSure® dd-cfDNA and AlloMap® gene-expression profiling for kidney and lung transplants. NYU Langone Health's abstract on dd-cfDNA stability post-SARS-CoV-2 vaccination reinforces vaccine safety in kidney transplant recipients.

Symposium, “Improved Precision with a Multimodality Approach,” Reviews Innovative Solutions for a More Holistic View of Allograft Health

SOUTH SAN FRANCISCO, Calif., April 06, 2022 (GLOBE NEWSWIRE) -- CareDx, Inc. (Nasdaq: CDNA) – The Transplant Company™ focused on the discovery, development, and commercialization of clinically differentiated, high-value healthcare solutions for transplant patients and caregivers – today announced it will host the symposium, “Improved Precision with a Multimodality Approach,” during the annual American Society of Transplantation Cutting Edge of Transplantation (CEoT) virtual meeting taking place April 6-8.

The CareDx sponsored lunch symposium will take place on Thursday, April 7. The latest advancements in multimodality surveillance using CareDx’s AlloSure® donor-derived cell-free DNA (dd-cfDNA), AlloMap® gene-expression profiling, and other new emerging modalities for assessing allograft injury, rejection, and infection in kidney and lung transplantation will be presented.

Additionally, in an accepted abstract, “Kinetics of dd-cfDNA in Kidney Transplant Recipients Following SARS-CoV-2 Vaccination Booster Administration,” NYU Langone Health highlights the use of AlloSure Kidney for monitoring vaccine-related immunological graft injury. The study showed that the stability of dd-cfDNA after SARS-CoV-2 vaccine booster administration reinforces the vaccine’s safety profile in kidney transplant patients.

“CareDx is deeply committed to delivering innovative transplant solutions, and we are excited to share how our best-in-class technologies support and stratify early signs of rejection, help in clinical decision-making, and impact outcomes,” said Reg Seeto, CEO and President of CareDx. “This real-world data clearly demonstrates the power of our non-invasive multimodality solutions in helping to build the molecular patient profile integrated with predictive algorithms that will support timely interventions.”

Topics and speakers include:

• The Predictive Power of AlloSure Kidney: Findings from the ADMIRAL Study,¹ presented by Amishi Desai, DO, Associate Professor, Medical Director of Kidney and Pancreas Transplantation and Division Chief of Transplant Nephrology, Loyola University.
• Introduction to Multimodality Kidney Surveillance, presented by Abdolreza Haririan, MD, MPH, Medical Director of Kidney and Pancreas Transplantation, University of Maryland Medical Center; Professor of Medicine, University of Maryland School of Medicine.
• KidneyCare: Improved Precision with Multi-Modality, presented by Neeraj Singh, MD, FASN, FASH, Medical Director of Kidney and Pancreas Transplantation at the John C. McDonald Regional Transplant Center and Associate Professor of Medicine at LSU Health Sciences Center, Shreveport.
• The Entire Picture: LungCare and ALAMO Study² Findings, presented by Deborah Jo Levine, MD, Professor of Medicine in Pulmonary and Critical Care Medicine, University of Texas.

About CareDx – The Transplant Company
CareDx, Inc., headquartered in South San Francisco, California, is a leading precision medicine solutions company focused on the discovery, development and commercialization of clinically differentiated, high-value healthcare solutions for transplant patients and caregivers. CareDx offers testing services, products, and digital healthcare solutions along the pre- and post-transplant patient journey and is the leading provider of genomics-based information for transplant patients. For more information, please visit: www.CareDx.com.

Forward Looking Statements
This press release includes forward-looking statements related to CareDx, Inc., including statements regarding the potential benefits and results that may be achieved with CareDx’s hosting of a symposium featuring the latest multimodality innovations in kidney and lung transplant surveillance at CEoT (the “Symposium”). These forward-looking statements are based upon information that is currently available to CareDx and its current expectations, speak only as of the date hereof, and are subject to risks and uncertainties that could cause actual results to differ materially from those projected, including risks that CareDx does not realize the expected benefits of the Symposium; risks that the schedule, topics or panelists of the Symposium may be subject to changes; general economic and market factors; and other risks discussed in CareDx’s filings with the SEC, including the Annual Report on Form 10-K for the fiscal year ended December 31, 2021 filed by CareDx with the SEC on February 24, 2022, and other reports that CareDx has filed with the SEC. Any of these may cause CareDx’s actual results, performance or achievements to differ materially and adversely from those anticipated or implied by CareDx’s forward-looking statements. CareDx expressly disclaims any obligation, except as required by law, or undertaking to update or revise any such forward-looking statements.

CONTACTS:
CareDx, Inc.
Sasha King
Chief Marketing Officer
415-287-2393
sking@caredx.com

Investor Relations
Ian Cooney
(415) 722-4563
investor@CareDx.com

References:

1. Bu L, Gupta G, Pai A, et al, Clinical outcomes from the assessing donor-derived cell freeDNA monitoring insights of kidney allografts with longitudinal surveillance (ADMIRAL) study, Kidney International. (2022) 101, 793–803;doi: https://doi.org/10.1016/j.kint.2021.11.034
2. Keller M, Sun J, Mutebi C, et al. Donor-derived cell-free DNA as a composite marker of acute lung allograft Dysfunction in clinical care. The Journal of Heart and Lung Transplantation. December 26, 2021. doi: https://www.jhltonline.org/article/S1053-2498(21)02630-9/fulltext

FAQ

What is the purpose of the CareDx symposium on April 7, 2022?

The CareDx symposium, “Improved Precision with a Multimodality Approach,” aims to present advancements in multimodality surveillance for assessing allograft health in kidney and lung transplants.

What key topics will be discussed at the CareDx symposium?

Topics will include multimodality kidney surveillance, the predictive power of AlloSure Kidney, and findings from the ALAMO study related to lung transplants.

What is AlloSure and how is it used in transplantation?

AlloSure is a test that measures donor-derived cell-free DNA (dd-cfDNA) to assess allograft injury and rejection in transplant patients.

What significance does the NYU Langone Health study have for kidney transplant patients?

The study shows that stabilizing dd-cfDNA levels after SARS-CoV-2 vaccination indicates a positive safety profile for vaccines in kidney transplant recipients.

Who are the featured speakers at the CareDx symposium?

Featured speakers include Amishi Desai, Abdolreza Haririan, Neeraj Singh, and Deborah Jo Levine, covering various aspects of kidney and lung transplantation.